Abstract: The invention provides 1,2-substituted cyclic compounds useful for treatment of diseases or disorders arising from abnormal or inappropriate cell proliferation, such as tumour growth, tumour metastasis and associated angiogenesis, as well as pharmaceutical compositions comprising these compounds and their use in methods of treatment.

Abstract: A self-propelled personal watercraft is disclosed, wherein the personal watercraft includes a body including a hull and a deck substantially covering the hull, wherein the body includes a bow portion and a stern portion. The personal watercraft also includes a deck modification module removably attached to the deck, wherein the deck modification module is configured to be selectively removable to change a performance characteristic of the deck when the deck is submerged in water.

Abstract: Use of a polylysine, polyamidoamine or polypropylenimine dendrimer having naphthyl disulphonate terminal groups as a topically applied agent in prophylaxis or treatment of sexually transmitted diseases.

Abstract: The system maintains both a document-centric and a data-centric representation of data gathered during the ingest stage. Data ingest may be by internal instrument data capture, external data capture and/or manual data capture. Data is managed in a query-able form; communication among data processing modules is effected using XML. The system allows data to be cast to and from a variety of different domain-specific representations, for consumption by a variety of different domain-specific analysis stages.

Abstract: An axillary thermometer for measuring the temperature of a patient comprising a first disk-shaped member having a circumferential edge, and an upper portion and lower portion, that is integrally connected, and angularly situated, via a connecting member joint, to a second disk-shaped member having a top side and a bottom side. The top side of the second disk-shaped member, including an actuation switch and display, being proximate the upper portion of the first disk-shaped member such that viewing of the temperature display can be simultaneously accomplished with the temperature taking process. The first disk-shaped member further having at least one temperature sensor along its circumferential edge of the upper portion with the at least one temperature sensor being connected to at least one temperature sensing circuitry.

Abstract: A capturing and viewing appliance and method are used for capturing and communicating images. The capturing and viewing appliance is an instrument used to capture and communicate images to other devices with communication capabilities. The capturing and viewing appliance includes a processor for manipulating and viewing the images on a built-in display. Program code stored in internal memory includes a menu/image navigation application program which allows the user to use navigation buttons to view multiple images as well as navigate menus. According to another aspect of the invention, the menu/image navigation interface provides a user-friendly interface for effective communication of functionality of an appliance or other device to the user through use of animated transitions.

Abstract: An apparatus for molding an optical lens from a molten thermoplastic resin material using an injection molding machine, and including means for forming a mold cavity defined by a pair of opposed, spaced apart inserts shaped and configured to define opposite faces of said optical lens and having a plurality of overflow wells surrounding the mold cavity means for injecting a predetermined optimum volume of resin material into said mold cavity; means for controllably moving at least one insert relative to the other insert, wherein such relative insert motion is driven by a power cylinder capable of providing a variable compression stroke during molding and is initiated prior to completion of said injection; means for controlling the velocity and/or compressive force of the compression stroke of said power cylinder such that said compression is conducted at a first selected relatively high velocity, thus urging excess resin from said cavity into said overflow wells after which the compression force is varied to a

Abstract: A drain stopper includes a suction cup. The drain stopper is configured to block a drain opening and prevent water from entering the drain. The suction cup allows the drain stopper to be stored on a variety of surfaces, such as a vertical bathtub wall. In one form, the suction cup is on the bottom of the drain stopper and fits within the drain opening.

Abstract: A portable folding chair features a seat and a back that are joined in a hinged or pivoting fashion. A pair of front legs and a pair of rear legs are pivotally attached to the bottom of the seat. A track featuring elongated slots is also attached to the bottom of the seat. Front and rear leg braces are pivotally attached to the front and rear legs, respectively. The leg braces slide within the elongated slots of the track. The track is equipped with locking mechanisms so that the leg braces may be locked in the track with the legs in the open position. The back of the chair is equipped with a tab portion that forms a handle and extends down below the seat and engages a pair of angle bars that are included in the rear leg brace so that the back of the chair is secured in an open position. The legs may be folded against the bottom of the seat and the back rotated so that the legs and track are enclosed between the seat and back in a clamshell fashion.

Abstract: An apparatus is described that efficiently resupplies radioactive seeds to a brachytherapy applicator. A seed-holding system includes a holder and a transfer device. The holder, which may be disposable, stores the radioactive seeds and the transfer device, which may be reusable, helps shield and dispense the seeds. The holder is coupled to the transfer device, and the apparatus is mated to an applicator. After seeds have been dispensed, the apparatus may be disconnected from the applicator and the empty holder may be ejected from the transfer device, and replaced with a full holder.

Abstract: A toy for use by an infant in which the infant may set a top, suspended in pendulum fashion to a base, into motion. The top and base are joined by pendulum arms that cause a reciprocating gliding mechanism that is generally in the horizontal plane. The infant is positioned such that the infant may kick a pad joined to the fixed location base, initiating a force which propels the top to move back and forth providing entertainment and motor skills development.

Abstract: A spice grinding mill has a spice-containing jar with a collar on its neck carrying a frangible freshness seal which is removable to open the container. A grinding assembly is removably mountable on the container and has one or more manually operable latches engageable with keeper structure on the collar to releasably hold the grinding assembly in place, while permitting rotation of the outer portion of the grinding assembly relative to the container, which outer portion is covered with an elastomeric material for improved grip. A plastic cap is removably mountable on the collar or on the outlet of the grinding assembly.

Abstract: The invention relates to brachytherapy devices, methods for making brachytherapy devices, and methods for using brachytherapy devices. For example, the invention provides brachytherapy devices such as staging-sterilization devices and insert devices that can be used in various brachytherapy procedures.

Abstract: A molded plastic fixture has a core body formed of a relatively rigid first plastic material and an outer body covering outer surface portions of the core body and formed of an elastomeric material overmolded on the core body and providing improved gripping of supported articles and frictional surfaces to enhance grasping by a user. The fixture is mountable on a wall surface by one or more suction cups, which may be unitary with the outer body or may form part of a separate mounting structure engageable with the fixture in either pivoting or longitudinally sliding relationship therewith. The outer body may be light-transmitting to permit viewing therethrough of the core body, which may be formed of a visually distinguishable material.