Abstract: A port monitoring system including: a port environment detection unit in which it is important to monitor the accurate position and posture of ships, especially large ships, in a port (or harbor), and which monitors the position and status of fenders in the port, and measures the environmental conditions of the port and thus generates port environment information to integrally manage ships and fenders in order to efficiently manage the port; a ship monitoring unit which is included in a ship and generates ship information of the ship; a fender monitoring unit which is included in a fender and generates fender information of the fender; a network; and a port management unit.

Abstract: A pneumatic fender includes: a ring-shaped metal fitting housing that is mounted on at least one end of a pneumatic fender and forms a penetrating part penetrating the inside and outside of the pneumatic fender; a plate-shaped flange that is mounted on the penetrating part to block the inside and outside of the pneumatic fender; a wireless transmitter that is mounted on the front surface of the flange defining a surface formed in the external direction of the pneumatic fender; a cover that is mounted on the front surface of the flange; a shaft that has a predetermined length and is mounted on the rear surface of the flange; a position sensor that is mounted on the internal direction end of the shaft and generates position information of the pneumatic fender; and a reflective member that is connected to the shaft between the flange and the position sensor.

Abstract: Disclosed herein is an insulating bushing adapted to protect a busbar and having improved waterproof performance. The insulating bushing includes: a first bushing provided with a first bushing passage through which the busbar passes; a second bushing provided with a first bushing-receiving portion receiving an upper portion of the first bushing inserted through a lower portion of the first bushing-receiving portion and a second bushing passage through which the busbar passes; and a cover coupled to an outer surface of the second bushing and provided with a cover passage through which the busbar passes.

Abstract: Provided are a composition for expressing and/or producing a polypeptide of interest in an animal cell, comprising a target-specific endonuclease system or an encoding gene thereof and a donor DNA structure; a recombinant animal cell into which said composition is introduced and a manufacturing method thereof; and a method for expressing and/or producing a polypeptide of interest in an animal cell, comprising a step of introducing said composition into the animal cell and/or a step of culturing said animal cell.

Abstract: The present invention relates to a method for producing a cell having a genetic defect corrected, and a cell therapy agent comprising the cell, and, more particularly, to a method for producing a cell and a cell therapy agent comprising the cell, which comprise a method for isolating a cell from an individual, producing a chemically derived progenitor cell by processing a compound, and then correcting a mutant gene ex vivo. The cell therapy agent of the present invention has significantly less side effects such as an off-target effect and tumor generation, and has shown a Tyrosinemia type I treatment effect that is more significant than when a simple cell is transplanted, and thus, the cell therapy agent is expected to be widely usable in treatment fields for diseases caused by gene mutation, including Tyrosinemia type I.

Abstract: Disclosed herein is an insulating bushing adapted to protect a busbar and having improved waterproof performance. The insulating bushing includes: a first bushing provided with a first bushing passage through which the busbar passes; a second bushing provided with a first bushing-receiving portion receiving an upper portion of the first bushing inserted through a lower portion of the first bushing-receiving portion and a second bushing passage through which the busbar passes; and a cover coupled to an outer surface of the second bushing and provided with a cover passage through which the busbar passes.

Abstract: The present disclosure relates to a method for detecting off-target sites of a programmable nuclease in a genome, and specifically, to a method for detecting off-target sites through data analysis by subjecting the genome isolated in vitro to programmable nucleases to cleave the genome and then performing whole genome sequencing or deep sequencing, and to a method for selecting on-target sites of a programmable nuclease, which minimizes the off-target effect, using this method. The Digenome-seq of the present disclosure can detect the off-target sites of a programmable nuclease on the genomic scale at a high degree of reproducibility, and thus can be used in the manufacture of programmable nucleases having high target specificity and the study thereof.

Abstract: A new alga having an improved ability to produce a pigment is disclosed. When the alga is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. The pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. Since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO.

Abstract: A new alga having an improved ability to produce a pigment is disclosed. When the new alga is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. The pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. Since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

Abstract: A new alga having an improved ability to produce a pigment is disclosed. When the alga is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. The pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. Since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO.

Abstract: A new alga having an improved ability to produce a pigment is disclosed. When the new alga is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. The pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. Since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

Abstract: The present invention relates to a new alga having an improved ability to produce a pigment, and when a mutant of the present invention is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. Further, the pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. In particular, since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

Abstract: The present disclosure relates to a method for detecting off-target sites of a programmable nuclease in a genome, and specifically, to a method for detecting off-target sites through data analysis by subjecting the genome isolated in vitro to programmable nucleases to cleave the genome and then performing whole genome sequencing or deep sequencing, and to a method for selecting on-target sites of a programmable nuclease, which minimizes the off-target effect, using this method. The Digenome-seq of the present disclosure can detect the off-target sites of a programmable nuclease on the genomic scale at a high degree of reproducibility, and thus can be used in the manufacture of programmable nucleases having high target specificity and the study thereof.

Abstract: The present invention relates to a new alga having an improved ability to produce a pigment, and when a mutant of the present invention is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. Further, the pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. In particular, since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

Abstract: The present invention relates to a method of selecting a nuclease target sequence for gene knockout based on microhomology.

Abstract: Provided are an abrasion-detection type conveyor belt and a manufacturing method thereof. A polymer composition ratio of is set to 40-60% of styrene-butadiene rubber (SBR) and 60-40% of natural rubber (NR), and an adhesive strength between a cover rubber layer and an abrasion-detection color layer is set to 13 kN/m (33 kgf/inch). As compared to the existing product, material properties of the abrasion-detection color layer are improved to extend the available life of the abrasion detection type conveyor belt. The abrasion-detection type conveyor belt is cost-effective, simplifies a belt line, and reduces an inspection time.

Abstract: Provided are an abrasion-detection type conveyor belt and a manufacturing method thereof A polymer composition ratio of is set to 40-60% of styrene-butadiene rubber (SBR) and 60-40% of natural rubber (NR), and an adhesive strength between a cover rubber layer and an abrasion-detection color layer is set to 13 kN/m (33 kgf/inch). As compared to the existing product, material properties of the abrasion-detection color layer are improved to extend the available life of the abrasion detection type conveyor belt. The abrasion-detection type conveyor belt is cost-effective, simplifies a belt line, and reduces an inspection time.