Abstract: The invention provides a method of assessing the potential color protecting effect in vivo of a test formulation such as rinse-off hair treatment formulation, the method comprising the steps of: providing a sample of the test formulation to be assessed; providing a model substrate in the form of a hair switch which has been artificially colored; applying the test formulation to the hair switch; subsequently rinsing the test formulation from the hair switch; collecting the rinse liquor and analysing it for the presence of eluted color; characterized in that the artificial color used to color the hair switch is a permanent hair colorant with a shade level 1 or 2 according to the International Color Chart (I.C.C.). The method provides improved sensitivity and differentiation, and enables the tester to compare different technologies in terms of effectiveness.

Abstract: The storage of events of multiple types in a queriable table. The queriable table has at least one common column that corresponds to a field that is common across events regardless of event type. The queriable table also has at least one field-varying column that corresponds to a type-dependent field that depends on event type. The queriable table is populated using multiple events. For instance, the event could be at least some log events that are received from multiple computing systems. The population occurs by assigning each event to a row of the queriable table. The common column is populated with values taken the same common field across event types. On the other hand, the field-varying column is populated with values of different fields from those events depending on the event type.

Abstract: The present invention provides compounds of Formula (I): wherein A, Y and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: A non-invasive thermal dispersion flow meter with chronometric monitor for fluid leak detection includes a heater, an ambient temperature sensor and a flow rate sensor which are configured to sense the temperature of a fluid in a conduit, and then monitor the flow of that fluid through the conduit. Based upon the ambient temperature sensor readings, the flow rate sensor and heater may be adjusted to optimize the operation of the system to detect leaks. Based on the sensor readings, the flow may be adjusted to prevent damage and leaks by relieving the system of excess pressure. Geographic location, occupancy sensors and occupant identifiers are used to control the system to facilitate operation and minimize leak damage when occupants are away.

Abstract: The invention provides a personal cleansing composition comprising, in an aqueous continuous phase: (i) from 5 to 30% by weight of one or more anionic cleansing surfactants; (ii) microcapsules in which a core comprising benefit agent is encapsulated in a polymeric shell, and (iii) a combination of cationic polymers comprising: (a) at least one cationic polygalactomannan having a mean charge density at pH7 of less than 1.2 meq per gram, preferably from 0.5 to 1.1; and (b) at least one cationic polygalactomannan having a mean charge density at pH7 at least 1.2 meq per gram, preferably from 1.2 to 3, more preferably from 1.2 to 2.

Abstract: The invention provides a personal cleansing composition comprising, in an aqueous continuous phase: (i) from 5 to 30% by weight of one or more anionic cleansing surfactants; (ii) from 0.1 to 10% by weight of discrete, dispersed droplets of emulsified silicone with a mean diameter (D3,2) of 4 micrometres or less; (iii) from 0.1 to 5% by weight of microcapsules in which a core comprising benefit agent is encapsulated in a polymeric shell, and (iv) from 0.1 to 0.5% by weight of a combination of cationic polymers comprising: (a) at least one cationic polygalactomannan derivative having a mean charge density at pH 7 from 0.2 to 2 meq per gram; and (b) at least one acrylamidopropyltrimonium chloride/acrylamide copolymer having a mean charge density at pH 7 from 1 to 3 meq per gram.

Abstract: The present invention provides compounds of Formula (I): wherein A is as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: The present invention provides compounds of Formula (I): wherein A is as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

Abstract: The present invention provides compounds of Formula (I): wherein A is as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: The present invention provides compounds of Formula (I): wherein A, Y and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: A non-invasive thermal dispersion flow meter with chronometric monitor for fluid leak detection includes a heater, an ambient temperature sensor and a flow rate sensor which are configured to sense the temperature of a fluid in a conduit, and then monitor the flow of that fluid through the conduit. The fluid flow sensor is incorporated into a Wheatstone bridge circuit, which is used to provide increased sensitivity to the outputs of the sensors. Based upon the ambient temperature sensor readings, the flow rate sensor and heater may be adjusted to optimize the operation of the system to detect leaks. An alternative embodiment utilizes a single sensor and separate heater which work together to determine heat propagation times which in turn is used to calculate flow rate. Based on the sensor readings, the flow may be adjusted to prevent damage and leaks by relieving the system of excess pressure.

Abstract: An input device having a sensing region overlapping an input surface includes a first substrate, a second substrate physically coupled to the first substrate, and a sensor electrode disposed on the first substrate and configured to detect input objects in the sensing region. A first force sensor includes a first electrode disposed on the first substrate and a first conductive portion of the second substrate capacitively coupled with the first electrode. The first conductive portion is configured to move relative to the first electrode such that a first variable capacitance of the first force sensor changes in response to force applied to the input surface in a first direction parallel to the touch surface.

Abstract: The present invention provides compounds of Formula (I): wherein A and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: A non-invasive thermal dispersion flow meter with chronometric monitor for fluid leak detection includes a heater, an ambient temperature sensor and a flow rate sensor which are configured to sense the temperature of a fluid in a conduit, and then monitor the flow of that fluid through the conduit. The fluid flow sensor is incorporated into a Wheatstone bridge circuit which is used to provide increased sensitivity to the outputs of the sensors. Based upon the ambient temperature sensor readings, the flow rate sensor and heater may be adjusted to optimize the operation of the system to detect leaks. An alternative embodiment utilizes a single sensor and separate heater which work together to determine heat propagation times which in turn is used to calculate flow rate. Based on the sensor readings, the flow may be adjusted to prevent damage and leaks by relieving the system of excess pressure.

Abstract: The present invention provides compounds of Formula (I): wherein A and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

Abstract: A non-invasive thermal dispersion flow meter with chronometric monitor for fluid leak detection includes a heater, an ambient temperature sensor and a flow rate sensor which are configured to sense the temperature of a fluid in a conduit, and then monitor the flow of that fluid through the conduit. The fluid flow sensor is incorporated into a Wheatstone bridge circuit, which is used to provide increased sensitivity to the outputs of the sensors, Based upon the ambient temperature sensor readings, the flow rate sensor and heater may be adjusted to optimize the operation of the system to detect leaks. An alternative embodiment utilizes a single sensor and separate heater which work together to determine heat propagation times which in turn is used to calculate flow rate. Based on the sensor readings, the flow may be adjusted to prevent damage and leaks by relieving the system of excess pressure.

Abstract: A non-invasive thermal dispersion flow meter with chronometric monitor for fluid leak detection includes a heater, an ambient temperature sensor and a flow rate sensor which are configured to sense the temperature of a fluid in a conduit, and then monitor the flow of that fluid through the conduit. The fluid flow sensor is incorporated into a Wheatstone bridge circuit which is used to provide increased sensitivity to the outputs of the sensors. Based upon the ambient temperature sensor readings, the flow rate sensor and heater may be adjusted to optimize the operation of the system to detect leaks. An alternative embodiment utilizes a single sensor and separate heater which work together to determine heat propagation times which in turn is used to calculate flow rate. Based on the sensor readings, the flow may be adjusted to prevent damage and leaks by relieving the system of excess pressure.

Abstract: An ultra-thin wearable sensing device includes a sensor tag IC that enables the device to communicate wirelessly to a reading device. The wearable sensing device includes one or more sensors connected to the sensor tag IC that sense characteristics of the person, animal or object that the sensing device comes in contact with. The sensed characteristics can include biological signals (e.g., ECG, EMG, and EEG), temperature, galvanic skin response (GSR), heat flux and chemicals or fluids released by the skin. The reading device can display the information to the user and/or transmit the sensor data to a remote location for further processing. A doctor can review the data or have the data further analyzed and use this data or information to assist with treatment.

Abstract: An insulator inspection tool and method for identifying defects or conditions that may prevent the insulator from performing properly is disclosed. The apparatus includes a launcher adapted to launch a projectile towards an insulator being tested, a listening device adapted to receive a response signal from the insulator upon being struck by the projectile, and a processing device adapted to measure the response signal received by the listening device and process the response signal to determine whether the insulator contains any defects or conditions.