Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: A game system includes a mode switching unit switching a play mode between a one-player play mode and a two-player play mode, on the basis of at least one of first operation data from a left controller and second operation data from a right controller, and a control unit controlling a player character and a sub-player character in a virtual space. In the one-player play mode, the control unit switches an operation target between the player character and the sub-player character is set as an operation target, on the basis of the first operation data and the second operation data, and in the two-player play mode, the control unit controls the player character on the basis of the first operation data and controls the sub-player character on the basis of the second operation data.

Abstract: A game system includes a mode switching unit switching a play mode between a one-player play mode and a two-player play mode, on the basis of at least one of first operation data from a left controller and second operation data from a right controller, and a control unit controlling a player character and a sub-player character in a virtual space. In the one-player play mode, the control unit switches an operation target between the player character and the sub-player character is set as an operation target, on the basis of the first operation data and the second operation data, and in the two-player play mode, the control unit controls the player character on the basis of the first operation data and controls the sub-player character on the basis of the second operation data.

Abstract: An example of an information processing system displays, on a display device, a plurality of panoramic images associated with locations on a map. Here, a predetermined virtual object is set for at least one of the plurality of panoramic images. an information processing system 1 determines one of the locations on the map as a current location based on a user operation. Where the virtual object is set for a panoramic image associated with the current location, the virtual object is placed at a predetermined position of the panoramic image. The information processing system 1 displays, on the display device, an image of a partial area of the panoramic image associated with the current location. A predetermined information process is performed in response to satisfaction of a predetermined condition regarding the virtual object while the panoramic image for which the virtual object is set is displayed.

Abstract: A first information processing apparatus executes an application, and generates control data in accordance with a state of an execution of the application. The control data is transmitted to a second information processing apparatus. Video data is stored in advance in the second information processing apparatus. The second information processing apparatus receives the control data transmitted from the first information processing apparatus, determines a video to be reproduced based on the control data, and reproduces the video based on the video data.

Abstract: A method for generating a stereoscopic panorama image may include acquiring panorama images respectively captured by three or more panorama cameras located in a real space. A left-eye image and a right-eye image for stereoscopic display may be generated by synthesizing parts of the acquired panorama images. The generated left-eye image and the generated right-eye image may be displayed stereoscopically on a display.

Abstract: A non-limiting example game apparatus includes a CPU, and the CPU performs a non-contact communication with an IC tag that is incorporated in a figure by using a non-contact communication module. When card information data is read from each of two figures (EEPROM incorporated in the IC tag) and the same card object is set usable, for example, the card object concerned is changed to a special card object. That is, a special card object is produced.

Abstract: A game apparatus includes a CPU, and in a mode of examining a flower based on an imaged image, the CPU activates two outward cameras to allow a user to image a flower. The CPU obtains color information, shape information and a size of the imaged flower from the imaged image. A shape category is obtained from the shape information, and with the shape category, data for search included in a database for search is filtered. Then, by comparing color information, shape information, and the size of the imaged flower with the data for search to be used, a score of a degree of approximation of the color information and scores of the degree of matching of the shape information and size, etc. are obtained. Then, images of flowers as candidates are presented in the descending order of the score (similarity level).

Abstract: A left panorama image and a right panorama image respectively captured by a left panorama camera and a right panorama camera are acquired. A rearward image area, of a rearward area, included in the right panorama image and captured by the right panorama camera is synthesized to the left panorama image, instead of a rearward image area, of the rearward area, included in the left panorama image and captured by the left panorama camera, to generate a left-eye image. The rearward image area, of the rearward area, included in the left panorama image and captured by the left panorama camera is synthesized to the right panorama image, instead of the rearward image area, of the rearward area, included in the right panorama image and captured by the right panorama camera, to generate a right-eye image.

Abstract: A game apparatus includes a CPU, and when a virtual game is started, the CPU generates game image data and displays a corresponding game screen on a monitor. In the game screen, an operating instruction describing operation procedure is displayed and contents of the instruction changes according to a progress of the game. For example, as the game advances, an operating instruction including how to perform a new operation is displayed when a player object learns a new attack, or when a level (experience) of the player object increases or an operation level of the player increases. However, if the virtual game has not been played for a relatively long period of time, the operating instruction is displayed regardless of the progress of the game.

Abstract: An example of an information processing system displays, on a display device, a plurality of panoramic images associated with locations on a map. Here, a predetermined virtual object is set for at least one of the plurality of panoramic images. an information processing system 1 determines one of the locations on the map as a current location based on a user operation. Where the virtual object is set for a panoramic image associated with the current location, the virtual object is placed at a predetermined position of the panoramic image. The information processing system 1 displays, on the display device, an image of a partial area of the panoramic image associated with the current location. A predetermined information process is performed in response to satisfaction of a predetermined condition regarding the virtual object while the panoramic image for which the virtual object is set is displayed.

Abstract: A game apparatus includes a first LCD and a second LCD. The first LCD and the second LCD are arranged in either side of a predetermined axis. A computer of the game apparatus respectively displays a first character image and a second character image on the first LCD and the second LCD, and further respectively displays a first message image and a second message image on the first LCD and the second LCD. Then, in response to a predetermined operation performed via a touch panel, etc., at least one of the first message image and the second message image respectively displayed on the first LCD and the second LCD is updated.

Abstract: An example of an information processing system includes a plurality of information processing apparatuses each capable of displaying, on a display device, a plurality of panoramic images associated with points on a map. A transmission-side apparatus determines a target point on the basis of an operation of a user, and displays, on a first display device, an image of a partial area, corresponding to a line-of-sight direction determined in accordance with an operation of the user, of a panoramic image associated with the target point. The transmission-side apparatus stores path information regarding a path along which the target point is moved during a predetermined period. A reception-side apparatus acquires the two or more panoramic images identified by the path information stored in the transmission-side apparatus, and displays, on a second display device, the acquired two or more panoramic images in an order identified by the path information.

Abstract: Panorama images respectively captured by three or more panorama cameras located in a real space are acquired. A left-eye image and a right-eye image are generated by synthesizing parts of the acquired panorama images.

Abstract: A left panorama image and a right panorama image respectively captured by a left panorama camera and a right panorama camera are acquired. A rearward image area, of a rearward area, included in the right panorama image and captured by the right panorama camera is synthesized to the left panorama image, instead of a rearward image area, of the rearward area, included in the left panorama image and captured by the left panorama camera, to generate a left-eye image. The rearward image area, of the rearward area, included in the left panorama image and captured by the left panorama camera is synthesized to the right panorama image, instead of the rearward image area, of the rearward area, included in the right panorama image and captured by the right panorama camera, to generate a right-eye image.

Abstract: An example of a game apparatus includes a CPU, and in a mode of examining a flower based on an imaged image, the CPU activates two outward cameras to thereby display an imaging screen on a stereoscopic LCD and a lower LCD. In the center of an upper screen displayed on the stereoscopic LCD, a designation image for adjusting a position and a size of an object to be imaged is displayed. Also, on the upper screen, a through image imaged by the outward camera is displayed, and the designation image is displayed in front of the through image. At this time, the designation image is displayed in a complementary color of a color of the through image.

Abstract: An image display system that has access to a display unit capable of stereoscopic display is provided. The image display system includes a background setting unit for setting a two-dimensional stereo image for stereoscopic view as a background; a reference surface setting unit for setting a reference surface in a virtual space such that the reference surface corresponds to a pseudo-surface that appears to exist in the two-dimensional stereo image when the two-dimensional stereo image is stereoscopically displayed; an object placing unit for placing at least an object on the reference surface; a stereoscopic image creating unit for creating an image for stereoscopic view, based on a stereo image created by picking-up an image of the object using a stereo virtual camera in the virtual space and on the two-dimensional stereo image; and a display control unit for causing the display unit to display the image for stereoscopic view.

Abstract: An example of a game apparatus includes a CPU. The CPU activates two outward cameras to allow a user to image, for example, a flower. The CPU filters data for search included in a database. The CPU obtains color information, shape information and a size of the imaged flower. A shape category is obtained, and with the shape category, data for search included in a database for search is further filtered. Then, by comparing the color information, the shape information, and the size of the imaged flower with the data for search to be used, a score of a degree of approximation of the color information and scores of the degree of matching of the shape information and size, etc. are obtained. Then, images of flowers as candidates are presented in the descending order of the score (similarity level).

Abstract: A game apparatus stores a history in relation to a game operation as replay data in a memory, and displays a replay image on the basis of the stored replay data on a monitor. A CPU of the game apparatus creates highlight scene positional information indicating a at least temporal position of a highlight scene in the replay image on the basis of a highlight scene position designating operation, stores the created highlight scene positional information by bringing it into association with the replay data in the memory, and displays a time-line image representing a temporal position of the highlight scene in the replay image on the monitor on the basis of the highlight scene positional information when the replay image is displayed on the monitor.

Abstract: An example of a game apparatus includes a CPU, and in a mode of examining a flower based on an imaged image, the CPU activates two outward cameras to thereby display an imaging screen on a stereoscopic LCD and a lower LCD. In the center of an upper screen displayed on the stereoscopic LCD, a designation image for adjusting a position and a size of an object to be imaged is displayed. Also, on the upper screen, a through image imaged by the outward camera is displayed, and the designation image is displayed in front of the through image. At this time, the designation image is displayed in a complementary color of a color of the through image.