Patents by Inventor RUSTOM FALAHATI
RUSTOM FALAHATI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230331854Abstract: The invention provides methods and compositions for the prevention and treatment of advanced systemic mastocytosis such as systemic mastocytosis with an associated hematologic non-mast-cell lineage disease (SM-AHNMD). In particular, the invention provides methods for the prevention and treatment of advanced systemic mastocytosis through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of advanced systemic mastocytosis such as SM-AHNMD.Type: ApplicationFiled: October 26, 2022Publication date: October 19, 2023Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI
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Publication number: 20230303686Abstract: The invention provides methods and compositions for the prevention or treatment of fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis. In particular, the invention provides methods for the prevention or treatment of fibrotic diseases and pre-fibrotic diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention or treatment fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis.Type: ApplicationFiled: October 21, 2022Publication date: September 28, 2023Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI, Bradford Andrew YOUNGBLOOD
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Publication number: 20220331412Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.Type: ApplicationFiled: January 26, 2022Publication date: October 20, 2022Applicant: Allakos Inc.Inventors: Christopher R. BEBBINGTON, Rustom FALAHATI, Carolina Rita SOUSA FERNANDES, David John MATTHEWS, Nenad TOMASEVIC, Jason WILLIAMS, John LEUNG
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Publication number: 20210107977Abstract: The invention provides methods and compositions for the prevention or treatment of fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis. In particular, the invention provides methods for the prevention or treatment of fibrotic diseases and pre-fibrotic diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention or treatment fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis.Type: ApplicationFiled: July 31, 2020Publication date: April 15, 2021Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI, Bradford Andrew YOUNGBLOOD
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Patent number: 10774145Abstract: The invention provides methods and compositions for the prevention or treatment of fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis. In particular, the invention provides methods for the prevention or treatment of fibrotic diseases and pre-fibrotic diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention or treatment fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis.Type: GrantFiled: June 16, 2016Date of Patent: September 15, 2020Assignee: Allakos Inc.Inventors: Christopher Robert Bebbington, Nenad Tomasevic, Rustom Falahati, Bradford Andrew Youngblood
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Publication number: 20200181270Abstract: The invention provides methods and compositions for the prevention and treatment of advanced systemic mastocytosis such as systemic mastocytosis with an associated hematologic non-mast-cell lineage disease (SM-AHNMD). In particular, the invention provides methods for the prevention and treatment of advanced systemic mastocytosis through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of advanced systemic mastocytosis such as SM-AHNMD.Type: ApplicationFiled: February 20, 2020Publication date: June 11, 2020Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI
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Patent number: 10604577Abstract: The invention provides methods and compositions for the prevention and treatment of advanced systemic mastocytosis such as systemic mastocytosis with an associated hematologic non-mast-cell lineage disease (SM-AHNMD). In particular, the invention provides methods for the prevention and treatment of advanced systemic mastocytosis through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of advanced systemic mastocytosis such as SM-AHNMD.Type: GrantFiled: October 20, 2016Date of Patent: March 31, 2020Assignee: Allakos Inc.Inventors: Christopher Robert Bebbington, Nenad Tomasevic, Rustom Falahati
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Publication number: 20200054723Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.Type: ApplicationFiled: May 17, 2019Publication date: February 20, 2020Applicant: Allakos Inc.Inventors: Christopher R. BEBBINGTON, Rustom FALAHATI, Carolina Rita SOUSA FERNANDES, David John MATTHEWS, Nenad TOMASEVIC, Jason WILLIAMS, John LEUNG
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Patent number: 10183996Abstract: The invention provides methods and compositions for the prevention and treatment of Siglec-8 associated diseases such as chronic rhino sinusitis with concomitant asthma and aspirin-exacerbated respiratory disease. In particular, the invention provides methods for the prevention and treatment of Siglec-8 associated diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of Siglec-8 associated diseases such as chronic rhinosinusitis with concomitant asthma and aspirin-exacerbated respiratory disease.Type: GrantFiled: February 27, 2015Date of Patent: January 22, 2019Assignee: Allakos Inc.Inventors: Christopher Robert Bebbington, Nenad Tomasevic, Rustom Falahati
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Publication number: 20180179279Abstract: The invention provides methods and compositions for the prevention or treatment of fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis. In particular, the invention provides methods for the prevention or treatment of fibrotic diseases and pre-fibrotic diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention or treatment fibrotic diseases such as idiopathic pulmonary fibrosis and pre-fibrotic diseases such as chronic hypersensitivity pneumonitis.Type: ApplicationFiled: June 16, 2016Publication date: June 28, 2018Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI, Bradford Andrew YOUNGBLOOD
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Publication number: 20170209556Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.Type: ApplicationFiled: December 7, 2016Publication date: July 27, 2017Applicant: Allakos Inc.Inventors: Christopher R. BEBBINGTON, Rustom FALAHATI, Carolina Rita SOUSA FERNANDES, David John MATTHEWS, Nenad TOMASEVIC, Jason WILLIAMS, John LEUNG
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Publication number: 20170114138Abstract: The invention provides methods and compositions for the prevention and treatment of advanced systemic mastocytosis such as systemic mastocytosis with an associated hematologic non-mast-cell lineage disease (SM-AHNMD). In particular, the invention provides methods for the prevention and treatment of advanced systemic mastocytosis through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of advanced systemic mastocytosis such as SM-AHNMD.Type: ApplicationFiled: October 20, 2016Publication date: April 27, 2017Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI
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Publication number: 20170073413Abstract: The invention provides methods and compositions for the prevention and treatment of Siglec-8 associated diseases such as chronic rhino sinusitis with concomitant asthma and aspirin-exacerbated respiratory disease. In particular, the invention provides methods for the prevention and treatment of Siglec-8 associated diseases through administration of antibodies or agonists that bind to human Siglec-8 or compositions comprising said antibodies or agonists. The invention also provides articles of manufacture or kits comprising antibodies or agonists that bind to human Siglec-8 for the prevention and treatment of Siglec-8 associated diseases such as chronic rhinosinusitis with concomitant asthma and aspirin-exacerbated respiratory disease.Type: ApplicationFiled: February 27, 2015Publication date: March 16, 2017Inventors: Christopher Robert BEBBINGTON, Nenad TOMASEVIC, Rustom FALAHATI
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Patent number: 9546215Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.Type: GrantFiled: December 9, 2014Date of Patent: January 17, 2017Assignee: ALLAKOS INC.Inventors: Christopher R. Bebbington, Rustom Falahati, Carolina Rita Sousa Fernandes, David John Matthews, Nenad Tomasevic, Jason Williams, John Leung
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Publication number: 20150203578Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.Type: ApplicationFiled: December 9, 2014Publication date: July 23, 2015Applicant: ALLAKOS INC.Inventors: CHRISTOPHER R. BEBBINGTON, RUSTOM FALAHATI, CAROLINA RITA SOUSA FERNANDES, DAVID JOHN MATTHEWS, NENAD TOMASEVIC, JASON WILLIAMS, JOHN LEUNG