Patents by Inventor Sagar Ramdas Amale

Sagar Ramdas Amale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10822336
    Abstract: Provided are novel crystals of [2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and a pharmaceutically acceptable salt thereof having advantageous characteristics. [2-(1-Methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and a pharmaceutically acceptable salt thereof provided by the present invention are excellent in stability and have satisfactory physical properties as a drug substance of a pharmaceutical product.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: November 3, 2020
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Yasushi Ueda, Sagar Ramdas Amale, Manjunath Govind Bhovi
  • Publication number: 20190225614
    Abstract: Provided are novel crystals of [2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and a pharmaceutically acceptable salt thereof having advantageous characteristics. [2-(1-Methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and a pharmaceutically acceptable salt thereof provided by the present invention are excellent in stability and have satisfactory physical properties as a drug substance of a pharmaceutical product.
    Type: Application
    Filed: September 28, 2017
    Publication date: July 25, 2019
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Yasushi Ueda, Sagar Ramdas Amale, Manjunath Govind Bhovi
  • Patent number: 10174035
    Abstract: The present invention relates to a pyrazole derivative of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, stereoisomer thereof or a deuterium form thereof, wherein, n, Y, Ra, R1, R2, R3, R4, R5 and R6 are as defined hereinafter in the specification, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) as inhibitors of phosphatidylinositol-3-kinase (PI3K), which can be used for treating or preventing inflammatory, autoimmune, orphan and hyperproliferative disease and disorder.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: January 8, 2019
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Kirandeep Kaur Samby, Yogesh Baban Surase, Sagar Ramdas Amale, Suresh Kumar Gorla, Priyanka Patel, Ashwani Kumar Verma
  • Publication number: 20180072732
    Abstract: The present invention relates to a pyrazole derivative of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, stereoisomer thereof or a deuterium form thereof, wherein, n, Y, Ra, R1, R2, R3, R4, R5 and R6 are as defined hereinafter in the specification, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) as inhibitors of phosphatidylinositol-3-kinase (PI3K), which can be used for treating or preventing inflammatory, autoimmune, orphan and hyperproliferative disease and disorder.
    Type: Application
    Filed: March 29, 2016
    Publication date: March 15, 2018
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Kirandeep Kaur Samby, Yogesh Baban Surase, Sagar Ramdas Amale, Suresh Kumar Gorla, Priyanka Patel, Ashwani Kumar Verma