Patents by Inventor Sarah Melissa Gruba
Sarah Melissa Gruba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11850422Abstract: Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit and control circuitry configured to control delivery of the one or more electric fields from the electric field generating circuit to the site of the cancerous tissue. An implantable lead is included having a lead body including a first electrical conductor disposed within the lead body, and a first electrode coupled to the lead body, the first electrode in electrical communication with the first electrical conductor, wherein the first electrical conductor forms part of an electrical circuit by which the electric fields from the electric field generating circuit are delivered to the site of the cancerous tissue, and the first electrode can include a conductive coil filar disposed around the lead body. Other embodiments are also included herein.Type: GrantFiled: April 22, 2020Date of Patent: December 26, 2023Assignee: Boston Scientific Scimed, Inc.Inventors: Brian L Schmidt, Devon N. Arnholt, Keith R. Maile, Sarah Melissa Gruba, William J. Linder
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Patent number: 11420049Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, including an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor and control circuitry in communication with the electric field generating circuit. The medical device includes one or more supply wires in electrical communication with the electric field generating circuit and one or more supply electrodes. The supply electrodes are configured to deliver an electric field at or near the site of the cancerous tumor. The medical device can include one or more sensing wires in electrical communication with the control circuitry and one or more sensing electrodes. The sensing electrodes can be configured to measure an impedance of the cancerous tumor at at least two different electric field strengths. Other embodiments are also included herein.Type: GrantFiled: April 16, 2020Date of Patent: August 23, 2022Assignee: Boston Scientific Scimed, Inc.Inventors: Brian L. Schmidt, Benjamin Keith Stein, Keith R. Maile, William J. Linder, Ron A. Balczewski, Sarah Melissa Gruba, Tucker James Nelson, Aleksandra Kharam
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Publication number: 20220249676Abstract: A chemotherapy agent comprising a chemotherapy group and a ligand secured to the chemotherapy group is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing chemotherapy agents from a patient is disclosed, the method comprising providing a chemotherapy agent containing a reactive group; providing a capture substrate in contact with a patient's bloodstream; administering the chemotherapy agent to the patient; and sequestering the chemotherapy agent on the capture substrate. A system for removing chemotherapy agents is also disclosed.Type: ApplicationFiled: May 11, 2020Publication date: August 11, 2022Inventors: Joseph Thomas Delaney, JR., Sarah Melissa Gruba, Tatyana Dyndikova, Paul Vincent Grosso, Amanda Maxwell, Ajay Gupta, Andrew J. Ro, Douglas Pennington
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Patent number: 11213596Abstract: An imaging contrast composition comprising an iodinated contrast agent and a ligand secured to the iodinated contrast agent is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing iodinated radiocontrast agents from a patient is disclosed, the method comprising providing an iodinated radiocontrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the iodinated radiocontrast agent to the patient; conducting procedure CT scan or procedure using fluoroscopy; and sequestering the iodinated radiocontrast agent on the capture substrate.Type: GrantFiled: February 14, 2019Date of Patent: January 4, 2022Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph Thomas Delaney, Jr., Douglas Dean Pagoria, Richard Lee Tadsen, Andrew J. Ro, Joel T. Eggert, Douglas Pennington, Paul Sorajja, Sarah Melissa Gruba, Tatyana Dyndikova
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Publication number: 20210308450Abstract: A medical device comprising a tube, a first electrode and a second electrode, and a structure at a distal portion of the tube, the structure defining a first section and a second section, wherein the first and second sections are configured to be filled with a conductive medium, wherein the first electrode is contained within the first section, and the second electrode is contained within the second section, and wherein the structure includes a central barrier separating the first section from the second section, and the central barrier is insulative.Type: ApplicationFiled: March 31, 2021Publication date: October 7, 2021Applicant: Boston Scientific Scimed, Inc.Inventors: Sarah Melissa GRUBA, Troy Anthony GIESE, James A. KLOS, James P. ROHL
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Publication number: 20200338345Abstract: Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit and control circuitry configured to control delivery of the one or more electric fields from the electric field generating circuit to the site of the cancerous tissue. An implantable lead is included having a lead body including a first electrical conductor disposed within the lead body, and a first electrode coupled to the lead body, the first electrode in electrical communication with the first electrical conductor, wherein the first electrical conductor forms part of an electrical circuit by which the electric fields from the electric field generating circuit are delivered to the site of the cancerous tissue, and the first electrode can include a conductive coil filar disposed around the lead body. Other embodiments are also included herein.Type: ApplicationFiled: April 22, 2020Publication date: October 29, 2020Inventors: Brian L. Schmidt, Devon N. Arnholt, Keith R. Maile, Sarah Melissa Gruba, William J. Linder
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Publication number: 20200330757Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, including an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor and control circuitry in communication with the electric field generating circuit. The medical device includes one or more supply wires in electrical communication with the electric field generating circuit and one or more supply electrodes. The supply electrodes are configured to deliver an electric field at or near the site of the cancerous tumor. The medical device can include one or more sensing wires in electrical communication with the control circuitry and one or more sensing electrodes. The sensing electrodes can be configured to measure an impedance of the cancerous tumor at at least two different electric field strengths. Other embodiments are also included herein.Type: ApplicationFiled: April 16, 2020Publication date: October 22, 2020Inventors: Brian L. Schmidt, Benjamin Keith Stein, Keith R. Maile, William J. Linder, Ron A. Balczewski, Sarah Melissa Gruba, Tucker James Nelson, Aleksandra Kharam
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Patent number: 10667896Abstract: The disclosure pertains to percutaneously deliverable bioabsorbable closure devices for an ostium of a left atrial appendage which devices promote endothelialization across the ostium and then are bioabsorbed to leave little or no foreign residue, methods of manufacturing such bioabsorbable closure devices, and the use thereof.Type: GrantFiled: November 11, 2016Date of Patent: June 2, 2020Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph Thomas Delaney, Jr., David Robert Wulfman, Sarah Melissa Gruba
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Publication number: 20200008870Abstract: An example medical system for ablating and occluding the left atrial appendage is disclosed. The example system includes a catheter sized and shaped for vascular access and including an elongate body extending between a proximal end and a distal end. A first expandable member may be positioned near the distal end of the elongate body and have a first region configured to permeate a liquid therethrough. A first set of one or more electrodes may be arranged within the first expandable member and may be configured to deliver energy to the tissue region. An occlusive implant may be releasably secured to the distal end of the elongate body.Type: ApplicationFiled: July 9, 2019Publication date: January 9, 2020Applicants: BOSTON SCIENTIFIC SCIMED, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: SARAH MELISSA GRUBA, JAMES P. ROHL, JAMES A. KLOS, JOHN M. EDGELL, DOUGLAS DEAN PAGORIA, SAMUEL J. ASIRVATHAM
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Publication number: 20190275178Abstract: An imaging contrast composition comprising an iodinated contrast agent and a ligand secured to the iodinated contrast agent is disclosed, the ligand comprising a reactive group capable of bonding to a capture substrate. A method of removing iodinated radiocontrast agents from a patient is disclosed, the method comprising providing an iodinated radiocontrast agent containing a reactive group; providing a capture substrate for insertion into a patient's bloodstream; administering the iodinated radiocontrast agent to the patient; conducting procedure CT scan or procedure using fluoroscopy; and sequestering the iodinated radiocontrast agent on the capture substrate.Type: ApplicationFiled: February 14, 2019Publication date: September 12, 2019Inventors: Joseph Thomas Delaney, Douglas Dean Pagoria, Richard Lee Tadsen, Andrew J. Ro, Joel T. Eggert, Douglas Pennington, Paul Sorajja, Sarah Melissa Gruba, Tatyana Dyndikova
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Publication number: 20170135801Abstract: The disclosure pertains to percutaneously deliverable bioabsorbable closure devices for an ostium of a left atrial appendage which devices promote endothelialization across the ostium and then are bioabsorbed to leave little or no foreign residue, methods of manufacturing such bioabsorbable closure devices, and the use thereof.Type: ApplicationFiled: November 11, 2016Publication date: May 18, 2017Applicant: CARDIAC PACEMAKERS, INC.Inventors: Joseph Thomas Delaney, Jr., David Robert Wulfman, Sarah Melissa Gruba