Patents by Inventor Satwant K. Narula

Satwant K. Narula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAMMALIAN CYTOKINES; RELATED REAGENTS AND METHODS
    Publication number: 20140335094
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: July 14, 2014
    Publication date: November 13, 2014
    Inventors: Birgit Oppmann, Rene de Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • Mammalian Cytokines; Related Reagents and Methods
    Publication number: 20110177022
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: January 4, 2011
    Publication date: July 21, 2011
    Applicant: Schering Corporation
    Inventors: Birgit Oppmann, Rene de Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • IL-12P40 and IL-B30 polypeptide complex
    Patent number: 7883695
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: February 8, 2011
    Assignee: Schering Corporation
    Inventors: Birgit Oppmann, Rene de Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • Mammalian genes; related reagents and methods
    Patent number: 7183382
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: February 27, 2007
    Assignee: Schering Corporation
    Inventors: Birgit Oppmann, Rene De Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • Mammalian cytokines; related reagents and methods
    Patent number: 7090847
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: September 8, 2000
    Date of Patent: August 15, 2006
    Assignee: Schering Corporation
    Inventors: Birgit Oppmann, Rene De Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • Mammalian cytokines; related reagents and methods
    Publication number: 20030162261
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: February 27, 2003
    Publication date: August 28, 2003
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Birgit Oppmann, Rene De Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • Novel uses of mammalian CCR6 receptors and related reagents
    Publication number: 20020138860
    Abstract: Compositions and methods for using mammalian CCR6 and MIP-3&agr; proteins to treat an abnormal physiological condition in an individual. The methods comprise administering a therapeutically effective amount of CCR6 or MIP-3&agr; alone, or in combination with other therapeutic reagents; or a CCR6 or MIP-3&agr; antagonist. Genetically-engineered animals and their use as models of molecular mechanism are also provided.
    Type: Application
    Filed: March 20, 2002
    Publication date: September 26, 2002
    Inventors: Donald Cook, Sergio A. Lira, Satwant K. Narula
  • Materials and methods for screening human interleukin-4 antagonists/agonists
    Patent number: 6200805
    Abstract: Stably-transformed human cell lines containing a reporter gene operatively linked to an IL-4-responsive element are provided. In some embodiments a human Fc&egr;RII IL-4-responsive element is used. In other embodiments a human germline &egr; transcript promoter is used as the responsive element. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human interleukin-4.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: March 13, 2001
    Assignee: Schering Corporation
    Inventors: Jan E. de Vries, Chung-Her Jenh, Satwant K. Narula, Paul J. Zavodny
  • Method for treating or preventing ischemia-reperfusion injury
    Patent number: 6086868
    Abstract: There is disclosed a method of treating ischemia-reperfusion injury comprising administering an effective amount of Interleukin-10 to a patient suffering or expected to suffer from such injury.
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: July 11, 2000
    Assignee: Schering Corporation
    Inventors: Lyle L. Moldawer, James M. Seeger, Timothy R. S. Harward, Satwant K. Narula
  • Human gamma interferon antagonist/agonist screen
    Patent number: 6001560
    Abstract: Stably-transformed human cell lines containing a human gamma interferon-responsive human HLA-DR.alpha. promoter operatively linked to a reporter gene are provided. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human gamma interferon.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: December 14, 1999
    Assignee: Schering Corporation
    Inventors: Herinder K. Lonial, Satwant K. Narula, Paul J. Zavodny
  • Human interleukin-4 antagonist/agonist screens
    Patent number: 5958707
    Abstract: Stably-transformed human cell lines containing a reporter gene operatively linked to an IL-4-responsive element are provided. In some embodiments a human Fc.sub..epsilon. RII IL-4-responsive element is used. In other embodiments a human germline .epsilon. transcript promoter is used as the responsive element. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human interleukin-4.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: September 28, 1999
    Assignee: Schering Corporation
    Inventors: Jan E. de Vries, Chung-Her Jenh, Satwant K. Narula, Paul J. Zavodny
  • Method for treating inflammation
    Patent number: 5753218
    Abstract: A method is provided for treating or preventing inflammatory conditions, in particular septic shock and inflammatory conditions caused by auto-immune diseases, such as inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, uveitis, and psoriasis. The method comprises administering to a mammal a therapeutically effective amount of IL-10 plus at least one steroid such as betamethasone. Also provided are pharmaceutical compositions and kits comprising IL-10 plus at least one steroid, e.g., betamethasone or its derivatives.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: May 19, 1998
    Assignee: Schering Corporation
    Inventors: Sidney R. Smith, Satwant K. Narula
  • E. coli secretory strains
    Patent number: 5578464
    Abstract: Strains of E. coli are provided which are capable of secreting heterologous recombinant proteins through the outer cell wall and directly into the culture medium. Methods are also provided for making and identifying such strains, and for using them to make heterologous proteins that have high biological activity, without the need for cell disruption.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: November 26, 1996
    Assignee: Schering Corporation
    Inventors: Charles A. Lunn, Satwant K. Narula, Richard L. Reim
  • Expression systems utilizing bacteriophage T7 promoters, gene sequences, and T7 RNA polymerase
    Patent number: 5122457
    Abstract: Expression systems which utilize bacteriophage T7 RNA mutant polymerases and promoter regions are provided by this invention. These systems are utilized to produce large quantities of useful polypeptides and proteins.
    Type: Grant
    Filed: October 19, 1989
    Date of Patent: June 16, 1992
    Assignee: Schering Corporation
    Inventors: Richard L. Reim, Satwant K. Narula, Michael J. Ryan, Paul J. Leibowitz