Patents by Inventor Rudolf H. Hanko

Rudolf H. Hanko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives
    Patent number: 5834481
    Abstract: Heterotricyclically substituted phenyl-cyclohexanecarboxylic acid derivatives are prepared by reacting the heterocyclic compounds with cyclohexanecarboxylic acid derivatives which are substituted by benzyl halide radicals. The compounds can be employed as active compounds in medicaments.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: November 10, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich E. Muller, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives
    Patent number: 5708003
    Abstract: Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives are prepared by reacting the heterocyclic compounds with cyclohexanecarboxylic acid derivatives which are substituted by benzyl halide radicals. The compounds can be employed as active compounds in medicaments.
    Type: Grant
    Filed: September 8, 1995
    Date of Patent: January 13, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich E. Muller, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Substituted imidazo[4,5-b]pyridines and benzimidazoles
    Patent number: 5527809
    Abstract: Substituted imidazo[4,5-b]pyridines and benzimidazoles are prepared by reacting imidazo[4,5-b]pyridines or benzimidazoles with appropriately substituted benzyl halides. The substituted imidazo[4,5-b]pyridines or benzimidazoles can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: June 18, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Matthias Muller-Gliemann, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Ulrich E. Muller, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Imidazolyl-substituted cyclohexane derivatives
    Patent number: 5508299
    Abstract: Imidazolyl-substituted cyclohexane derivatives are prepared by reacting appropriate cyclohexane derivatives with substituted imidazoles and subsequent variation of the substituents.The imidazolyl-substituted cyclohexane derivatives can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
    Type: Grant
    Filed: June 21, 1993
    Date of Patent: April 16, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich E. Muller, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Andreas Knorr, Johannes-Peter Stasch, Stefan Wohlfeil
  • Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives
    Patent number: 5478836
    Abstract: Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives are prepared by reacting the heterocyclic compounds with cyclohexanecarboxylic acid derivatives which are substituted by benzyl halide radicals. The compounds can be employed as active compounds in medicaments.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: December 26, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich E. Muller, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Imidazolyl-substituted phenylacetic acid prolinamides
    Patent number: 5459156
    Abstract: Imidazolyl-substituted phenylacetic acid prolinamides are prepared by reacting corresponding imidazolyl-substituted phenylacetic acids with prolines. The imidazolyl-substituted phenylacetic acid prolinamides can be used as active compounds in medicaments, preferably for the treatment of hypertension and atherosclerosis.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: October 17, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Matthias Muller-Gliemann, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Ulrich E. Muller, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives
    Patent number: 5414008
    Abstract: Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives are prepared by reacting appropriate benzyl compounds with imidazoles and optionally varying the substituents. The imidazolyl-substituted phenylpropionic and cinnamic acid derivatives can be used as active compounds in medicaments, in particular in the treatment of arterial hypertension and atherosclerosis.
    Type: Grant
    Filed: June 21, 1993
    Date of Patent: May 9, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich E. Muller, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Andreas Knorr, Johannes-Peter Stasch, Stefan Wohlfeil
  • Biphenylmethyl-substituted pyridones
    Patent number: 5407942
    Abstract: Biphenylmethyl-substituted pyridones are prepared by reaction of pyridones with appropriate biphenylmethyl compounds.The biphenylmethyl-substituted pyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
    Type: Grant
    Filed: May 5, 1993
    Date of Patent: April 18, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Ulrich E. Muller, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch
  • Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives
    Patent number: 5395840
    Abstract: Heterocyclically substituted phenyl-cyclohexanecarboxylic acid derivatives are prepared by reacting appropriate heterocyclic compounds with cyclohexanebenzyl halides.The compounds can be employed as active compounds in medicaments for the treatment of arterial hypertension and atherosclerosis.
    Type: Grant
    Filed: February 8, 1994
    Date of Patent: March 7, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich E. Muller, Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Matthias Muller-Gliemann, Martin Beuck, Stanisiav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Sulfonylbenzyl-substituted benzo- and pyridopyridones
    Patent number: 5354749
    Abstract: Sulfonylbenzyl-substituted benzo- and pyridopyridones are prepared by reacting corresponding benzo- and pyridopyridones with sulphonylbenzyl compounds. The sulphonylbenzyl-substituted benzo- and pyridopyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hyper tension and atherosclerosis.
    Type: Grant
    Filed: May 5, 1993
    Date of Patent: October 11, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Dressel, Peter Fey, Rudolf H. Hanko, Walter Hubsch, Thomas Kramer, Ulrich E. Muller, Matthias Muller-Gliemann, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch
  • Proline derivatives and compositions for their use as inhibitors of HIV protease
    Patent number: 5296604
    Abstract: The present disclosure describes novel peptidomimetic compounds which contain a novel class of isosteres and which inhibit the proteolytic activity of HIV protease and further describes therapeutic compositions comprising said compounds, a method of treatment for patients having the AIDS virus involving administering a therapeutically effective amount of the novel compounds of the present invention, and a method of preparation for said isosteres.
    Type: Grant
    Filed: May 15, 1992
    Date of Patent: March 22, 1994
    Assignee: Miles Inc.
    Inventors: Rudolf H. Hanko, Thomas Gould, Paul P. Tamburini