Patents by Inventor Ross Zirkle

Ross Zirkle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF OMEGA 3 LONG CHAIN POLYUNSATURATED FATTY ACIDS IN OILSEED CROPS BY A THRAUSTOCHYTRID PUFA SYNTHASE
    Publication number: 20180282711
    Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.
    Type: Application
    Filed: June 12, 2018
    Publication date: October 4, 2018
    Inventors: Terence A. Walsh, Daniel J. Gachotte, Cory M. Larsen, Scott Bevan, P. Ann Owens-Merlo, James G. Metz, Ross Zirkle
  • Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
    Patent number: 10085465
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: October 2, 2018
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20180169049
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: February 6, 2018
    Publication date: June 21, 2018
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • Production of omega 3 long chain polyunsaturated fatty acids in oilseed crops by a thraustochytrid PUFA synthase
    Patent number: 9994828
    Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: June 12, 2018
    Assignees: Dow AgroSciences LLC, DSM IP Assets B.V.
    Inventors: Terence A. Walsh, Daniel J. Gachotte, Cory M. Larsen, Scott Bevan, P. Ann Owens-Merlo, James G. Metz, Ross Zirkle
  • EXTRACTION OF LIPID FROM CELLS AND PRODUCTS THEREFROM
    Publication number: 20180142183
    Abstract: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
    Type: Application
    Filed: January 19, 2018
    Publication date: May 24, 2018
    Inventors: Stephen Robert CHERINKO, Robert Cody KERTIS, Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE, Nasrin Tabayehnejad, Krishna Raman, Neil Francis Leininger
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9968578
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: May 15, 2018
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9924733
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: March 27, 2018
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • THRAUSTOCHYTRIDS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20180064138
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: October 23, 2017
    Publication date: March 8, 2018
    Inventors: Kirk E. APT, Joseph W. PFEIFER, III, Jon Milton Hansen, Paul Warren BEHRENS, Ross ZIRKLE, Tracey Lynn STAHL
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20170216239
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: April 7, 2017
    Publication date: August 3, 2017
    Inventors: Kirk E. APT, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, Tracey Lyy Stahl, Ross Zirkle
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20170164639
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: February 17, 2017
    Publication date: June 15, 2017
    Inventors: Kirk E. APT, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9668499
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: June 6, 2017
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • PROTEIN PRODUCTION IN MICROORGANISMS OF THE PHYLUM LABYRINTHULOMYCOTA
    Publication number: 20170145461
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Application
    Filed: November 3, 2016
    Publication date: May 25, 2017
    Inventors: Kirk E. APT, James Casey LIPPMEIER, David SIMPSON, Jun WANG, James P. WYNN, Ross ZIRKLE
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9649287
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: May 16, 2017
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9611488
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: April 4, 2017
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • POLYUNSATURATED FATTY ACID SYNTHASE NUCLEIC ACID MOLECULES AND POLYPEPTIDES, COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20170088841
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Application
    Filed: December 7, 2016
    Publication date: March 30, 2017
    Inventors: Kirk E. APT, Leslie Richter, David Simpson, Ross Zirkle
  • Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof
    Patent number: 9540666
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: January 10, 2017
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Leslie Richter, David Simpson, Ross Zirkle
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20160374976
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: June 30, 2016
    Publication date: December 29, 2016
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • Polypeptide for improving protein production in microorganisms of the phylum Labyrinthulomycota
    Patent number: 9518102
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: December 13, 2016
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • THRAUSTOCHYTRIDS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20160309748
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: July 13, 2016
    Publication date: October 27, 2016
    Inventors: Kirk E. APT, Joseph W. PFEIFER, III, Jon Milton Hansen, Paul Warren BEHRENS, Ross ZIRKLE, Tracey Lynn STAHL
  • Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9414612
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: August 16, 2016
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl