Patents by Inventor Sae-Kwang Ku

Sae-Kwang Ku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11129861
    Abstract: The present invention provides a composition containing, as active ingredients, Panax ginseng, Adenophora triphylla, Wolfiporia extensa, Rehmannia glutinosa, and Mel for an antitussive, expectorant, or anti-inflammatory action, and a composition for preventing, alleviating, or treating a respiratory disease. The present invention provides a compositions having excellent effects compared with an existing antitussive agent and expectorant agent. The compositions of the present invention are a naturally derived material and has little cytotoxicity, and thus is expected to be safely used as a medicine or food composition having antitussive, expectorant, and anti-inflammatory effects.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: September 28, 2021
    Assignee: OKCHUNDANG CO., LTD.
    Inventors: Seong Min Ku, Tae Hun Ku, Chul Jong Jung, Jeong Gyun Seo, Hye Ran Gong, Sae Kwang Ku, Seok Man Park, Ryong Kong, Xian Li, Gyung Yun Beik, Yoeng Eun Yu, Hee Jeong Ryu, Gyu Hyeon Kim
  • Patent number: 11065294
    Abstract: Provided is a composition for enhancing effects of an anticancer agent using an oriental medicine, jaeumganghwa-tang, bojungikgi-tang, or yukmijihwang-tang. More particularly, provided is a composition for treating a neoplastic disease by administering an anticancer agent into an individual, and administering an oriental medicine into the individual within 30 minutes. The composition remarkably reduces side effects occurring when the anticancer agent is administered alone by co-administration of the oriental medicine, reduces cytotoxicity, and has higher anticancer activity than that when the anticancer agent is administered alone.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: July 20, 2021
    Assignee: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Joon Seok Byun, Sae Kwang Ku, Ki Cheul Sohn, Seung Mo Kim, Chang Hyeong Lee, Dae Sung Hyun, Jong Dae Kim, Sung Hwan Park, Min A. Kwak
  • Patent number: 10765647
    Abstract: Provided is a composition for treating diabetes, including a hypoglycemic agent and a Yukmijihwang-tang extract. More particularly, the hypoglycemic agent is administered into an individual, and the Yukmijihwang-tang extract is administered into the individual, thereby considerably increasing a hypoglycemic effect of the hypoglycemic agent, and preventing and reducing various diabetic complications such as diabetes and diabetic liver damage, renal damage, hyperlipidemia immunosuppression and ocular damage.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: September 8, 2020
    Assignee: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Seok Bong Kang, Ho Sang Sohn, Joon Seok Byun, Ki Cheul Sohn, Sae Kwang Ku
  • Patent number: 10695394
    Abstract: The present invention relates to a composition containing a Pinelliae Rhizoma and Scutellariae Radix extract as an active ingredient to reduce side effects caused by an anticancer drug, and more particularly, a composition for reducing side effects such as damage to the gastrointestinal tract and a gastrointestinal motility disorder by administering an anticancer drug. The composition of the present invention has an excellent effect of reducing side effects in administration of the anticancer drug through an antioxidative function, and synthesis, secretion and control of the functions of gastrin and serotonin producing gastrointestinal endocrine cells.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: June 30, 2020
    Assignee: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Heon Mo Ryu, Dae Jun Kim, Joon Seok Byun, Ki Cheul Sohn, Sae Kwang Ku
  • Publication number: 20190358283
    Abstract: The present invention provides a pharmaceutical composition for preventing or treating cancer, a food composition for enhancing immune functions, and a pharmaceutical composition for preventing or treating cachexia. The composition of the present invention provides effects of further inhibiting the growth of tumors, increasing immunological activity, and suppressing cachexia caused by tumors. In addition, the composition of the present invention can obtain a synergistic effect when co-administered with an existing anticancer drug.
    Type: Application
    Filed: January 16, 2019
    Publication date: November 28, 2019
    Inventors: Sae Kwang KU, Seong Min KU, Tae Hun KU, Chul Jong JUNG, Gyung Yun BEIK, Jin Gi SHIN, Sang Soo LEE, Jeong Gyun SEO, Chil Surk YOON, Xian LI
  • Patent number: 10342835
    Abstract: The present invention relates to a composition for promoting proliferation of bone marrow derived stem cells using an angelicae gigantis radix extract, and more particularly, to a composition which administers a granulocyte colony-stimulating factor into an object, and administers the angelicae gigantis radix extract to the object to promote the proliferation of the bone marrow derived stem cells. The composition of the present invention solves side effects such as splenomegaly which were caused by a method of administering only the G-CSF for proliferation and differentiation of the stem cells, thereby significantly mitigating the side effects through co-administration of the angelicae gigantis radix extract, and further promoting the proliferation and the differentiation of the stem cells.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: July 9, 2019
    Assignee: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Chang Hyeong Lee, Sang Gyung Kim, Im Hee Shin, Seung Mo Kim, Joon Seok Byun, Ki Cheul Sohn, Sae Kwang Ku
  • Patent number: 10286040
    Abstract: The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmultang extract, and more specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering the palmultang extract to the subject. The composition of the present invention remarkably reduces side effects, such as enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, through administration in combination with the palmultang extract, thereby further promoting the proliferation and differentiation of stem cells.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: May 14, 2019
    Assignee: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Chang Hyeong Lee, Sang Gyung Kim, Im Hee Shin, Seung Mo Kim, Joon Seok Byun, Ki Cheul Sohn, Sae Kwang Ku
  • Patent number: 10265333
    Abstract: The present invention relates to a lipid nanomaterial containing lysophosphatidylcholine or an ether derivative thereof, a method for preparing the same, a method for reducing erythrocyteolysis and hemagglutination using the compound, and a pharmaceutical agent containing the lipid nanomaterial. The present invention contains lysophosphatidylcholine or an ether derivative thereof as an active ingredient, and can be useful as a treatment agent for septicemia, bacterial infection diseases, and the like.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: April 23, 2019
    Assignee: ARIBIO CO., LTD.
    Inventors: Jai Jun Choung, Myung Hwa Kim, Du Jin Seol, Sae Kwang Ku, Soo Hyun Sung, Young Sam Kim
  • Publication number: 20190060384
    Abstract: The present invention relates to a composition for the treatment or prevention of lung cancer, including gefitinib and a Lonicera japonica extract, and more particularly, the present invention has an advantage in that it is possible to remarkably increase the therapeutic effects of gefitinib on lung cancer and simultaneously prevent and reduce side effects caused by various treatments of lung cancer, and the like by administering gefitinib to an individual and administering a Lonicera japonica extract to the individual.
    Type: Application
    Filed: August 20, 2018
    Publication date: February 28, 2019
    Applicant: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Sang Hoon Joo, Young Joon Lee, Sae-Kwang Ku, Joon-Seok Byun, Ki Cheul Sohn
  • Publication number: 20190046477
    Abstract: Provided is a composition for treating diabetes, including a hypoglycemic agent and a Yukmijihwang-tang extract. More particularly, the hypoglycemic agent is administered into an individual, and the Yukmijihwang-tang extract is administered into the individual, thereby considerably increasing a hypoglycemic effect of the hypoglycemic agent, and preventing and reducing various diabetic complications such as diabetes and diabetic liver damage, renal damage, hyperlipidemia immunosuppression and ocular damage.
    Type: Application
    Filed: May 3, 2018
    Publication date: February 14, 2019
    Applicant: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Seok Bong Kang, Ho Sang Sohn, Joon Seok Byun, Ki Cheul Sohn, Sae Kwang Ku
  • Publication number: 20180289763
    Abstract: The present invention relates to a composition containing a Pinelliae Rhizoma and Scutellariae Radix extract as an active ingredient to reduce side effects caused by an anticancer drug, and more particularly, a composition for reducing side effects such as damage to the gastrointestinal tract and a gastrointestinal motility disorder by administering an anticancer drug. The composition of the present invention has an excellent effect of reducing side effects in administration of the anticancer drug through an antioxidative function, and synthesis, secretion and control of the functions of gastrin and serotonin producing gastrointestinal endocrine cells.
    Type: Application
    Filed: April 26, 2018
    Publication date: October 11, 2018
    Applicant: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Heon Mo RYU, Dae Jun KIM, Joon Seok BYUN, Ki Cheul SOHN, Sae Kwang KU
  • Patent number: 10064865
    Abstract: The present invention relates to a composition and health functional food for inhibiting apoptosis of cranial nerve cells, and to a method for inhibiting apoptosis, wherein the composition and health functional food comprising a phosphodiesterase type 5 active inhibitor. According to the present invention, the PDE5 inhibitor exhibits a protective effect on nerve cells by inhibiting apoptosis of cranial nerve cells. Thus, the present invention can be effectively used to prevent, alleviate, and treat cranial nerve disease.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: September 4, 2018
    Assignees: ARIBIO CO., LTD., SK CHEMICALS CO., LTD.
    Inventors: Myung Hwa Kim, Jae Jun Choung, Sae Kwang Ku
  • Publication number: 20180243358
    Abstract: The present invention relates to a composition for promoting proliferation of bone marrow derived stem cells using an angelicae gigantis radix extract, and more particularly, to a composition which administers a granulocyte colony-stimulating factor into an object, and administers the angelicae gigantis radix extract to the object to promote the proliferation of the bone marrow derived stem cells. The composition of the present invention solves side effects such as splenomegaly which were caused by a method of administering only the G-CSF for proliferation and differentiation of the stem cells, thereby significantly mitigating the side effects through co-administration of the angelicae gigantis radix extract, and further promoting the proliferation and the differentiation of the stem cells.
    Type: Application
    Filed: May 2, 2018
    Publication date: August 30, 2018
    Applicant: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Chang Hyeong LEE, Sang Gyung KIM, Im Hee SHIN, Seung Mo KIM, Joon Seok BYUN, Ki Cheul SOHN, Sae Kwang KU
  • Publication number: 20180214499
    Abstract: The present invention provides a composition containing, as active ingredients, Panax ginseng, Adenophora triphylla, Wolfiporia extensa, Rehmannia glutinosa, and Mel for an antitussive, expectorant, or anti-inflammatory action, and a composition for preventing, alleviating, or treating a respiratory disease. The present invention provides a compositions having excellent effects compared with an existing antitussive agent and expectorant agent. The compositions of the present invention are a naturally derived material and has little cytotoxicity, and thus is expected to be safely used as a medicine or food composition having antitussive, expectorant, and anti-inflammatory effects.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 2, 2018
    Inventors: Seong Min KU, Tae Hun KU, Chul Jong JUNG, Yun Young CHO, Jeong Gyun SEO, Nam Oh KIM, Hee Yoon JEONG, Eun Sik CHOI, Hye Ran GONG, Sae Kwang KU
  • Publication number: 20180185447
    Abstract: The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmultang extract, and specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering the palmultang extract to the subject. The composition of the present invention remarkably reduces side effects, such as enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, through administration in combination with the palmultang extract, thereby further promoting the proliferation and differentiation of stem cells.
    Type: Application
    Filed: December 26, 2017
    Publication date: July 5, 2018
    Applicant: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
    Inventors: Chang Hyeong LEE, Sang Gyung KIM, Im Hee SHIN, Seung Mo KIM, Joon Seok BYUN, Ki Cheul SOHN, Sae Kwang KU
  • Publication number: 20170326145
    Abstract: The present invention relates to a composition and health functional food for inhibiting apoptosis of cranial nerve cells, and to a method for inhibiting apoptosis, wherein the composition and health functional food comprising a phosphodiesterase type 5 active inhibitor. According to the present invention, the PDE5 inhibitor exhibits a protective effect on nerve cells by inhibiting apoptosis of cranial nerve cells. Thus, the present invention can be effectively used to prevent, alleviate, and treat cranial nerve disease.
    Type: Application
    Filed: July 28, 2017
    Publication date: November 16, 2017
    Applicants: ARIBIO INC., SK CHEMICALS CO., LTD.
    Inventors: Myung Hwa KIM, Jae Jun CHOUNG, Sae Kwang KU
  • Patent number: 9750743
    Abstract: The present invention relates to a composition and health functional food for inhibiting apoptosis of cranial nerve cells, and to a method for inhibiting apoptosis, wherein the composition and health functional food comprising a phosphodiesterase type 5 active inhibitor. According to the present invention, the PDE5 inhibitor exhibits a protective effect on nerve cells by inhibiting apoptosis of cranial nerve cells. Thus, the present invention can be effectively used to prevent, alleviate, and treat cranial nerve disease.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: September 5, 2017
    Assignees: ARIBIO INC., SK CHEMICALS CO., LTD.
    Inventors: Myung Hwa Kim, Jae Jun Choung, Sae Kwang Ku
  • Publication number: 20170165295
    Abstract: The present invention relates to a functional composition for preventing, alleviating or treating constipation, containing high hardness mineral water prepared from deep ocean water or desalinated groundwater, and a method therefor. The present invention contains high hardness mineral water prepared from deep ocean water or desalinated groundwater as an active ingredient so as to be safe to the human body, and thus can be useful for treating constipation of a cancer patient and constipation of a regular person.
    Type: Application
    Filed: January 5, 2017
    Publication date: June 15, 2017
    Inventors: Jai Jun CHOUNG, Soo Hyun SUNG, Sae Kwang KU
  • Publication number: 20170042198
    Abstract: The present invention relates to a functional beverage including high hardness mineral water produced from salty underground water or deep seawater as an effective ingredient. The functional beverage of the present invention may not only impart a refreshing sensation in the mouth upon consumption, but may also effectively remove fatigue-causing substances such as lactic acid and free oxygen radicals and increase ATP production in the body, and vitalize one's lifestyle and improve exercise capacity and cognitive functions. The functional beverage of the present invention may show the effects of improving or maintaining anti-inflammatory and immune functions.
    Type: Application
    Filed: March 31, 2015
    Publication date: February 16, 2017
    Inventors: Jai Jun CHOUNG, Soo Hyun SUNG, Sae Kwang KU, Young Joon LEE, Jong Kyu KIM, Chang Ho SHIN
  • Patent number: 9446061
    Abstract: The present invention relates to: a pharmaceutical composition containing lysophosphatidylcholine or analogs thereof and antibiotics as active ingredients for boosting immunity or the treatment of bacterial infections; a method for boosting immunity or the treatment of bacterial infections, which comprises a step for administering the composition; and a kit containing the composition for boosting immunity or the treatment of bacterial infections.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: September 20, 2016
    Assignee: ARIMED INC.
    Inventors: Jai Jun Choung, Sae Kwang Ku, Dong Keun Song