Patents by Inventor Saburo Hara

Saburo Hara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10527408
    Abstract: There is provided a misalignment detecting device being capable of detecting and correcting distortion of a spoked wheel with a simple configuration.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: January 7, 2020
    Assignee: HOZAN TOOL INDUSTRIAL CO., LTD.
    Inventors: Tomomi Hara, Hiroshi Udagawa, Rikio Kurakane, Saburo Shimokawa, Masahiro Okuno
  • Publication number: 20110185701
    Abstract: A working fluid consisting essentially of CO2, a molecule having a low ratio of specific heats, is expanded by a gas turbine 4. Thus, even if the pressure changes between the inlet side and the outlet side of the gas turbine 4, a temperature drop as a temperature change is suppressed, so that an exhaust gas having a high temperature is obtained. Consequently, the difference between the temperature of the working fluid on the outlet side of a compressor 2 and the temperature of the exhaust gas on the outlet side of the gas turbine 4 is kept so great that a regeneration effect is enhanced, whereby thermal efficiency is increased without a decrease in the output.
    Type: Application
    Filed: September 26, 2008
    Publication date: August 4, 2011
    Applicant: CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUS TRY
    Inventors: Eiichi Koda, Hiromi Shirai, Saburo Hara
  • Publication number: 20080216405
    Abstract: Biomass, including waste biomass, is gasified by a process in which the biomass is first carbonized, and the char and pyrolysis gas from the carbonizer are respectively fed to a high temperature gasifying part and a gas reformer part of a two-stage gasifier A gasifying agent is continuously fed to the gasifying part, and intermittently fed to the gas reformer, to maintain the temperature required to avoid tar formation in the gas reformer stage. Multiple carbonization chambers are operated in rotation. When the carbonization/gasification apparatus is used to provide fuel to an electric power generator set, exhaust heat from the generator power plant is fed back to the carbonizer, and can be supplemented by exchange of heat from the gas delivered to generator power plant from the outlet of the gasifier.
    Type: Application
    Filed: March 3, 2008
    Publication date: September 11, 2008
    Applicants: Central Research Institute of Electric Power Industry, Kanai Office Corporation
    Inventors: Kazuyoshi Ichikawa, Jun Inumaru, Kazuhiro Kidoguchi, Saburo Hara, Masami Ashizawa, Maseo Kanai
  • Publication number: 20050247553
    Abstract: Biomass, including waste biomass, is gasified by a process in which the biomass is first carbonized, and the char and pyrolysis gas from the carbonizer are respectively fed to a high temperature gasifying part and a gas reformer part of a two-stage gasifier. A gasifying agent is continuously fed to the gasifying part, and intermittently fed to the gas reformer, to maintain the temperature required to avoid tar formation in the gas reformer stage. Multiple carbonization chambers are operated in rotation. When the carbonization/gasification apparatus is used to provide fuel to an electric power generator set, exhaust heat from the generator power plant is fed back to the carbonizer, and can be supplemented by exchange of heat from the gas delivered to generator power plant from the outlet of the gasifier.
    Type: Application
    Filed: March 21, 2005
    Publication date: November 10, 2005
    Applicants: Central Research Institute of Electric Power Industry, Kanai Office Corporation
    Inventors: Kazuyoshi Ichikawa, Jun Inumaru, Kazuhiro Kidoguchi, Saburo Hara, Masami Ashizawa, Maseo Kanai
  • Patent number: 6809086
    Abstract: A method of increasing proliferation of cells which comprises adding to cells a cellular proliferating amount of a primary hydroxyl group of N-acetylglucosamine selectively desulfated heparin having the following characteristics for an enzyme digestion product of the heparin: (1) contents of unsaturated disaccharides of the following formulae (a) and (b): measured by high performance liquid chromatography in the enzyme digestion product of the selectively desulfated heparin are less than 40% and 30 to 67%, respectively, (2) a content of disaccharides containing an N-substituted sulfate group is 75 to 95%, and (3) the weight average molecular weight Mw is 4,000 to 30,000 dalton.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: October 26, 2004
    Assignee: Seikagaku Corporation
    Inventors: Saburo Hara, Keiichi Yoshida, Masayuki Ishihara
  • Publication number: 20030149253
    Abstract: This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) 1
    Type: Application
    Filed: December 6, 2002
    Publication date: August 7, 2003
    Applicant: SEIKAGAKU CORPORATION
    Inventors: Saburo Hara, Keiichi Yoshida, Masayuki Ishihara
  • Patent number: 6545136
    Abstract: This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) wherein R1s are the same or different and each represent a hydrogen atom or a halogen atom, R2 represents a lower alkyl group, and R3s are the same or different and each represent a lower alkyl group, an aryl group or a halogen atom, and a desulfated heparin obtained by this production process.
    Type: Grant
    Filed: June 27, 2000
    Date of Patent: April 8, 2003
    Assignee: Seikagaku Corporation
    Inventors: Saburo Hara, Keiichi Yoshida, Masayuki Ishihara
  • Patent number: 6492503
    Abstract: There is provided a glycosaminoglycan having a backbone structure comprising a repetitive disaccharide bearing a uronic acid residue and a glucosamine residue, and having sulfate groups, wherein substantially no sulfate group bound to the hydroxyl group at the 6-position of the glucosamine residue in the backbone structure is detected as determined by a chemical disaccharide analysis method in which the glycosaminoglycan is decomposed with nitrous acid, reacted with para-nitrophenylhydrazine and analyzed by high performance liquid chromatography, and the molar % of a uronic acid residue having a sulfate group at the 2-position is not less than 45% relative to total uronic acid residues, which is calculated from a disaccharide composition obtained by an enzymatic disaccharide analysis method in which the glycosaminoglycan is digested with glycosaminoglycan-degrading enzymes and analyzed by high performance liquid chromatography. The glycosaminoglycan can be used as an active ingredient of pharmaceuticals.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: December 10, 2002
    Assignee: Seikagaku Corporation
    Inventors: Yutaka Kariya, Ryo Takano, Kaeko Kamei, Saburo Hara, Junichi Onaya, Yusuke Hori
  • Patent number: 6191113
    Abstract: A peptide comprising a peptide (A) of an amino acid sequence being abundant in basic amino acid residues and a peptide (B) of an amino acid sequence comprising at least two consecutive, hydrophobic amino acid residues wherein the peptide (B) is linked to the C-terminal of the peptide (A) directly or via several amino acid residues. The novel peptide of the present invention has the activity to inhibit growth of smooth muscle cells and a pharmaceutical composition comprising the peptide is useful for preventing or treating pathological conditions associated with growth of smooth muscle cells such as arteriosclerosis, restenosis after angioplasty, luminal stenosis after grafting blood vessel and smooth muscle sarcoma.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: February 20, 2001
    Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
    Inventors: Yo Nakahara, Saburo Hara, Yuichi Kamikubo, Sumiyo Takemoto, Seiji Miyamoto
  • Patent number: 6140481
    Abstract: This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) ##STR1## wherein R.sup.1 s are the same or different and each represent a hydrogen atom or a halogen atom, R.sup.2 represents a lower alkyl group, and R.sup.3 s are the same or different and each represent a lower alkyl group, an aryl group or a halogen atom,and a desulfated heparin obtained by this production process.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: October 31, 2000
    Assignee: Seikagaku Corporation
    Inventors: Saburo Hara, Keiichi Yoshida, Masayuki Ishihara
  • Patent number: 4735954
    Abstract: Novel anti-rheumatic agent containing 3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine as an active ingredient.
    Type: Grant
    Filed: September 9, 1986
    Date of Patent: April 5, 1988
    Assignee: Kyorin Seiyaku Kabushiki Kaisha
    Inventors: Tsutomu Irikura, Keigo Nishino, Saburo Hara
  • Patent number: 4392906
    Abstract: A plurality of fasteners are joined together as they are laminated in the direction of the thickness thereof, to form a fastener assembly. Each of the fasteners consists of a substantially H-shaped body composed of a head section, a bar section opposed to the head section, and a filament section by which the head section and bar section are joined together. Each of the fasteners is obtained by punching a film or a sheet of a synthetic resin. After a plurality of such fasteners as described above have been laminated in the direction of the thickness thereof, the bar sections are fused together in such a manner that the fasteners can be separated one by one.
    Type: Grant
    Filed: September 9, 1981
    Date of Patent: July 12, 1983
    Assignees: Toska Co., Ltd., Japan Bano'k Co., Ltd., Ben Clements & Sons, Inc.
    Inventor: Saburo Hara