Patents by Inventor Samie Jaffrey

Samie Jaffrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9861651
    Abstract: The invention provides a method of preventing or treating hearing loss in a mammal in need thereof. The method involves administering to the mammal an agent that increases intracellular NAD+ in the mammal. The invention also provides a method of determining if a compound acts as a neuroprotective agent.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: January 9, 2018
    Assignee: CORNELL UNIVERSITY
    Inventors: Kevin Brown, Anthony Sauve, Samie Jaffrey
  • Publication number: 20150174148
    Abstract: The invention provides a method of preventing or treating hearing loss in a mammal in need thereof. The method involves administering to the mammal an agent that increases intracellular NAD+ in the mammal. The invention also provides a method of determining if a compound acts as a neuroprotective agent.
    Type: Application
    Filed: July 15, 2013
    Publication date: June 25, 2015
    Inventors: Kevin Brown, Anthony Sauve, Samie Jaffrey
  • Publication number: 20050277131
    Abstract: The invention provides a method to C-terminally label proteins in a complex sample and identify those proteins, e.g., using mass spectrometry.
    Type: Application
    Filed: February 11, 2005
    Publication date: December 15, 2005
    Inventor: Samie Jaffrey
  • Publication number: 20050026227
    Abstract: Many of the effects of nitric oxide are mediated by the direct modification of cysteine residues resulting in an adduct called a nitrosothiol. A method to detect proteins which contain nitrosothiols involves several steps. Nitrosylated cysteines are converted to tagged cysteines. Tagged proteins can then be detected, for example, by immunoblotting and/or can be purified by affinity chromatography. The method is applicable to the detection of S-nitrosylated proteins in cell lysates following in vitro S-nitrosylation, as well as to the detection of endogenous S-nitrosothiols in selected protein substrates.
    Type: Application
    Filed: August 27, 2004
    Publication date: February 3, 2005
    Applicants: The Johns Hopkins University, Memorial Sloan-Kettering Cancer Center
    Inventors: Solomon Snyder, Samie Jaffrey, Christopher Ferris, Hediye Erdjument-Bromage, Paul Tempst