Patents by Inventor Safiyh Taghavi
Safiyh Taghavi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240096440Abstract: Methods are provided for the rational design of stable communities of microbes for benefiting the health of a host organism, including human and/or animal health. The methods describe design of microbial consortia based on providing and/or complementing key functionalities lacking or underrepresented in the microbiome of an organism having a disorder or disease as compared to healthy subjects. The consortia are designed to possess metabolic interdependencies for improved engrafting, stability and performance of the consortium. Compositions that include the designed microbial consortia are provided for treatment of disorders/diseases involving chronic inflammation, infection, and the combination of chronic inflammation and infection including inflammatory bowel disease and related disorders. The compositions are also broadly applicable for the treatment of neurological, metabolic and oncology-related conditions.Type: ApplicationFiled: September 13, 2023Publication date: March 21, 2024Inventors: Daniel van der Lelie, Safiyh Taghavi
-
Publication number: 20230381247Abstract: Compositions containing live cultures of 11 separately isolated bacterial strains (the bacterial consortium containing all 11 strains designated GUT-108) are provided for treating conditions of systemic inflammation including, to name a few, Inflammatory Bowel Diseases, type-2 diabetes, metabolic syndrome and obesity, and aging-related conditions of chronic inflammation. In a mouse model of chronic immune-mediated colitis, therapeutic application of GUT-108 reversed the established inflammation in the cecum. In addition, the treatment with GUT-108 unexpectedly resulted in restoration of a healthy gut microbiome in the mice containing an abundance of beneficial Clostridium strains not part of GUT-108, and a decrease in abundance of the applied pathogenic Enterobacteriaceae bacteria from 5% to below 0.5%.Type: ApplicationFiled: October 14, 2021Publication date: November 30, 2023Inventors: Daniel van der Lelie, Safiyh Taghavi
-
Patent number: 11810650Abstract: Methods are provided for the rational design of stable communities of microbes for benefiting the health of a host organism, including human and/or animal health. The methods describe design of microbial consortia based on providing and/or complementing key functionalities lacking or underrepresented in the microbiome of an organism having a disorder or disease as compared to healthy subjects. The consortia are designed to possess metabolic interdependencies for improved engrafting, stability and performance of the consortium. Compositions that include the designed microbial consortia are provided for treatment of disorders/diseases involving chronic inflammation, infection, and the combination of chronic inflammation and infection including inflammatory bowel disease and related disorders. The compositions are also broadly applicable for the treatment of neurological, metabolic and oncology-related conditions.Type: GrantFiled: October 3, 2019Date of Patent: November 7, 2023Assignee: Gusto Global, LLCInventors: Daniel van der Lelie, Safiyh Taghavi
-
Publication number: 20230077291Abstract: The present application discloses method of controlling plant pathogen(s), e.g. fungal and bacterial pathogens, on a plant, wherein a composition comprising Bacillus amyloliquefaciens FCC1256 deposited as ATCC No. PTA-122162 is applied to the plant, in particular to over-ground parts of the plant. The composition may comprise iturin and fengycin in a relative weight ratio of 1.3:1.0 to 3.0:1.0. The application also discloses an agricultural composition comprising the novel strain, a carrier, a surface-active agent and optionally a buffer, and a corresponding concentrate.Type: ApplicationFiled: November 16, 2022Publication date: March 9, 2023Applicant: FMC CorporationInventors: Daniel Van Der Lelie, Safiyh Taghavi, Anthony Andrew Devine, Jaeheon Lee
-
Patent number: 11528910Abstract: Methods of controlling a plant pathogen, e.g. fungal and bacterial pathogens, on a plant, are described wherein an agricultural composition comprising Bacillus amyloliquefaciens FCC1256 deposited as ATCC No. PTA-122162, a carrier, a surface-active agent and optionally a buffer, and a corresponding concentrate is also described.Type: GrantFiled: September 27, 2019Date of Patent: December 20, 2022Assignee: FMC CorporationInventors: Daniel Van Der Lelie, Safiyh Taghavi, Anthony Andrew Devine, Jaeheon Lee
-
Patent number: 10645934Abstract: The present invention relates to a novel species of Enterobacter, Enterobacter sp. 638, and to its use in connection, for example, with a method for increasing growth in a plant, increasing biomass in a plant, increasing fruit and/or seed productivity in a plant, increasing disease tolerance and/or resistance in a plant, and increasing drought tolerance and/or resistance in a plant, as compared to a control or wild-type plant grown under identical conditions without application of the inventive method or composition. The methods include applying an effective amount of a composition, which includes an isolated culture of Enterobacter sp. 638, to the plant.Type: GrantFiled: March 10, 2011Date of Patent: May 12, 2020Assignee: BROOKHAVEN SCIENCE ASSOCIATES/BROOKHAVEN NATIONAL LABORATORYInventors: Lee Newman, Daniel van der Lelie, Safiyh Taghavi
-
Publication number: 20200100504Abstract: The present application discloses method of controlling plant pathogen(s), e.g. fungal and bacterial pathogens, on a plant, wherein a composition comprising Bacillus amyloliquefaciens FCC1256 deposited as ATCC No. PTA-122162 is applied to the plant, in particular to over-ground parts of the plant. The composition may comprise iturin and fengycin in a relative weight ratio of 1.3:1.0 to 3.0:1.0. The application also discloses an agricultural composition comprising the novel strain, a carrier, a surface-active agent and optionally a buffer, and a corresponding concentrate.Type: ApplicationFiled: September 27, 2019Publication date: April 2, 2020Inventors: Daniel Van Der Lelie, Safiyh Taghavi, Anthony Andrew Devine, Jaeheon Lee
-
Publication number: 20200027524Abstract: Methods are provided for the rational design of stable communities of microbes for benefiting the health of a host organism, including human and/or animal health. The methods describe design of microbial consortia based on providing and/or complementing key functionalities lacking or underrepresented in the microbiome of an organism having a disorder or disease as compared to healthy subjects. The consortia are designed to possess metabolic interdependencies for improved engrafting, stability and performance of the consortium. Compositions that include the designed microbial consortia are provided for treatment of disorders/diseases involving chronic inflammation, infection, and the combination of chronic inflammation and infection including inflammatory bowel disease and related disorders. The compositions are also broadly applicable for the treatment of neurological, metabolic and oncology-related conditions.Type: ApplicationFiled: October 3, 2019Publication date: January 23, 2020Inventors: Daniel van der Lelie, Safiyh Taghavi
-
Publication number: 20200016256Abstract: Provided herein are compositions (e.g., probiotic, pharmaceutical, etc.) comprising one or more strains of non-Clostridia class bacteria and methods of use thereof for allergen desensitization. In particular, bacteria of bacterial classes such as Negativicutes, Actinobacteria, and Bacteroidia support allergen desensitization, for example, by promoting production of metabolites that aid in desensitization or performing catabolism of food allergens.Type: ApplicationFiled: September 22, 2017Publication date: January 16, 2020Applicants: The University of Chicago, Gusto Global, LLCInventors: Jack A. GILBERT, Daniel van der LELIE, Safiyh TAGHAVI
-
Patent number: 10390535Abstract: Compositions are provided that include a new Bacillus thuringiensis strain designated RTI545 for use in benefiting plant growth and controlling plant pests. In particular, the RTI545 strain is useful for controlling plant nematode, insect and fungal pests. The compositions include plant seeds coated with the RTI545 strain. The compositions can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, or fertilizers. In one example, enhanced growth and insect control are provided by delivering at the time of planting a combination of a chemical insecticide such as bifenthrin and a liquid fertilizer to plants or seeds treated with RTI545.Type: GrantFiled: October 5, 2017Date of Patent: August 27, 2019Assignee: FMC CorporationInventors: Daniel Van Der Lelie, Safiyh Taghavi, Vincent J. Spadafora, Sylwia L. Fudali-Alves, Nathan Caldwell, Matthew F. Pye, Anders Obel, Robert B. Albright, Guozhi Wang, Chelsea E. Tirrell, Gorm V. Petersen, Jaeheon Lee, Anthony Devine, Roderick G. McLeod, Kevin Brost, John E. Kibbee
-
Patent number: 10375964Abstract: Compositions and methods are provided for a combination of a new strain of Bacillus amyloliquefaciens RTI301 and a new strain of Bacillus subtilis RTI477, the combination having growth promoting activity and activity against plant pathogens. The compositions containing the RTI301 and RTI477 strains are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant roots, seeds, callus tissue, grafts, and cuttings. Synergistic results are observed for the combination of the strains, and the combination of strains is useful to increase yield in crops including soybean and corn. The compositions containing the combination of strains can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.Type: GrantFiled: December 28, 2015Date of Patent: August 13, 2019Assignee: FMC CorporationInventors: Safiyh Taghavi, Daniel van der Lelie, Roderick McLeod, Kevin R. Brost, John E. Kibbee
-
Publication number: 20190216091Abstract: Compositions and methods for application to plants are provided for a new strain of Bacillus licheniformis RTI184 having plant growth promoting activity. Compositions and extracts of Bacillus licheniformis strains that include newly identified Fengycin-like and Dehydroxyfengycin-like cyclic lipopeptides designated as “Fengycin MB-Cit” and “Dehydroxyfengycin MB-Cit”, respectively, are also provided. In particular aspects, compositions containing the Bacillus licheniformis strain RTI184 can be applied alone or in combination with chemical agents or other microbial agents to benefit plant growth.Type: ApplicationFiled: March 27, 2019Publication date: July 18, 2019Inventors: Safiyh Taghavi, Daniel Van Der Lelie, Jaeheon Lee
-
Publication number: 20190191707Abstract: Compositions and methods include a combination of a strain of Bacillus licheniformis CH200 and a strain of Bacillus subtilis CH201 for delivery to plants and plant seeds, the combination having activity against plant fungal pathogens. In particular, the combination of strains is useful for increasing yield in crops including soybean and corn in the presence of plant pathogens. The Bacillus licheniformis CH200 and Bacillus subtilis CH201 strains can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.Type: ApplicationFiled: August 30, 2017Publication date: June 27, 2019Inventors: Safiyh Taghavi, Daniel Van Der Lelie, Jaeheon Lee, Roderick Mcleod, John E. Kibbee, Kevin R. Brost, Guozhi Wang, Vincent J. Spadafora, Matthew F. Pye
-
Publication number: 20180195138Abstract: Compositions and methods include a new strain of Bacillus amyloliquefaciens having growth promoting activity and activity against plant pathogens. The compositions are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant foliage, flowers, fruits, bark, roots, seeds, callus tissue, grafts, cuttings, surrounding soil or growth medium, and soil or growth medium concomitant with sowing seed and planting callus tissue, grafts, and cuttings. The compositions containing the Bacillus amyloliquefaciens RTI301 strain can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.Type: ApplicationFiled: January 8, 2018Publication date: July 12, 2018Inventors: Safiyh Taghavi, Daniel Van Der Lelie, Jaeheon Lee
-
Publication number: 20180092363Abstract: Compositions are provided that include a new Bacillus thuringiensis strain designated RTI545 for use in benefiting plant growth and controlling plant pests. In particular, the RTI545 strain is useful for controlling plant nematode, insect and fungal pests. The compositions include plant seeds coated with the RTI545 strain. The compositions can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, or fertilizers. In one example, enhanced growth and insect control are provided by delivering at the time of planting a combination of a chemical insecticide such as bifenthrin and a liquid fertilizer to plants or seeds treated with RTI545.Type: ApplicationFiled: October 5, 2017Publication date: April 5, 2018Inventors: Daniel Van Der Lelie, Safiyh Taghavi, Vincent J. Spadafora, Sylwia L. Fudali-Alves, Nathan Caldwell, Matthew F. Pye, Anders Obel, Robert B. Albright, Guozhi Wang, Chelsea E. Tirrell, Gorm V. Petersen, Jaeheon Lee, Anthony Devine, Roderick G. McLeod
-
Publication number: 20180020676Abstract: Compositions and methods include a new strain of Bacillus velezensis having growth promoting activity and activity against plant pathogens. The compositions are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant foliage, flowers, fruits, bark, roots, seeds, callus tissue, grafts, cuttings, surrounding soil or growth medium, and soil or growth medium concomitant with sowing seed and planting callus tissue, grafts, and cuttings. The compositions containing the Bacillus velezensis RTI301 strain can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.Type: ApplicationFiled: October 6, 2017Publication date: January 25, 2018Inventors: Safiyh Taghavi, Daniel Van Der Lelie, Jaeheon Lee, Anthony Devine
-
Publication number: 20170367347Abstract: Compositions and methods are provided for a combination of a new strain of Bacillus amyloliquefaciens RTI301 and a new strain of Bacillus subtilis RTI477, the combination having growth promoting activity and activity against plant pathogens. The compositions containing the RTI301 and RTI477 strains are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant roots, seeds, callus tissue, grafts, and cuttings. Synergistic results are observed for the combination of the strains, and the combination of strains is useful to increase yield in crops including soybean and corn. The compositions containing the combination of strains can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.Type: ApplicationFiled: December 28, 2015Publication date: December 28, 2017Inventors: Safiyh Taghavi, Daniel van der Lelie, Roderick McLeod, Kevin R. Brost, John E. Kibbee
-
Publication number: 20170196226Abstract: Compositions and methods include a new strain of Bacillus amyloliquefaciens having activity against plant pathogens. The compositions are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant foliage, flowers, fruits, bark, roots, seeds, callus tissue, grafts, cuttings, surrounding soil or growth medium, and soil or growth medium concomitant with sowing seed and planting callus tissue, grafts, and cuttings. The compositions containing the Bacillus amyloliquefaciens RTI472 strain can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, or fertilizers.Type: ApplicationFiled: March 17, 2017Publication date: July 13, 2017Inventors: Safiyh Taghavi, Daniel Van Der Lelie, Melanie Ann R. Silinski, Jaeheon Lee
-
Patent number: 9622484Abstract: Compositions and methods are provided for a combination of a new strain of Bacillus amyloliquefaciens RTI301 and a new strain of Bacillus subtilis RTI477, the combination having growth promoting activity and activity against plant pathogens. The compositions containing the RTI301 and RTI477 strains are useful for benefiting plant growth and/or conferring protection against a pathogenic infection when applied to plant roots, seeds, callus tissue, grafts, and cuttings. Synergistic results are observed for the combination of the strains, and the combination of strains is useful to increase yield in crops including soybean and corn. The compositions containing the combination of strains can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, and fertilizers.Type: GrantFiled: December 28, 2015Date of Patent: April 18, 2017Assignee: FMC CorporationInventors: Safiyh Taghavi, Daniel van der Lelie, Roderick McLeod, Kevin R. Brost, John E. Kibbee
-
Patent number: RE49311Abstract: Compositions are provided that include a new Bacillus thuringiensis strain designated RTI545 for use in benefiting plant growth and controlling plant pests. In particular, the RTI545 strain is useful for controlling plant nematode, insect and fungal pests. The compositions include plant seeds coated with the RTI545 strain. The compositions can be applied alone or in combination with other microbial, biological, or chemical insecticides, fungicides, nematicides, bacteriocides, herbicides, plant extracts, plant growth regulators, or fertilizers. In one example, enhanced growth and insect control are provided by delivering at the time of planting a combination of a chemical insecticide such as bifenthrin and a liquid fertilizer to plants or seeds treated with RTI545.Type: GrantFiled: January 22, 2020Date of Patent: November 29, 2022Assignee: FMC CorporationInventors: Daniel Van Der Lelie, Safiyh Taghavi, Vincent J. Spadafora, Nathan Caldwell, Anders Obel, Robert B. Albright, Guozhi Wang, Jaeheon Lee, Roderick G. McLeod, Kevin Brost, John E. Kibbee