Patents by Inventor Satu Vainikka
Satu Vainikka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240099267Abstract: The object of the present invention is a hoof boot shell part (1) comprising a base part (2), the lower surface of which (2a) is arranged to rest against a surface and the upper surface of which (2b) is arranged to receive the bottom of the hoof. A rim (3) is arranged to extend from the edge of the base part (2) and adapted in use to surround the hoof. Attached to the lower surface (2a) of the base part (2) is a bottom piece (10), which forms an area (10a) of the lower surface (2a) of the base part (2), which is harder compared with the hardness of the other material of the base part (2).Type: ApplicationFiled: June 29, 2023Publication date: March 28, 2024Applicant: Vainica OyInventors: Satu Vainikka, Jiri Vainikka
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Patent number: 10400008Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].Type: GrantFiled: April 30, 2014Date of Patent: September 3, 2019Assignee: Cancer Research Technology LimitedInventors: Satu Vainikka, George Steven Morris, Samuel Ogunsalu, Gabriella Castoria, Antimo Migliaccio, Ferdinando Auricchio
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Publication number: 20180273585Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.Type: ApplicationFiled: March 19, 2018Publication date: September 27, 2018Inventors: Mark Eccleston, Satu Vainikka, George Steven Morris
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Patent number: 10023612Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynecological condition in which an activity of AR and/or ER is a contributory factor in a subject.Type: GrantFiled: November 1, 2012Date of Patent: July 17, 2018Assignee: VALIRX PLCInventors: Mark Eccleston, Satu Vainikka, George Steven Morris
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Publication number: 20160068568Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].Type: ApplicationFiled: April 30, 2014Publication date: March 10, 2016Inventors: Satu Vainikka, George Steven Morris, Samuel Ogunsalu, Gabriella Castoria, Antimo Migliaccio, Fernando Auricchio
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Publication number: 20140322306Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.Type: ApplicationFiled: November 1, 2012Publication date: October 30, 2014Inventors: Mark Eccleston, Satu Vainikka, George Steven Morris
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Publication number: 20120077270Abstract: A method for suppressing the expression of a selected gene in a cell, the method comprising introducing into the cell a molecule comprising (1) a nucleic acid binding portion which binds to a site or associated with the selected gene which site is present in a genome and (2) an expression repressor portion, wherein the nucleic acid binding portion comprises an oligonucleotide or oligonucleotide mimic or analogue, and wherein the repressor portion comprises a polypeptide or peptidomimetic. Molecules for use in the methods of the invention are provided. The repressor may be a portion of a histone deacetylase or DNA methylase or polypeptide capable of recruiting a histone deacetylase or DNA methylase.Type: ApplicationFiled: October 3, 2011Publication date: March 29, 2012Applicant: IMPERIAL COLLEGE INNOVATIONS LIMITEDInventors: Stephen Hart, Simak Ali, Boris Tumi PuFong, Andrew C.G. Porter, Laki Buluwela, Satu Vainikka, John David Jenkinson, Patrick Kanda
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Publication number: 20090082250Abstract: A method for suppressing the expression of a selected gene in a cell the method comprising introducing into the cell a molecule comprising (1) a nucleic acid binding portion which binds to a site or associated with the selected gene which site is present in a genome and (2) an expression repressor portion, wherein the nucleic acid binding portion comprises an oligonucleotide or oligonucleotide mimic or analogue, and wherein the repressor portion comprises a polypeptide or peptidomimetic. Molecules for use in the methods of the invention are provided. The repressor may be a portion of a histone deacetylase or DNA methylase or polypeptide capable of recruiting a histone deacetylase or DNA methylase.Type: ApplicationFiled: May 13, 2008Publication date: March 26, 2009Applicant: IMPERIAL COLLEGEINNOVATIONS LIMITEDInventors: Stephen Hart, Simak Ali, Boris Tumi PuFong, Andrew C. G. Porter, Laki Buluwela, Satu Vainikka, John David Jenkinson, Patrick Kanda
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Publication number: 20060247192Abstract: A method for suppressing the expression of a selected apoptosis-related gene in a cell the method comprising introducing into the cell a molecule comprising (1) a nucleic acid binding portion which binds to a site at or associated with the selected gene which site is present in a genome and (2) a modifying portion, wherein the nucleic acid binding portion comprises an oligonucleotide or oligonucleotide mimic or analogue, and wherein the repressor portion comprises a polypeptide or peptidomimetic. Molecules for use in the methods of the invention are provided. The repressor or modifying portion may be a portion of a histone deacetylase or DNA methylase or polypeptide capable of recruiting a histone deacetylase or DNA methylase. The nucleic acid binding portion may be a triplex forming oligonucleotide (TFO). The apoptosis-related gene may be Bcl-2.Type: ApplicationFiled: December 5, 2003Publication date: November 2, 2006Inventors: John Jenkinson, Patrick Kanda, Satu Vainikka
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Publication number: 20050136040Abstract: A method for suppressing the expression of a selected gene in a cell the method comprising introducing into the cell a molecule comprising (1) a nucleic acid binding portion which binds to a site or associated with the selected gene which site is present in a genome and (2) an expression repressor portion, wherein the nucleic acid binding portion comprises an oligonucleotide or oligonucleotide mimic or analogue, and wherein the repressor portion comprises a polypeptide or peptidomimetic. Molecules for use in the methods of the invention are provided. The repressor may be a portion of a histone deacetylase or DNA methylase or polypeptide capable of recruiting a histone deacetylase or DNA methylase.Type: ApplicationFiled: April 8, 2004Publication date: June 23, 2005Applicant: Imperial College Innovations LimitedInventors: Stephen Hart, Simak Ali, Boris PuFong, Andrew Porter, Laki Buluwela, Satu Vainikka, John Jenkinson, Patrick Kanda
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Patent number: D974674Type: GrantFiled: September 1, 2021Date of Patent: January 3, 2023Assignee: Vainica OyInventor: Satu Vainikka