Patents by Inventor Samson AFEWERKI

Samson AFEWERKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230354807
    Abstract: The invention relates to the film-forming antimicrobial, antibacterial, antiviral, antiparasitic, and antifungal composition comprises a) a film-forming materials, b) one or more antimicrobial, antibacterial, antiviral, antiparasitic, and antifungal compound(s), c) one or more solubilizing agents, and optionally, d) one or more plasticizer, and e), one or more surfactants or detergents. The invention also relates to a use in prevention or treatment of a disorder in a mammal, such as a human and use of treating animated and non-animated surfaces.
    Type: Application
    Filed: September 22, 2021
    Publication date: November 9, 2023
    Applicant: VERI NANO INC.
    Inventors: Samson AFEWERKI, Guillermo U. RUIZ ESPARZA HERRERA, Joseph V. Bonventre, Nathan N. Lee, Ketian ZHANG
  • Publication number: 20230021329
    Abstract: The present invention relates to a composition comprising a plurality of silicate nanoparticles; a hydrophilic polymer; and water, and optionally further comprising a thickening polymer; a plurality of zinc oxide particles; a polymer comprising a plurality of quaternary ammonium functional groups; an adhesive polymer; an oil or a polyol. The invention also relates to a use of the composition in prevention and/or treatment of a disease in a mammal, such as skin disease or mastitis. The invention relates further to a sealant of a duct in a body of a mammal comprising said composition.
    Type: Application
    Filed: December 18, 2020
    Publication date: January 26, 2023
    Applicant: Veri Nano Inc.
    Inventors: Guillermo U. RUIZ ESPARZA HERRERA, Kanny CHANG, Ketian ZHANG, Samson AFEWERKI
  • Publication number: 20230017661
    Abstract: The present invention relates to a cyclic polysaccharide compound and particle comprising a plurality of said cyclic polysaccharide compounds and one or more agent, wherein the plurality of cyclic polysaccharide compounds form a hollow sphere, and the one or more agent is encapsulated within the hollow sphere; and wherein the one or more agent is non-covalently associated with the cyclic polysaccharide compound, optionally further comprising a surfactant. The particles may comprise one or more additional drug. The invention further relates to pharmaceutical, cosmetic, or nutraceutical use of the particles.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 19, 2023
    Applicant: Veri Nano Inc.
    Inventors: Guillermo U. RUIZ ESPARZA HERRERA, Kanny CHANG, Ketian ZHANG, Samson AFEWERKI
  • Patent number: 11168050
    Abstract: The present invention relates generally to an eco-friendly methodology for the conversion of alcohols and aldehydes to amines and amides using an integrated enzyme cascade system with metal- and organocatalysis. More specifically, the present invention relates to synthesis of capsaicinoids starting from vanillin alcohol and using a combination of an enzyme cascade system and catalysts. Furthermore, the method also relates to synthesis of capsaicinoids derivatives starting from vanillin alcohol derivatives and using a combination of an enzyme cascade system and catalysts.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: November 9, 2021
    Assignee: XP Chemistries AB
    Inventors: Armando Córdova, Per Berglund, Mattias Anderson, Samson Afewerki
  • Patent number: 10995154
    Abstract: The present disclosure relates to the environmentally preparation of nanocellulose and derivatives thereof. The invention further relates to the preparation of cellulose derivatives.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: May 4, 2021
    Assignee: Organofuel Sweden AB
    Inventors: Armando Córdova, Samson Afewerki
  • Patent number: 10611702
    Abstract: Embodiments herein concerns the eco-friendly conversion of simple alcohols to linear or branched functionalized alkanes, by integrated catalysis. The alcohols are firstlyoxidized either chemically or enzymatically to the corresponding aldehydes or ketones, followed by aldol condensations using a catalyst to give the corresponding enals or enones. The enals or enones are subsequently and selectively hydrogenated using a recyclable heterogeneous metal catalyst, organocatalyst or an enzyme to provide linear or branched functionalized alkanes with an aldehyde, keto- or alcohol functionality. The process is also iterative and can be further extended by repeating the above integrated catalysis for producing long-chain functionalized alkanes from simple alcohols.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: April 7, 2020
    Assignee: Organofuel Sweden AB
    Inventors: Armando Córdova, Samson Afewerki
  • Publication number: 20190210940
    Abstract: Embodiments herein concerns the eco-friendly conversion of simple alcohols to linear or branched functionalized alkanes, by integrated catalysis. The alcohols are firstlyoxidized either chemically or enzymatically to the corresponding aldehydes or ketones, followed by aldol condensations using a catalyst to give the corresponding enals or enones. The enals or enones are subsequently and selectively hydrogenated using a recyclable heterogeneous metal catalyst, organocatalyst or an enzyme to provide linear or branched functionalized alkanes with an aldehyde, keto- or alcohol functionality. The process is also iterative and can be further extended by repeating the above integrated catalysis for producing long-chain functionalized alkanes from simple alcohols.
    Type: Application
    Filed: August 16, 2017
    Publication date: July 11, 2019
    Inventors: Armando Córdova, Samson Afewerki
  • Patent number: 10308588
    Abstract: A mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalyst and amine donor is disclosed. The initial heterogeneous metal-catalyzed reaction between the carbonyl and the amine donor components is followed by the addition of a suitable acylating agent component in one-pot, thus providing a catalytic one-pot three-component synthesis of amides. Integration of enzyme catalysis allows for eco-friendly one-pot co-catalytic synthesis of amides from aldehyde and ketone substrates, respectively. The process can be applied to asymmetric synthesis or to the co-catalytic one-pot three-component synthesis of capsaicin and its analogues from vanillin or vanillyl alcohol. A co-catalytic reductive amination/dynamic kinetic resolution (dkr) relay sequence for the asymmetric synthesis of optically active amides from ketones is disclosed.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: June 4, 2019
    Assignee: ORGANOFUEL SWEDEN AB
    Inventors: Armando Córdova, Carlos Palo-Nieto, Samson Afewerki
  • Patent number: 10287226
    Abstract: A method of reducing a C—O bond to the corresponding C—H bond in a substrate, which could be a benzylic alcohol, allylic alcohol, ester or an ether bond beta to a hydroxyl group or alpha to a carbonyl group using a recyclable metal catalyst system. The recyclable catalyst system is also applicable to reducing a C?O bond to the corresponding C—OH bond and then C—H bond. These methodologies can be linked in one-pot to selective oxidation and depolymerizations of aromatic polyols such as lignin.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 14, 2019
    Assignee: ORGANOFUEL SWEDEN AB
    Inventors: Armando Córdova, Samson Afewerki, Carlos Palo-Nieto
  • Publication number: 20180346607
    Abstract: The present disclosure relates to the environmentally preparation of nanocellulose and derivatives thereof. The invention further relates to the preparation of cellulose derivatives.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 6, 2018
    Inventors: Armando Córdova, Samson Afewerki
  • Publication number: 20170362162
    Abstract: A mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalyst and amine donor is disclosed. The initial heterogeneous metal-catalyzed reaction between the carbonyl and the amine donor components is followed by the addition of a suitable acylating agent component in one-pot, thus providing a catalytic one-pot three-component synthesis of amides. Integration of enzyme catalysis allows for eco-friendly one-pot co-catalytic synthesis of amides from aldehyde and ketone substrates, respectively. The process can be applied to asymmetric synthesis or to the co-catalytic one-pot three-component synthesis of capsaicin and its analogues from vanillin or vanillyl alcohol. A co-catalytic reductive amination/dynamic kinetic resolution (dkr) relay sequence for the asymmetric synthesis of optically active amides from ketones is disclosed.
    Type: Application
    Filed: December 15, 2015
    Publication date: December 21, 2017
    Applicant: ORGANOFUEL SWEDEN AB
    Inventors: Armando CÓRDOVA, Carlos PALO-NIETO, Samson AFEWERKI
  • Publication number: 20170334819
    Abstract: A method of reducing a C—O bond to the corresponding C—H bond in a substrate, which could be a benzylic alcohol, allylic alcohol, ester or an ether bond beta to a hydroxyl group or alpha to a carbonyl group using a recyclable metal catalyst system. The recyclable catalyst system is also applicable to reducing a C?O bond to the corresponding C—OH bond and then C—H bond. These methodologies can be linked in one-pot to selective oxidation and depolymerizations of aromatic polyols such as lignin.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 23, 2017
    Applicant: ORGANOFUEL SWEDEN AB
    Inventors: Armando CÓRDOVA, Samson AFEWERKI, Carlos PALO-NIETO
  • Publication number: 20170174618
    Abstract: The present invention relates generally to an eco-friendly methodology for the conversion of alcohols and aldehydes to amines and amides using an integrated enzyme cascade system with metal- and organocatalysis. More specifically, the present invention relates to synthesis of capsaicinoids starting from vanillin alcohol and using a combination of an enzyme cascade system and catalysts. Furthermore, the method also relates to synthesis of capsaicinoids derivatives starting from vanillin alcohol derivatives and using a combination of an enzyme cascade system and catalysts.
    Type: Application
    Filed: March 27, 2015
    Publication date: June 22, 2017
    Inventors: Armando CÓRDOVA, Per BERGLUND, Mattias ANDERSON, Samson AFEWERKI