Patents by Inventor Samuel D. Bernal

Samuel D. Bernal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting and killing epithelial cancer cells
    Patent number: 6649144
    Abstract: A diagnostic method for detecting cancerous epithelial cells by selectively marking the mitochondria of the cancer cells, by delivering to the epithelium a cationic supravital mitochondrial marking agent. Selective killing of cancerous epithelial cells in the presence of normal cells is effected by delivering a cationic supravital mitochondrial marking agent to epithelial cancer cells. The killing agent can also comprise the reaction product of the marking agent and a cancer chemotherapeutic drug.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: November 18, 2003
    Assignee: Zila, Inc.
    Inventors: Douglas D. Burkett, Ralph E. Green, Samuel D. Bernal
  • Method for detecting and killing epithelial cancer cells
    Publication number: 20030017158
    Abstract: A diagnostic method for detecting cancerous epithelial cells by selectively marking the mitochondria of the cancer cells, by delivering to the epithelium a cationic supravital mitochondrial marking agent. Selective killing of cancerous epithelial cells in the presence of normal cells is effected by delivering a cationic supravital mitochondrial marking agent to epithelial cancer cells.
    Type: Application
    Filed: March 8, 2002
    Publication date: January 23, 2003
    Inventors: Samuel D. Bernal, Douglas D. Burkett, Ralph E. Green, Seth D. Rose
  • Monoclonal antibody with specificity to human small cell carcinoma and use thereof
    Patent number: 4585742
    Abstract: Monoclonal antibody reactive with SCC cells and unreactive with human neuroblastoma cells, human squamous cell carcinoma cells, and human large-cell undifferentiated lung carcinoma cells.
    Type: Grant
    Filed: December 14, 1983
    Date of Patent: April 29, 1986
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventor: Samuel D. Bernal