Abstract: A method includes: obtaining, by a computer, subject response data including audio data, video data, or audio-video data of a subject's response to one or more stimuli presented to the subject over a defined time period; extracting at least one subject descriptor from the subject response data as a function of time, the at least one subject descriptor including data characterizing involuntary or voluntary action of the subject in response to the one or more stimuli; deriving, from the at least one subject descriptor, a first biomarker characterizing a behavior of the subject in response to the one or more stimuli, in which a value of the first biomarker is indicative of a severity of a disease in the subject; and outputting a disease severity level for the disease as a function of the value of the first biomarker.

Abstract: A computer-implemented method includes obtaining a video of a subject, the video including a plurality of frames; generating, based on the plurality of frames, a plurality of optical flows; and encoding the plurality of optical flows using an autoencoder to obtain a movement-based biomarker value of the subject.

Abstract: A computer-implemented method includes obtaining a video of a subject, the video including a plurality of frames; generating, based on the plurality of frames, a plurality of optical flows; and encoding the plurality of optical flows using an autoencoder to obtain a movement-based biomarker value of the subject.

Abstract: A method includes: obtaining, by a computer, subject response data including audio data, video data, or audio-video data of a subject's response to one or more stimuli presented to the subject over a defined time period; extracting at least one subject descriptor from the subject response data as a function of time, the at least one subject descriptor including data characterizing involuntary or voluntary action of the subject in response to the one or more stimuli; deriving, from the at least one subject descriptor, a first biomarker characterizing a behavior of the subject in response to the one or more stimuli, in which a value of the first biomarker is indicative of a severity of a disease in the subject; and outputting a disease severity level for the disease as a function of the value of the first biomarker.

Abstract: Surgical trauma training simulator system including replaceable trauma module structured to mimic a portion of human anatomy and, in particular, a prosthetic anatomical structure containing a periorbital structure that includes an eye-lid and an eye globe in cooperation with a drive mechanism. The system is structured to provide, in operation, an event-driven surgical gesture recognition-based tracking of the simulation of the surgical procedure by the trainee and, in absence of expert trainer, provide visual feedback comparing the tracked simulation with correct sequence of steps of such procedure.

Abstract: Surgical trauma training simulator system including replaceable trauma module structured to mimic a portion of human anatomy and, in particular, a prosthetic anatomical structure containing a periorbital structure that includes an eye-lid and an eye globe in cooperation with a drive mechanism. The system is structured to provide, in operation, an event-driven surgical gesture recognition-based tracking of the simulation of the surgical procedure by the trainee and, in absence of expert trainer, provide visual feedback comparing the tracked simulation with correct sequence of steps of such procedure.

Abstract: Method and apparatus to provide simulation of a human casualty. In one embodiment an autonomous casualty simulator includes a processing module having a scenario progression controller and a physiological modeling system to receive sensor input and to control effectors. The autonomous casualty simulator can be contained in a nominal human mannequin form.

Abstract: Method and apparatus to provide simulation of a human casualty. In one embodiment an autonomous casualty simulator includes a processing module having a scenario progression controller and a physiological modeling system to receive sensor input and to control effectors. The autonomous casualty simulator can be contained in a nominal human mannequin form.

Abstract: Method and apparatus to provide simulation of a human casualty. In one embodiment an autonomous casualty simulator includes a processing module having a scenario progression controller and a physiological modeling system to receive sensor input and to control effectors. The autonomous casualty simulator can be contained in a nominal human mannequin form.

Abstract: Method and apparatus to provide simulation of a human casualty. In one embodiment an autonomous casualty simulator includes a processing module having a scenario progression controller and a physiological modeling system to receive sensor input and to control effectors. The autonomous casualty simulator can be contained in a nominal human mannequin form.