Patents by Inventor Roy K. Greenberg

Roy K. Greenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10413435
    Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. The indwelling guide wire are configured to receive the access sheaths. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate catheterization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: September 17, 2019
    Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLC
    Inventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik E. Rasmussen
  • Publication number: 20190279367
    Abstract: A computer implemented method for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure. A gradient field of a distance transformation is computed for the edge-detected dataset. A voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field. A trajectory within the tubular structure is computed based on the centerline.
    Type: Application
    Filed: May 17, 2019
    Publication date: September 12, 2019
    Inventors: Vikash R. Goel, Donald P. Greenberg, Roy K. Greenberg
  • Publication number: 20190239999
    Abstract: A stent graft (2) for placement in the thoracic arch of a patient has a first tubular body portion (6) with a first lumen therein for placement in the ascending aorta of a patient and a second tubular body portion (8) to extend along the thoracic arch and down the descending aorta. The second tubular body portion is of a lesser diameter than the first tubular body portion. There is a step portion (10) between the first body portion and the second body portion. The step portion is joined to and continuous with the first portion and the second portion. A first side of each of the first body portion, the step portion and the second body portion are substantially aligned so that there is a step (18) defined on a second side opposite to the first side of the body portion. There is an aperture (30) in the step portion and an internal tube (32) extending from the aperture towards the first body portion.
    Type: Application
    Filed: April 1, 2019
    Publication date: August 8, 2019
    Applicants: COOK MEDICAL TECHNOLOGIES LLC, THE CLEVELAND CLINIC FOUNDATION
    Inventors: David E. Hartley, Roy K. Greenberg, Krasnodar Ivancev, Michael Lawrence-Brown
  • Publication number: 20190192320
    Abstract: The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, a second perimeter attached to and surrounding the band of flexible material and a support frame disposed about a surface of the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. The support frame includes a plurality of support units having curved segments. The curved segments of the support units may be concave with respect to an exterior surface of the prosthesis.
    Type: Application
    Filed: March 5, 2019
    Publication date: June 27, 2019
    Inventors: Roy K. Greenberg, Blayne A. Roeder, Matthew S. Huser, William J. Havel
  • Patent number: 10304197
    Abstract: A computer implemented method for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure. A gradient field of a distance transformation is computed for the edge-detected dataset. A voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: May 28, 2019
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Vikash R. Goel, Donald P. Greenberg, Roy K. Greenberg
  • Publication number: 20190151073
    Abstract: An introduction arrangement for a fenestrated or branched stent graft intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.
    Type: Application
    Filed: January 24, 2019
    Publication date: May 23, 2019
    Applicants: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
  • Patent number: 10285799
    Abstract: A stent graft (2) for placement in the thoracic arch of a patient has a first tubular body portion (6) with a first lumen therein for placement in the ascending aorta of a patient and a second tubular body portion (8) to extend along the thoracic arch and down the descending aorta. The second tubular body portion is of a lesser diameter than the first tubular body portion. There is a step portion (10) between the first body portion and the second body portion. The step portion is joined to and continuous with the first portion and the second portion. A first side of each of the first body portion, the step portion and the second body portion are substantially aligned so that there is a step (18) defined on a second side opposite to the first side of the body portion. There is an aperture (30) in the step portion and an internal tube (32) extending from the aperture towards the first body portion.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: May 14, 2019
    Assignees: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: David E Hartley, Roy K Greenberg, Krasnodar Ivancev, Michael Lawrence-Brown
  • Patent number: 10265202
    Abstract: The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, a second perimeter attached to and surrounding the band of flexible material and a support frame disposed about a surface of the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. The support frame includes a plurality of support units having curved segments. The curved segments of the support units may be concave with respect to an exterior surface of the prosthesis.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 23, 2019
    Assignees: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Blayne A. Roeder, Matthew S. Huser, William J. Havel
  • Patent number: 10251743
    Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. Indwelling access sheaths are provided within auxiliary lumens of a pusher catheter and dilators are preloaded into the access sheaths along with the indwelling guide wire. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertisation of a side branch or target vessel through the fenestration or be used to stabilise the access sheath during catheterisation, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: April 9, 2019
    Assignees: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik E. Rasmussen
  • Patent number: 10201414
    Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (21) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: February 12, 2019
    Assignees: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
  • Publication number: 20190000607
    Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. The indwelling guide wire are configured to receive the access sheaths. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.
    Type: Application
    Filed: August 21, 2018
    Publication date: January 3, 2019
    Applicants: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik E. Rasmussen
  • Patent number: 10143576
    Abstract: A stent graft has a tubular body with a first bifurcation with first and second legs extending from the bifurcation. One of the legs has a further bifurcation to define a side arm. The stent graft can be deployed into the vasculature of a patient with the tubular body being in an aorta of the patient, a first leg extending down an iliac artery, a second leg being directed towards a contralateral iliac artery and the side arm directed to an internal artery of one of the iliac arteries. One of the legs can include a valved aperture to enable the placement of an indwelling catheter therethrough.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: December 4, 2018
    Assignees: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, David E. Hartley, Michael Lawrence-Brown
  • Patent number: 10092391
    Abstract: The present embodiments provide an endoluminal prosthesis having modular branches, and systems and methods for facilitating deployment of the endoluminal prosthesis. In one example, the endoluminal prosthesis comprises a graft including a bifurcated body of a biocompatible material. The bifurcated body includes distally extending limbs. Limb extensions can be longitudinally and circumferentially adjusted prior to mating with the limbs to enable an “off-the-shelf” prosthesis that can conform to various complex anatomy. When adjusted and mated, fenestrations in the limb extensions can align with branch vessels.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: October 9, 2018
    Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLC
    Inventors: Roy K. Greenberg, Blayne A. Roeder
  • Publication number: 20180243076
    Abstract: An endoluminal prosthesis comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch having a first branch lumen and a branch wall, and a second prosthetic branch having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.
    Type: Application
    Filed: April 13, 2018
    Publication date: August 30, 2018
    Applicant: The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Karl J. West, Davorin K. Skender, James C. Foster
  • Publication number: 20180174303
    Abstract: A computer implemented method for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure. A gradient field of a distance transformation is computed for the edge-detected dataset. A voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field.
    Type: Application
    Filed: January 30, 2018
    Publication date: June 21, 2018
    Inventors: Vikash R. Goel, Donald P. Greenberg, Roy K. Greenberg
  • Publication number: 20180153680
    Abstract: A branched and fenestrated prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. The branched and fenestrated prosthesis may include a plurality of branches and a plurality of fenestrations.
    Type: Application
    Filed: February 5, 2018
    Publication date: June 7, 2018
    Applicants: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Karl J. West, Timothy A. Resch, Blayne A. Roeder
  • Patent number: 9943400
    Abstract: An endoluminal prosthesis comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch having a first branch lumen and a branch wall, and a second prosthetic branch having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: April 17, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Karl J. West, Davorin K. Skender, James C. Foster
  • Patent number: 9922424
    Abstract: A computer implemented method for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure. A gradient field of a distance transformation is computed for the edge-detected dataset. A voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: March 20, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Vikash R. Goel, Donald P. Greenberg, Roy K. Greenberg
  • Patent number: 9883938
    Abstract: A system for facilitating deployment of an endoluminal prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. A wire segment may include a proximal portion positioned proximal of the proximal end opening and a distal portion positioned distal of the distal end opening. The wire segment extend through the fenestration and through the lumen of the branch in a preloaded configuration.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: February 6, 2018
    Assignees: COOK MEDICAL TECHNOLOGIES LLC, THE CLEVELAND CLINIC FOUNDATION
    Inventors: Roy K. Greenberg, Karl J. West, Timothy A. Resch, Blayne A. Roeder
  • Publication number: 20170325978
    Abstract: A stent graft has a tubular body with a first bifurcation with first and second legs extending from the bifurcation. One of the legs has a further bifurcation to define a side arm. The stent graft can be deployed into the vasculature of a patient with the tubular body being in an aorta of the patient, a first leg extending down an iliac artery, a second leg being directed towards a contralateral iliac artery and the side arm directed to an internal artery of one of the iliac arteries. One of the legs can include a valved aperture to enable the placement of an indwelling catheter therethrough.
    Type: Application
    Filed: July 17, 2017
    Publication date: November 16, 2017
    Applicants: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, David E. Hartley, Michael Lawrence-Brown