Patents by Inventor Sathy Balu-Iyer

Sathy Balu-Iyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphoserine containing compositions for immune tolerance induction
    Patent number: 11701328
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: July 18, 2023
    Assignee: The Research Foundation for The State University of New York
    Inventors: Sathy Balu-Iyer, Richard Bankert, Radha Ramakrishnan, Robert Dingman, Vandana Iyer, Jennifer Schneider, Fiona Yau Glassman, Nhan Hanh Nguyen
  • COMPOSITIONS AND METHODS FOR REDUCING ANTIGEN-SPECIFIC IMMUNOGENICITY
    Publication number: 20220016241
    Abstract: Provided are methods for inducing immune tolerance to antigens including therapeutic antigens. The present methods comprise administering to an individual OPLS or other lipidic compositions and the antigen, either in a single formulation or as separate formulations where the separate formulations are administered concomitantly or sequentially.
    Type: Application
    Filed: July 27, 2021
    Publication date: January 20, 2022
    Inventors: Sathy Balu-Iyer, Matthew Pierson Kosloski, Krithika Arun Shetty, Jennifer Leigh Schneider, Anas M. Fathallah
  • PHOSPHOSERINE CONTAINING COMPOSITIONS FOR IMMUNE TOLERANCE INDUCTION
    Publication number: 20210353726
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Application
    Filed: July 28, 2021
    Publication date: November 18, 2021
    Inventors: Sathy BALU-IYER, Richard BANKERT, Radha RAMAKRISHNAN, Robert DINGMAN, Vandana IYER, Jennifer SCHNEIDER, Fiona YAU GLASSMAN, Nhan Hanh NGUYEN
  • Phosphoserine containing compositions for immune tolerance induction
    Patent number: 11083782
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: August 10, 2021
    Assignee: The Research Foundation for The State University of New York
    Inventors: Sathy Balu-Iyer, Richard Bankert, Radha Ramakrishnan, Robert Dingman, Vandana Iyer, Jennifer Schneider, Fiona Yau Glassman, Nhan Hanh Nguyen
  • PHOSPHOSERINE CONTAINING COMPOSITIONS FOR IMMUNE TOLERANCE INDUCTION
    Publication number: 20200222322
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 16, 2020
    Inventors: Sathy Balu-Iyer, Richard Bankert, Radha Ramakrishnan, Robert Dingman, Vandana Iyer, Jennifer Schneider, Fiona Yau Glassman, Nhan Hanh Nguyen
  • Phosphoserine containing compositions for immune tolerance induction
    Patent number: 10617640
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: April 14, 2020
    Assignee: The Research Foundation for The State University of New York
    Inventors: Sathy Balu-Iyer, Richard Bankert, Radha Ramakrishnan, Robert Dingman, Vandana Iyer, Jennifer Schneider, Fiona Yau Glassman, Nhan Hanh Nguyen
  • PHOSPHOSERINE CONTAINING COMPOSITIONS FOR IMMUNE TOLERANCE INDUCTION
    Publication number: 20190151426
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Application
    Filed: April 5, 2017
    Publication date: May 23, 2019
    Inventors: Sathy BALU-IYER, Richard BANKERT, Radha RAMAKRISHNAN, Robert DINGMAN, Vandana IYER, Jennifer SCHNEIDER, Fiona YAU, Nhan Hanh NGUYEN
  • PHOSPHOSERINE CONTAINING COMPOSITIONS FOR IMMUNE TOLERANCE INDUCTION
    Publication number: 20170209371
    Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.
    Type: Application
    Filed: April 5, 2017
    Publication date: July 27, 2017
    Inventors: Sathy Balu-Iyer, Richard Bankert, Radha Ramakrishnan, Robert Dingman, Vandana Iyer, Jennifer Schneider, Fiona Yau, Nhan Hanh NGUYEN
  • COMPOSITIONS AND METHODS FOR REDUCING ANTIGEN-SPECIFIC IMMUNOGENICITY
    Publication number: 20160243220
    Abstract: Provided are method for inducing immune tolerance to antigens including therapeutic antigens. The method comprises administering to an individual OPLS or other lipidic compositions and the antigen, either in a single formulation or as separate formulations where the separate formulations are administered concomitantly or sequentially.
    Type: Application
    Filed: September 24, 2014
    Publication date: August 25, 2016
    Inventors: Sathy Balu-Iyer, Matthew Pierson Kosloski, Krithika Arun Shetty, Jennifer Leigh Schneider, Anas M. Fathallah
  • Compositions of less immunogenic and long-circulating protein-lipid complexes
    Publication number: 20070274980
    Abstract: Provided are lipidic particles comprising phopatidylcholine, phosphatidylinositol and cholesterol. Also provided are compositions comprising the lipidic particles and having associated therewith therapeutic agents such as peptides, polypeptides or proteins. In these compositions, the therapeutic agents have reduced immunogenicity and/or longer circulating time. These compositions can be used for therapeutic administration of the peptides, polypeptides and/or proteins.
    Type: Application
    Filed: March 30, 2007
    Publication date: November 29, 2007
    Inventors: Sathy Balu-Iyer, Robert Straubinger, Razvan Miclea, Aaron Peng
  • Method for treating blood coagulation disorders
    Publication number: 20070275050
    Abstract: Provided is a method for treatment of blood coagulation disorders. The method comprises administering to an individual compositions comprising lipidic particles comprising phopatidylcholine, phosphatidylinositol and cholesterol. One or more peptides, polypeptides or proteins involved in the blood coagulation cascade are associated with the lipidic particles.
    Type: Application
    Filed: March 30, 2007
    Publication date: November 29, 2007
    Inventors: Sathy Balu-Iyer, Robert Straubinger, Razvan Miclea, Aaron Peng
  • Compositions and methods of preparation of liposomal microparticulate IL-12
    Publication number: 20070071804
    Abstract: This invention provides methods and compositions for localized delivery of IL-12 to a desired site. The composition comprises liposomes carrying IL-12. The liposomes comprise phosphatidyl choline, phosphatidyl glycerol and cholesterol. The size and composition of the liposomes is such that there is minimal leakage into the systemic circulation. These compositions can be used for delivery of IL-12 to selected sites such as tumors.
    Type: Application
    Filed: August 9, 2006
    Publication date: March 29, 2007
    Inventors: Sathy Balu-Iyer, Richard Bankert, Vivek Purohit
  • Lipid nano particulates containing antigens as cancer vaccines
    Publication number: 20070059318
    Abstract: The present invention provides compositions and method for increasing the immunogenicity of antigens such as tumor antigens. The compositions comprise liposomes such that they are suitable for targeting denderitic cells. The compositions preferably comprise at least 50% liposomes which are less than 120 nm. The liposomes comprise a cationic lipid and phosphatidyl choline. The antigen is intercalated within or in the bilayer or covalently linked to the liposomal molecules.
    Type: Application
    Filed: August 15, 2006
    Publication date: March 15, 2007
    Inventors: Sathy Balu-Iyer, Richard Bankert