Patents by Inventor Sarah Stanley

Sarah Stanley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for the treatment of mycobacterial infections
    Patent number: 9682064
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: June 20, 2017
    Assignees: The Broad Institute, Inc., Massachusetts General Hospital
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
    Publication number: 20170014378
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Application
    Filed: July 21, 2016
    Publication date: January 19, 2017
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • Compositions and Methods to Modulate Cell Activity
    Publication number: 20160346391
    Abstract: The present invention provides methods and compositions for the remote control of cell function based on the use of radiofrequency waves to excite nanoparticles targeted to specific cell types. The nanoparticles may be applied to the target cell extracellularly and/or expressed intracellularly. The cell type of interest expresses a temperature sensitive channel wherein excitation of the nanoparticles results in a localized temperature increase that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject. Accordingly, the invention provides a generic approach for treatment of any disease associated with a protein deficiency.
    Type: Application
    Filed: May 31, 2016
    Publication date: December 1, 2016
    Inventors: Jeffrey Friedman, Sarah Stanley
  • Compounds for the treatment of mycobacterial infections
    Patent number: 9416121
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: August 16, 2016
    Assignees: The Broad Institute, Inc., Massachusetts General Hospital
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • Compositions and methods to modulate cell activity
    Patent number: 9399063
    Abstract: The present invention provides methods and compositions for the remote control of cell function based on the use of radiofrequency waves to excite nanoparticles targeted to specific cell types. The nanoparticles may be applied to the target cell extracellularly and/or expressed intracellularly. The cell type of interest expresses a temperature sensitive channel wherein excitation of the nanoparticles results in a localized temperature increase that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject. Accordingly, the invention provides a generic approach for treatment of any disease associated with a protein deficiency.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: July 26, 2016
    Assignee: THE ROCKEFELLER UNIVERSITY
    Inventors: Jeffrey Friedman, Sarah Stanley
  • COMPOSITIONS AND METHODS TO MODULATE CELL ACTIVITY
    Publication number: 20140348825
    Abstract: The present invention provides methods and compositions for the remote control of cell function based on the use of radiofrequency waves to excite nanoparticles targeted to specific cell types. The nanoparticles may be applied to the target cell extracellularly and/or expressed intracellularly. The cell type of interest expresses a temperature sensitive channel wherein excitation of the nanoparticles results in a localized temperature increase that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject. Accordingly, the invention provides a generic approach for treatment of any disease associated with a protein deficiency.
    Type: Application
    Filed: August 24, 2012
    Publication date: November 27, 2014
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Jeffrey Friedman, Sarah Stanley
  • COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
    Publication number: 20140296232
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Application
    Filed: March 27, 2014
    Publication date: October 2, 2014
    Applicants: Massachusetts General Hospital, The Broad Institute, Inc.
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu