Patents by Inventor Sami ELLOUZE

Sami ELLOUZE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE CELL ANALYSIS
    Publication number: 20230063190
    Abstract: The present invention concerns processes for barcoding nucleic acids from single cells and processes for genotyping ingle cells having a phenotype of interest.
    Type: Application
    Filed: August 26, 2022
    Publication date: March 2, 2023
    Inventors: Marcel Reichen, Arnaud Reitz, Bingqing Shen, Sami Ellouze, Annabelle Gérard
  • Method for analyzing and selecting a specific droplet among a plurality of droplets and associated apparatus
    Patent number: 11592367
    Abstract: The present invention relates to a method for analyzing and selecting a specific droplet among a plurality of droplets (4), comprising the following steps: —providing a plurality of droplets (4), —for a droplet (4) among the plurality of droplets, measuring at least two optical signals, each optical signal being representative of a light intensity spatial distribution in the droplet for an associated wavelength channel, —calculating a plurality of parameters from the optical signals, —determining a sorting class for a droplet according to calculated parameters, —sorting said droplet according to its sorting class, wherein the plurality of parameters comprises the coordinates of a maximum for each optical signal and a co-localization parameter and the at least two calculated parameters used for the determining step comprises the co-localization parameter.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: February 28, 2023
    Assignee: HIFIBIO SAS
    Inventors: Marcel Reichen, Raphael Clément Li-Ming Doineau, Sami Ellouze
  • Single cell analysis
    Patent number: 11427853
    Abstract: The present invention concerns processes for barcoding nucleic acids from single cells and processes for genotyping single cells having a phenotype of interest.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: August 30, 2022
    Assignee: HIFIBIO SAS
    Inventors: Marcel Reichen, Arnaud Reitz, Bingqing Shen, Sami Ellouze, Annabelle Gerard
  • PROCESS FOR MANUFACTURING AN ARRAY WITH MICROCHANNELS
    Publication number: 20210154674
    Abstract: The invention relates to a process for manufacturing a microfluidic chip comprising a solid material obtained from a sol-gel solution, the process comprising successively: a) casting a sol-gel solution made with tetraethyl orthosilicate onto a mold presenting a relief pattern and having a different thickness over the whole of the mold; b) gelling the sol-gel solution; c) unmolding and drying the gel obtained in b), so as to obtain a solid glass; and d) bonding said solid glass to a support, so as to obtain the microfluidic chip.
    Type: Application
    Filed: May 18, 2018
    Publication date: May 27, 2021
    Inventors: Arnaud Reitz, Marcel Reichen, Bingqing Shen, Sami Ellouze
  • SINGLE CELL ANALYSIS
    Publication number: 20200199649
    Abstract: The present invention concerns processes for barcoding nucleic acids from single cells and processes for genotyping single cells having a phenotype of interest.
    Type: Application
    Filed: March 15, 2018
    Publication date: June 25, 2020
    Inventors: Marcel Reichen, Arnaud Reitz, Bingqing Shen, Sami Ellouze, Annabelle Gerard
  • METHOD FOR ANALYZING AND SELECTING A SPECIFIC DROPLET AMONG A PLURALITY OF DROPLETS AND ASSOCIATED APPARATUS
    Publication number: 20190376879
    Abstract: The present invention relates to a method for analyzing and selecting a specific droplet among a plurality of droplets (4), comprising the following steps: —providing a plurality of droplets (4), —for a droplet (4) among the plurality of droplets, measuring at least two optical signals, each optical signal being representative of a light intensity spatial distribution in the droplet for an associated wavelength channel, —calculating a plurality of parameters from the optical signals, —determining a sorting class for a droplet according to calculated parameters, —sorting said droplet according to its sorting class, wherein the plurality of parameters comprises the coordinates of a maximum for each optical signal and a co-localization parameter and the at least two calculated parameters used for the determining step comprises the co-localization parameter.
    Type: Application
    Filed: January 18, 2018
    Publication date: December 12, 2019
    Inventors: Marcel Reichen, Raphael Clément Li-Ming Doineau, Sami Ellouze
  • METHOD FOR TRANSCRIPTOME ANALYSIS OF SINGLE CELLS
    Publication number: 20190345537
    Abstract: The present invention concerns a method for capturing and barcoding nucleic acid from single cells, a plurality of microfluidic droplets and a method for preparing said plurality of microfluidic droplets.
    Type: Application
    Filed: December 8, 2016
    Publication date: November 14, 2019
    Inventors: Annabelle Patricia Véronique GERARD, Kévin Armand SELIN, Adeline Frédérique, Joëlle POITOU, Sami ELLOUZE, Yannick Michel, Louis POUSSE, Marcel REICHEN, Allan JENSEN, Colin Brenan