Patents by Inventor Ruthrotha Selvi Bharatha Vikru

Ruthrotha Selvi Bharatha Vikru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intrinsically fluorescent carbon nanospheres and a process thereof
    Patent number: 9034387
    Abstract: The present invention provides solution to the problem involved in delivery of active molecules to nucleus. More particularly, the invention provides intrinsically fluorescent and inherently surface functionalized carbon nanospheres which are non-toxic. Also, these carbon nanospheres [CSP] were adsorbed with CTPB [CSP-CTPB] and the adsorbed CSP-CTPB are permeable to cells with nuclear targeting ability. In addition, the present invention provides a composition, a process to prepare the composition comprising CSP with adsorbed active/therapeutic molecules. Further, the instant invention provides a method for delivering active molecules inside a cell nucleus.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: May 19, 2015
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Tapas Kumar Kundu, Eswaramoorthy Muthusamy, Sr., Ruthrotha Selvi Bharatha Vikru, Dinesh Jagadeesan
  • Site-specific inhibitors of histone methyltransferase (HMTASE) and process of preparation thereof
    Patent number: 8003698
    Abstract: The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural formula Ia, where R1 and R1 is —OCH3, R2 and R2 is —OH; a process of preparation of compound of structural formula Ib, where R1 and R1 is —OCH3, R2 and R2 is —OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is —OH, R2 and R2 is —OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: August 23, 2011
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Tapas Kumar Kundu, Ruthrotha Selvi Bharatha Vikru, Hari Kishore Annavarapu, Mantelingu Kempegowda
  • Site-Specific Inhibitors of Histone Methyltransferase (HMTASE) and Process of Preparation Thereof
    Publication number: 20110087043
    Abstract: The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural formula Ia, where R1 and R1 is —OCH3, R2 and R2 is —OH; a process of preparation of compound of structural formula Ib, where R1 and R1 is —OCH3, R2 and R2 is —OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is —OH, R2 and R2 is —OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 14, 2011
    Inventors: Tapas Kumar Kundu, Ruthrotha Selvi Bharatha Vikru, Hari Kishore Annavarapu, Mantelingu Kempegowda
  • Site-specific inhibitors of histone methyltransferase [HMTase] and process of preparation thereof
    Patent number: 7875741
    Abstract: The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural formula Ia, where R1 and R1 is —OCH3, R2 and R2 is —OH; a process of preparation of compound of structural formula Ib, where R1 and R1 is —OCH3, R2 and R2 is —OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is —OH, R2 and R2 is —OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: January 25, 2011
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Tapas Kumar Kundu, Ruthrotha Selvi Bharatha Vikru, Hari Kishore Annavarapu, Mantelingu Kempegowda
  • Site-Specific Inhibitors of Histone Methyltransferase [HMTASE] and Process of Preparation Thereof
    Publication number: 20100292498
    Abstract: The present invention relates to compounds of structural formula (I) as site-specific inhibitor of histone methyl-transferase, where R1 and R1 is —OCH or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural formula (Ia), where R1 and R1 is —OCH, R2 and R2 is —OH; a process of preparation of compound of structural formula (Ib), where R1 and R1 is —OCH, R2 and R2 is —OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is —OH, R2 and R2 is —OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof.
    Type: Application
    Filed: June 26, 2007
    Publication date: November 18, 2010
    Applicant: Jawaharlal Nehru Centre For Advanced Scientific Research
    Inventors: Tapas Kumar Kundu, Ruthrotha Selvi Bharatha Vikru, Hari Kishore Annavarapu, Matelingu Kempegowda
  • INTRINSCIALLY FLUORESCENT CARBON NANOSPHERES AND A PROCESS THEREOF
    Publication number: 20100215760
    Abstract: The present invention provides solution to the problem involved in delivery of active molecules to nucleus. More particularly, the invention provides intrinsically fluorescent and inherently surface functionalized carbon nanospheres which are non-toxic. Also, these carbon nanospheres [CSP] were adsorbed with CTPB [CSP-CTPB] and the adsorbed CSP-CTPB are permeable to cells with nuclear targeting ability. In addition, the present invention provides a composition, a process to prepare the composition comprising CSP with adsorbed active/therapeutic molecules. Further, the instant invention provides a method for delivering active molecules inside a cell nucleus.
    Type: Application
    Filed: September 30, 2008
    Publication date: August 26, 2010
    Applicant: JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH
    Inventors: Tapas Kumar Kundu, Eswaramoorthy Muthusamy, Ruthrotha Selvi Bharatha Vikru, Dinesh Jagadeesan