Patents by Inventor Samuel Huang

Samuel Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12084653
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Grant
    Filed: January 27, 2023
    Date of Patent: September 10, 2024
    Assignee: Oregon Health & Science University
    Inventors: Hiroyuki Nakai, Samuel Huang, Kei Adachi
  • Patent number: 12084654
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Grant
    Filed: January 27, 2023
    Date of Patent: September 10, 2024
    Assignee: Oregon Health & Science University
    Inventors: Hiroyuki Nakai, Samuel Huang, Kei Adachi
  • Publication number: 20230287404
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Application
    Filed: January 27, 2023
    Publication date: September 14, 2023
    Inventors: Hiroyuki NAKAI, Samuel HUANG, Kei ADACHI
  • Publication number: 20230287405
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Application
    Filed: January 27, 2023
    Publication date: September 14, 2023
    Inventors: Hiroyuki NAKAI, Samuel HUANG, Kei ADACHI
  • Publication number: 20230193315
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods. This disclosure also provides novel AAV capsid mutants. TRADE technology was used to identify novel AAV vectors that mediate neuronal transduction in the brain following intravenous administration. Application of TRADE in vivo resulted in the identification of new AAV capsids that can transduce neurons more efficiently and more specifically than AAV9 in the brain following administration of the new AAV capsids. The disclosed methods may be used to identify AAV capsids that target various cell populations.
    Type: Application
    Filed: January 31, 2020
    Publication date: June 22, 2023
    Inventors: Hiroyuki NAKAI, Samuel HUANG, Kei ADACHI
  • Publication number: 20230119163
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Application
    Filed: August 24, 2022
    Publication date: April 20, 2023
    Inventors: Hiroyuki NAKAI, Samuel HUANG, Kei ADACHI
  • Patent number: 11459558
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: October 4, 2022
    Assignee: Oregon Health & Science University
    Inventors: Hiroyuki Nakai, Samuel Huang, Kei Adachi
  • Publication number: 20210348160
    Abstract: Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods.
    Type: Application
    Filed: June 2, 2021
    Publication date: November 11, 2021
    Inventors: Hiroyuki NAKAI, Samuel HUANG, Kei ADACHI
  • Publication number: 20160045422
    Abstract: Provided are compositions comprising a gloss agent having a refractive index of 1.4 or greater, an emollient film facilitator having a viscosity of 300 cPs or greater, and a film-forming polymer, wherein the composition comprises a greater amount, on a weight percent basis, of emollient film facilitator than gloss agent. Also provided are methods of providing radiance to the skin by applying to the skin a composition of the present invention.
    Type: Application
    Filed: May 14, 2012
    Publication date: February 18, 2016
    Applicant: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Samuel HUANG, Lydia ZENG, Amigo GU, Linda ZHANG, Jiang WU
  • Publication number: 20070190099
    Abstract: A bioactive material is made using fibroin solutions and suspensions designed to support the constructions, repair, regeneration or augmentation of bone and other tissues of the body. The fibroin solutions, suspensions, and composites can be injected to fill cavities or to replace missing tissue. After injection, the materials can produce a scaffold capable of promoting tissue regeneration while degrading. The ability to inject the fibroin solutions, suspensions and composites can reduce the need for many types of surgical procedures that are used to replace or repair bone and other tissues. The fibroin solutions and suspensions are particularly useful for methods of tissue construction and/or repair.
    Type: Application
    Filed: April 5, 2007
    Publication date: August 16, 2007
    Applicant: THE UNIVERSITY OF CONNECTICUT
    Inventors: Anthony DiBenedetto, Samuel Huang, Claudio Migliaresi, Antonella Motta
  • Publication number: 20070037727
    Abstract: A foaming cleansing preparation and system that produce a high quality, self-sustaining foam immediately upon exposure to water without physical agitation or rubbing is provided. The inventive cleansing preparation is made up of at least one dry acid, at least one dry base, and at least one liquid film-forming cleansing agent. When the cleansing preparation is exposed to water, the acid(s) and the base(s) will react to form a gas and the cleansing agent(s) will form a liquid film, and the gas and the liquid film will then interact to form or generate a foam. The inventive cleansing system is made up of a plurality of delivery particles, with each such delivery particle containing one or more components of the inventive cleansing preparation.
    Type: Application
    Filed: August 10, 2005
    Publication date: February 15, 2007
    Inventors: Robert Fiore, Samuel Huang
  • Publication number: 20030099682
    Abstract: A tissue/implant interface, comprising an implant and a bioactive polymer layer adjacent at least a portion of the outer surface of the implant, wherein the polymer layer contains at least one tissue response modifier covalently attached to the polymer layer or entrapped within the polymer layer in a quantity effective to control the tissue response at the site of implantation. Preferably, the at least one tissue response modifier controls inflammation, fibrosis, and/or neovascularization. Exemplary tissue response modifiers include, but are not limited to, steroidal and non-steroidal anti-inflammatory agents, anti-fibrotic agents, anti-proliferative agents, cytokines, cytokine inhibitors, neutralizing antibodies, adhesive ligands, and combinations thereof. Use of the various combinations of tissue response modifiers with bioactive polymers provides a simple, flexible and effective means to control the implant/tissue interphase, improving implant lifetime and function.
    Type: Application
    Filed: January 31, 2002
    Publication date: May 29, 2003
    Inventors: Francis Moussy, Donald Kreutzer, Diane Burgess, Jeffrey Koberstein, Fotios Papadimitrakopoulos, Samuel Huang
  • Patent number: 6515040
    Abstract: Polyamides, polyesters, and polyamideesters are efficiently synthesized in a microwave process with precise temperature control. Compared to conventional thermal polymerizations, the microwave process takes less time and produces polymers with equivalent or superior physical properties.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: February 4, 2003
    Assignee: The University of Connecticut
    Inventors: Daniel A. Scola, Xiaomei Fang, Samuel Huang, Eleonora Vaccaro
  • Patent number: 6497729
    Abstract: A tissue/implant interface, comprising an implant and a bioactive polymer layer adjacent at least a portion of the outer surface of the implant, wherein the polymer layer contains at least one tissue response modifier covalently attached to the polymer layer or entrapped within the polymer layer in a quantity effective to control the tissue response at the site of implantation. Preferably, the at least one tissue response modifier controls inflammation, fibrosis, and/or neovascularization. Exemplary tissue response modifiers include, but are not limited to, steroidal and non-steroidal anti-inflammatory agents, anti-fibrotic agents, anti-proliferative agents, cytokines, cytokine inhibitors, neutralizing antibodies, adhesive ligands, and combinations thereof. Use of the various combinations of tissue response modifiers with bioactive polymers provides a simple, flexible and effective means to control the implant/tissue interphase, improving implant lifetime and function.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: December 24, 2002
    Assignee: The University of Connecticut
    Inventors: Francis Moussy, Donald Kreutzer, Diane Burgess, Jeffrey Koberstein, Fotios Papadimitrakopoulos, Samuel Huang