Patents by Inventor Samuel Pendergraft

Samuel Pendergraft has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing in vitro testicular constructs and uses thereof
    Patent number: 10993433
    Abstract: A cell composition composed of spermatogonial stem cells, Sertoli cells, Leydig cells and optionally peritubular cells, is provided, as is a culture composition, artificial testicular construct, hydrogel composition, and device containing the same. A method for using the device as a physiologically relevant in vitro model of human testicular function to screen compounds for pharmacological or toxicological activity is also provided.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: May 4, 2021
    Assignee: Wake Forest University Health Sciences
    Inventors: Samuel Pendergraft, Hooman Sadri-Ardekani, Anthony Atala, Colin Bishop
  • METHOD OF PRODUCING IN VITRO TESTICULAR CONSTRUCTS AND USES THEREOF
    Publication number: 20170107483
    Abstract: A cell composition composed of spermatogonial stem cells, Sertoli cells, Leydig cells and optionally peritubular cells, is provided, as is a culture composition, artificial testicular construct, hydrogel composition, and device containing the same. A method for using the device as a physiologically relevant in vitro model of human testicular function to screen compounds for pharmacological or toxicological activity is also provided.
    Type: Application
    Filed: October 14, 2016
    Publication date: April 20, 2017
    Inventors: Samuel Pendergraft, Hooman Sadri-Ardekani, Anthony Atala, Colin Bishop