Patents by Inventor Ross Zirkle

Ross Zirkle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11046968
    Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: June 29, 2021
    Assignees: Dow AgroSciences LLC, DSM IP Assets B.V.
    Inventors: Terence A. Walsh, Daniel J. Gachotte, Cory M. Larsen, Scott Bevan, P. Ann Owens-Merlo, James G. Metz, Ross Zirkle
  • Patent number: 10925850
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: February 23, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Publication number: 20200390126
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: July 22, 2020
    Publication date: December 17, 2020
    Inventors: Kirk E. APT, Joseph W. PFEIFER, III, Jon Milton HANSEN, Paul Warren BEHRENS, Ross ZIRKLE, Tracey Lynn STAHL
  • Patent number: 10829794
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: November 10, 2020
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • Patent number: 10798952
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: October 13, 2020
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Patent number: 10757959
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: September 1, 2020
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Publication number: 20200199598
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Application
    Filed: December 2, 2019
    Publication date: June 25, 2020
    Inventors: Kirk E. APT, Leslie RICHTER, David SIMPSON, Ross ZIRKLE
  • Patent number: 10538772
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: January 21, 2020
    Inventors: Kirk E. Apt, Leslie Richter, David Simpson, Ross Zirkle
  • Patent number: 10392578
    Abstract: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: August 27, 2019
    Assignee: DSM IP Assets B.V.
    Inventors: Stephen Robert Cherinko, Robert Cody Kertis, Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle, Nasrin Tabayeh Burke, Krishna Raman, Neil Francis Leininger
  • Patent number: 10385289
    Abstract: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: August 20, 2019
    Assignee: DSM IP Assets B.V.
    Inventors: Stephen Robert Cherinko, Robert Cody Kertis, Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle, Nasrin Tabayehnejad, Krishna Raman, Neil Francis Leininger
  • Patent number: 10362794
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: July 30, 2019
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Publication number: 20190211369
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Application
    Filed: January 16, 2019
    Publication date: July 11, 2019
    Inventors: Kirk E. APT, James Casey LIPPMEIER, David SIMPSON, Jun WANG, James P. WYNN, Ross ZIRKLE
  • Patent number: 10272060
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: April 30, 2019
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Publication number: 20190000114
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: September 17, 2018
    Publication date: January 3, 2019
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Publication number: 20180295860
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: February 6, 2018
    Publication date: October 18, 2018
    Inventors: Kirk E. APT, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Publication number: 20180289652
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: April 6, 2018
    Publication date: October 11, 2018
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • Publication number: 20180282711
    Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.
    Type: Application
    Filed: June 12, 2018
    Publication date: October 4, 2018
    Inventors: Terence A. Walsh, Daniel J. Gachotte, Cory M. Larsen, Scott Bevan, P. Ann Owens-Merlo, James G. Metz, Ross Zirkle
  • Patent number: 10085465
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: October 2, 2018
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Publication number: 20180169049
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: February 6, 2018
    Publication date: June 21, 2018
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • Patent number: 9994828
    Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: June 12, 2018
    Assignees: Dow AgroSciences LLC, DSM IP Assets B.V.
    Inventors: Terence A. Walsh, Daniel J. Gachotte, Cory M. Larsen, Scott Bevan, P. Ann Owens-Merlo, James G. Metz, Ross Zirkle