Patents by Inventor S. George Kottayil

S. George Kottayil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9241935
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: January 26, 2016
    Assignee: Insys Pharma, Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Publication number: 20150297538
    Abstract: A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously over a prolonged time period is disclosed. In certain embodiments, the dose is intravenously administered in a time period from about 10 minutes to about 3 hours, preferably from about 10 minutes to about 30 minutes. In other embodiments, intravenous doses are administered at suitable time intervals over a time period from about 3 hours to 48 hours.
    Type: Application
    Filed: November 21, 2014
    Publication date: October 22, 2015
    Inventors: S. George KOTTAYIL, Jeffrey H. PING
  • Publication number: 20150258045
    Abstract: A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously over a prolonged time period is disclosed. In certain embodiments, the dose is intravenously administered in a time period from about 10 minutes to about 3 hours, preferably from about 10 minutes to about 30 minutes. In other embodiments, intravenous doses are administered at suitable time intervals over a time period from about 3 hours to 48 hours.
    Type: Application
    Filed: May 15, 2015
    Publication date: September 17, 2015
    Inventors: S. George Kottayil, Jeffrey H. Ping
  • Patent number: 8895622
    Abstract: A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously over a prolonged time period is disclosed. In certain embodiments, the dose is intravenously administered in a time period from about 10 minutes to about 3 hours, preferably from about 10 minutes to about 30 minutes. In other embodiments, intravenous doses are administered at suitable time intervals over a time period from about 3 hours to 48 hours.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: November 25, 2014
    Assignee: Revogenex Ireland Ltd.
    Inventors: S. George Kottayil, Jeffrey H. Ping
  • Publication number: 20140343288
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Application
    Filed: July 31, 2014
    Publication date: November 20, 2014
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Publication number: 20140343100
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Application
    Filed: July 31, 2014
    Publication date: November 20, 2014
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Patent number: 8835460
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: September 16, 2014
    Assignee: Insys Therapeutics, Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Patent number: 8835459
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: September 16, 2014
    Assignee: Insys Therapeutics, Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Patent number: 8628796
    Abstract: A room temperature stable cannabinoid formulation is disclosed. In preferred embodiments, the cannabinoid formulation is dronabinol in an oil-based carrier contained within a hard gelatin capsule.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: January 14, 2014
    Assignee: Insys Therapeutics, Inc.
    Inventors: S. George Kottayil, Zhongyuan Zhu, Venkat R. Goskonda
  • Publication number: 20130327321
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Application
    Filed: May 15, 2013
    Publication date: December 12, 2013
    Applicant: Insys Therapeutics, Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Publication number: 20130296368
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Application
    Filed: May 15, 2013
    Publication date: November 7, 2013
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Patent number: 8486972
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: July 16, 2013
    Assignee: Insys Therapeutics, Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Neha Parikh, Linet Kattookaran
  • Patent number: 8486973
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: July 16, 2013
    Assignee: Insys Therapeutics, Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Publication number: 20130005821
    Abstract: A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously over a prolonged time period is disclosed. In certain embodiments, the dose is intravenously administered in a time period from about 10 minutes to about 3 hours, preferably from about 10 minutes to about 30 minutes. In other embodiments, intravenous doses are administered at suitable time intervals over a time period from about 3 hours to 48 hours.
    Type: Application
    Filed: April 12, 2012
    Publication date: January 3, 2013
    Applicant: Revogenex Inc.
    Inventors: S. George Kottayil, Jeffrey H. Ping
  • Publication number: 20090181080
    Abstract: A room temperature stable aqueous cannabinoid formulation is disclosed. In preferred embodiments, the cannabinoid formulation comprises dronabinol in a mixture of buffer solution, and organic cosolvents such as ethanol, propylene glycol and polyethylene glycol.
    Type: Application
    Filed: August 6, 2008
    Publication date: July 16, 2009
    Applicant: Insys Therapeutics Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran
  • Publication number: 20090176834
    Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
    Type: Application
    Filed: August 1, 2008
    Publication date: July 9, 2009
    Applicant: Insys Therapeutics Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran, Neha Parikh
  • Publication number: 20080112895
    Abstract: A room temperature stable aqueous cannabinoid formulation is disclosed. In preferred embodiments, the cannabinoid formulation comprises dronabinol in a mixture of buffer solution, and organic cosolvents such as ethanol, propylene glycol and polyethylene glycol.
    Type: Application
    Filed: August 6, 2007
    Publication date: May 15, 2008
    Applicant: Insys Therapeutics Inc.
    Inventors: S. George Kottayil, Venkat R. Goskonda, Zhongyuan Zhu, Linet Kattookaran
  • Publication number: 20040002482
    Abstract: The present invention relates to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a depressive disorder, or the symptoms associated with, or related to a depressive disorder in a subject in need thereof. The present invention also relates to a method of administering a steroid in the testosterone synthetic pathway, for example testosterone, to a subject in need thereof. In addition, the methods, kits, combinations and compositions may be used in conjunction with other pharmaceutical agents including agents effective at treating, preventing, or reducing the risk of developing a depressive disorder in a subject.
    Type: Application
    Filed: March 15, 2002
    Publication date: January 1, 2004
    Inventors: Robert E. Dudley, S. George Kottayil, Olivier Palatchi
  • Publication number: 20030232072
    Abstract: A pharmaceutical composition useful for treating hypogonadism is disclosed. The composition comprises an androgenic or anabolic steroid, a C1-C4 alcohol, a penetration enhancer such as isopropyl myristate, and water. Also disclosed is a method for treating hypogonadism utilizing the composition.
    Type: Application
    Filed: January 3, 2003
    Publication date: December 18, 2003
    Inventors: Robert E. Dudley , S. George Kottayil , Olivier Palatchi
  • Publication number: 20030050292
    Abstract: A pharmaceutical composition useful for treating hypogonadism is disclosed. The composition comprises an androgenic or anabolic steroid, a C1-C4 alcohol, a penetration enhancer such as isopropyl myristate, and water. Also disclosed is a method for treating hypogonadism utilizing the composition.
    Type: Application
    Filed: October 19, 2001
    Publication date: March 13, 2003
    Inventors: Robert E. Dudley, S. George Kottayil, Olivier Palatchi