Patents by Inventor Ryuichi Nakagami

Ryuichi Nakagami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200251617
    Abstract: A light-emitting device includes a base member including a first lead, a second lead, and a securing member securing the first lead and the second lead, a light-emitting element mounted on an upper surface of the base member, a frame disposed on the upper surface of the base member to surround the light-emitting element, a first member covering at least a portion of an upper surface of the securing member exposed at an outer peripheral side of the frame in a top view, the first member being in contact with an outer lateral surface of the frame and containing a reflective material, and a second member covering the light-emitting element, the frame, and the first member. The first member has an inclined region in a cross-sectional view. A maximum height of the inclined region is less than a height of an upper end of the frame.
    Type: Application
    Filed: January 29, 2020
    Publication date: August 6, 2020
    Applicant: NICHIA CORPORATION
    Inventors: Hiroaki UKAWA, Ryuichi NAKAGAMI, Ryuji MURANAKA
  • Patent number: 10695420
    Abstract: The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains (I) the antigenic peptide, and (II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74-87 or 130-138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, wherein the antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: June 30, 2020
    Assignees: ANGES, INC., OSAKA UNIVERSITY, DS PHARMA ANIMAL HEALTH CO., LTD.
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Hideki Tomioka, Kenji Naohara
  • Publication number: 20200168776
    Abstract: A light-emitting device includes: a base body comprising a resin member, a first lead, and a second lead, wherein the first lead and the second lead are supported by the resin member; a light-emitting element mounted on an upper surface of the base body; a resin frame located on the upper surface of the base body, surrounding the light-emitting element; and a first resin located inside the resin frame to cover a part of side surfaces of the light-emitting element, a part of an inner side surface of the resin frame, and the upper surface of the base body, wherein the first resin includes: a reflection material layer that contains a reflection material, and a resin layer that is located on an upper surface of the reflective material layer and does not contain the reflective material.
    Type: Application
    Filed: November 19, 2019
    Publication date: May 28, 2020
    Applicant: NICHIA CORPORATION
    Inventors: Hiroaki UKAWA, Ryuichi NAKAGAMI, Ryuji MURANAKA
  • Publication number: 20200061222
    Abstract: A light-emitting device includes a light-emitting element with a peak emission wavelength in a range of 400 nm to 410 nm and a fluorescent member that contains a first phosphor with a peak emission wavelength in a range of 440 nm to 470 nm containing a Eu-activated alkaline-earth phosphate that contains Cl in a composition, a second phosphor with a peak emission wavelength in a range of 500 nm to 530 nm containing a Eu-activated halogen-containing alkaline-earth silicate, a third phosphor with a peak emission wavelength in a range of 530 nm to 600 nm containing a Ce-activated rare-earth aluminate, and a fourth phosphor with a peak emission wavelength in a range of 600 nm to 660 nm containing a Eu-activated silicon nitride containing Al and at least one of Sr and Ca in a composition.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Applicant: NICHIA CORPORATION
    Inventors: Hiroaki UKAWA, Ryuichi NAKAGAMI
  • Patent number: 10543261
    Abstract: The present invention provides a therapeutic or prophylactic agent for cancer, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of VEGF and/or a specific epitope of angiopoietin-2, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: January 28, 2020
    Assignees: Osaka University, AnGes, Inc.
    Inventors: Hironori Nakagami, Mariko Kyutoku, Ryuichi Morishita, Hideki Tomioka
  • Publication number: 20200023045
    Abstract: Provided is an immunogenic composition comprising an antigenic peptide capable of inducing production of a neutralizing antibody against S100A9 and a carrier protein. The immunogenic composition can be used as a highly safe antithrombotic vaccine having antithrombotic effect without a long-term bleeding risk and is useful for the prevention of a disease associated with thrombus formation in which platelet aggregation is involved, particularly for the prevention of recurrent ischemic stroke.
    Type: Application
    Filed: February 20, 2018
    Publication date: January 23, 2020
    Applicants: OSAKA UNIVERSITY, FUNPEP CO., LTD.
    Inventors: Munehisa SHIMAMURA, Tomohiro KAWANO, Hironori NAKAGAMI, Ryuichi MORISHITA, Hideki MOCHIZUKI, Akiko TENMA, Takako EHARA
  • Patent number: 10517926
    Abstract: Provided is an oligopeptide having preventive and therapeutic effects on infarction diseases. The oligopeptide contains a DE loop sequence of RANKL protein, and has inhibitory activity on proinflammatory cytokine secretion from cells.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: December 31, 2019
    Assignee: Osaka University
    Inventors: Munehisa Shimamura, Hironori Nakagami, Hitomi Kurinami, Ryuichi Morishita
  • Publication number: 20190365859
    Abstract: The present invention provides a preventive or therapeutic agent for an inflammatory skin disease, such as psoriasis, the agent comprising an oligopeptide as an active ingredient. More specifically, the invention provides a preventive or therapeutic agent for an inflammatory skin disease, the agent comprising an oligopeptide consisting of an amino acid sequence containing a DE loop sequence of RANKL protein and a ?-strand D sequence of RANKL protein placed adjacent to the N-terminal side of the DE loop sequence.
    Type: Application
    Filed: November 7, 2017
    Publication date: December 5, 2019
    Inventors: Munehisa Shimamura, Hironori Nakagami, Yuka Ikeda, Ryuichi Morishita, Hiroshi Koriyama
  • Patent number: 10493175
    Abstract: A light-emitting device includes a light-emitting element with a peak emission wavelength in a range of 400 nm to 410 nm and a fluorescent member that contains a first phosphor with a peak emission wavelength in a range of 440 nm to 470 nm containing a Eu-activated alkaline-earth phosphate that contains Cl in a composition, a second phosphor with a peak emission wavelength in a range of 500 nm to 530 nm containing a Eu-activated halogen-containing alkaline-earth silicate, a third phosphor with a peak emission wavelength in a range of 530 nm to 600 nm containing a Ce-activated rare-earth aluminate, and a fourth phosphor with a peak emission wavelength in a range of 600 nm to 660 nm containing a Eu-activated silicon nitride containing Al and at least one of Sr and Ca in a composition.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: December 3, 2019
    Assignee: NICHIA CORPORATION
    Inventors: Hiroaki Ukawa, Ryuichi Nakagami
  • Patent number: 10463592
    Abstract: An object of the present invention to discover a short peptide having an anti-aging effect and to provide a novel anti-aging agent comprising the peptide as an active ingredient. The inventors have discovered that a peptide consisting of an amino acid sequence ELKLIFLHRLKRLRKRLKRK (SEQ ID NO: 1) or a partial sequence thereof and having one or more effects selected from the group consisting of promoting fibroblast growth, promoting hyaluronic acid production and contracting a collagen gel, or a derivative or salt of the peptide is useful as an active ingredient of an anti-aging agent.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: November 5, 2019
    Assignee: Osaka University
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hideki Tomioka, Akiko Tenma
  • Publication number: 20190321444
    Abstract: Described herein is the discovery that HGFs activate the growth and migration of lymphatic endothelial cells and thereby promote lymphangiogenesis. The present invention is based on this finding, and provides lymphangiogenesis-promoting agents comprising as active ingredients HGFs, or proteins or compounds functionally equivalent thereto. Based on the finding described above, the present invention also provides methods for promoting lymphangiogenesis which comprise the step of locally administering HGFs or proteins functionally equivalent thereto to affected areas in patients with lymphedema.
    Type: Application
    Filed: January 3, 2019
    Publication date: October 24, 2019
    Applicant: AnGes, Inc.
    Inventors: RYUICHI MORISHITA, Yasufumi Kaneda, Hironori Nakagami, Yukihiro Saito
  • Publication number: 20190115512
    Abstract: A light emitting device includes: a base member including: a first lead, a second lead, and a supporting member, the base member having an upper surface including a first surface, which is a surface of the first lead, a second surface, which is a surface of the second lead, and a third surface, which is a surface of the supporting member; a light emitting element located on the first surface; a protective element located on the second surface; a wire having a first end connected to the first surface, and a second end connected to a terminal electrode of the protective element; a resin frame located on the upper surface of the base member; a first resin part surrounded by the resin frame and covering the light emitting element and the first end of the wire; and a second resin part covering the resin frame and the first resin part.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 18, 2019
    Applicant: Nichia Corporation
    Inventors: Hiroaki UKAWA, Ryuichi NAKAGAMI
  • Publication number: 20190091355
    Abstract: A light-emitting device includes a light-emitting element with a peak emission wavelength in a range of 400 nm to 410 nm and a fluorescent member that contains a first phosphor with a peak emission wavelength in a range of 440 nm to 470 nm containing a Eu-activated alkaline-earth phosphate that contains Cl in a composition, a second phosphor with a peak emission wavelength in a range of 500 nm to 530 nm containing a Eu-activated halogen-containing alkaline-earth silicate, a third phosphor with a peak emission wavelength in a range of 530 nm to 600 nm containing a Ce-activated rare-earth aluminate, and a fourth phosphor with a peak emission wavelength in a range of 600 nm to 660 nm containing a Eu-activated silicon nitride containing Al and at least one of Sr and Ca in a composition.
    Type: Application
    Filed: September 26, 2018
    Publication date: March 28, 2019
    Applicant: NICHIA CORPORATION
    Inventors: Hiroaki UKAWA, Ryuichi NAKAGAMI
  • Patent number: 10021789
    Abstract: An object is to provide a laminated polyimide substrate, and a method for the production thereof, in which various properties are ensured and/or provided by effectively controlling changes over time under stringent conditions, while ensuring sufficient adhesion between a polyimide film and metal layer. A laminated polyimide substrate comprises a polyimide layer, an alkali-treated layer derived from the polyimide layer, and a metal layer, arranged in that order, wherein the alkali-treated layer contains an anionic functional group, and is a laminated structure having a layer containing a metal catalyst arranged on the metal layer side and a layer containing a complex of the metal catalyst arranged on the polyimide layer side.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: July 10, 2018
    Assignee: EBARA-UDYLITE CO., LTD.
    Inventors: Shinya Ochi, Ryuichi Nakagami, Makoto Kohtoku, Mika Hamada
  • Publication number: 20100189974
    Abstract: An object is to provide a laminated polyimide substrate, and a method for the production thereof, in which various properties are ensured and/or provided by effectively controlling changes over time under stringent conditions, while ensuring sufficient adhesion between a polyimide film and metal layer. A laminated polyimide substrate comprising a polyimide layer, an alkali-treated layer derived from the polyimide layer, and a metal layer, arranged in that order, wherein the alkali-treated layer contains an anionic functional group, and is a laminated structure having a layer containing a metal catalyst arranged on the metal layer side and a layer containing a complex of the metal catalyst arranged on the polyimide layer side.
    Type: Application
    Filed: June 26, 2008
    Publication date: July 29, 2010
    Inventors: Shinya Ochi, Ryuichi Nakagami, Makoto Kohtoku, Mika Hamada
  • Patent number: 7282255
    Abstract: The present invention relates to a flexible printed circuit board which has extremely high adhesion performance and on which very fine circuit patterns can be formed by etching, and to a method for producing the same. In the present invention, in the flexible printed circuit board wherein a copper thin film made of copper or an alloy containing primarily copper is directly formed on at least one side of a plastic film substrate, and copper is formed further on the copper thin film by the electrolytic plating method, the above-mentioned copper thin film has a two-layer structure in which a layer including at least a crystalline structure is formed on the surface side thereof, and the X-ray relative intensity ratio between crystal lattice plane indices (200)/(111) in the above-mentioned crystalline structure is 0.1 or less.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: October 16, 2007
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Kouichi Hiranaka, Ryuichi Nakagami, Mitsuhiro Fukuoka, Motohiro Yamashita
  • Publication number: 20050174722
    Abstract: The present invention relates to a flexible printed circuit board which has extremely high adhesion performance and on which very fine circuit patterns can be formed by etching, and to a method for producing the same. In the present invention, in the flexible printed circuit board wherein a copper thin film made of copper or an alloy containing primarily copper is directly formed on at least one side of a plastic film substrate, and copper is formed further on the copper thin film by the electrolytic plating method, the above-mentioned copper thin film has a two-layer structure in which a layer including at least a crystalline structure is formed on the surface side thereof, and the X-ray relative intensity ratio between crystal lattice plane indices (200)/(111) in the above-mentioned crystalline structure is 0.1 or less.
    Type: Application
    Filed: April 17, 2003
    Publication date: August 11, 2005
    Applicant: Matsushita Electric Industrial Co. Ltd.
    Inventors: Kouichi Hiranaka, Ryuichi Nakagami, Mitsuhiro Fukuoka, Motohiro Yamashita