Abstract: A carton for medicament storage includes a bottom box and a lid. The bottom box includes a bottom wall, a first sidewall, a second sidewall, a back wall, and a front wall. The carton also includes a lid coupled to the bottom box and movable between an open position and a closed position. The bottom box is closed by the lid when the lid is in the closed position. Additionally, the carton includes a release tab comprising a portion of the one of the lid and the second front wall and being defined by a perforated line in the one of the lid and the bottom box. The carton also may include an adhesive positioned on at least a part of the release tab and selectively coupling the lid and the bottom box. When the carton is in the closed position, the release tab is secured to the one of the lid and the bottom box via the perforation and is secured to the other of the lid and the bottom box via the adhesive.

Abstract: A multi-site injection system includes a plurality of medicament delivering needles/microprotrusions, a needle/microprotrusion support, a supply of medicament, and a mechanism for providing the medicament to the plurality of needles/microprotrusions in order to effect delivery into a stratum corneum of a user.

Abstract: A multi-site injection system includes a plurality of medicament delivering needles/microprotrusions, a needle/microprotrusion support, a supply of medicament, and a mechanism for providing the medicament to the plurality of needles/microprotrusions in order to effect delivery into a stratum corneum of a user.

Abstract: A multi-site injection system includes a plurality of medicament delivering needles/microprotrusions, a needle/microprotrusion support, a supply of medicament, and a mechanism for providing the medicament to the plurality of needles/microprotrusions in order to effect delivery into a stratum corneum of a user.

Abstract: A multi-site injection system includes a plurality of medicament delivering needles/microprotrusions, a needle/microprotrusion support, a supply of medicament, and a mechanism for providing the medicament to the plurality of needles/microprotrusions in order to effect delivery into a stratum corneum of a user.

Abstract: A multi-site injection system (10) in accordance with the present invention generally includes a plurality of medicament delivering needles/microprotrusions (18) along with a support therefore. A supply of medicament (36) is provided and a means provided for supplying the medicament to the plurality of needles/microprotrusions in order to effect delivery into a stratum corneum (42) of a user.

Abstract: The present invention relates to packaging materials for ophthalmic solutions. Difficulties with water loss in standard ophthalmic bottles are overcome in the controlled drop dispensing container of the present invention. This controlled drop dispensing container comprises a dispensing tip, a laminate tube 15, and a shoulder connecting the laminate tube 15 to the dispensing tip 7. The dispensing tip 7 comprises an inner orifice having a diameter sufficiently small to restrict flow of liquid contents of the tube to the desired level, an outer orifice 9 having a diameter sufficiently large to form a drop of the desired size from the liquid contents of the tube, where fluid communication exists between the inner orifice and the outer orifice 9. The laminate tube 15 comprises an outer polymeric layer 10, an optional first tie layer 11, a middle barrier layer 12, an optional second tie layer 13, an inner polymeric layer 14.

Abstract: A multi-site injection system (10) in accordance with the present invention generally includes a plurality of medicament delivering needles/microprotrusions (18) along with a support therefore. A supply of medicament (36) is provided and a means provided for supplying the medicament to the plurality of needles/microprotrusions in order to effect delivery into a stratum corneum (42) of a user.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: The present invention includes a method of intraocular delivery by needless injection of a medicament through the sclera of an eye and into a back of the eye as well as instruments for such delivery.

Abstract: A needleless microprotrusion method for infusion of a medicament into a patient includes disposing a substrate plurality of microprotrusions onto a patients' palm. A chemodenervating agent is disposed for delivery by the microprotrusions and the substrate supports and conforms the microprotrusions to the patients' palm in order to enable uniform penetration of the microprotrusions into the corneum.

Abstract: A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed for delivery by the microprotrusions and a substrate is provided for supporting the microprotrusions and conforming the microprotrusions to a patient's fossa axilaaris in order to enable uniform penetration of the microprotrusions into the corneum.

Abstract: A needleless injector generally includes a barrel having a proximal and a distal end and a bore therethrough along with an injection head disposed at the barrel distal end in fluid communication with the bore; an energy source is disposed at the barrel proximal end and a bolt may be disposed in said bore for reciprocating movement therein, from a first position to a second position for drawing medicament into the bore, the bolt being fitted in the bore in order to force medicament through the injection head upon movement of the bolt from the second to the first position. A mechanism is provided for activating the energy source in order to operate the bolt.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed for delivery by the microprotrusions and a substrate is provided for supporting the microprotrusions and conforming the microprotrusions to a patient's palm in order to enable uniform penetration of the microprotrusions into the corneum.

Abstract: An injection including a syringe having a barrel for containing a medicament, a shell for receiving the barrel with a needle projecting therefrom, a drive mechanism for moving a plunger disposed within the barrel, and a manually operative mechanism for moving the plunger in a stepwise manner to eject doses of the medicament from the barrel through the needle.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: A terminally sterilizable container includes a polypropylene bottle having a body with a manually squeezable sidewall and a thickness preventing water loss. The bottle body includes shoulders for providing autoclave produced pressure distribution and deformation resistance along with an elongated tips outfitted to a neck of the body and having a lumen therethrough with a drop dispensing orifice. A cap enclosed the elongated tip and includes enclosed with a nub for sealing the orifice to prevent autoclave produced pressure leaks.

Abstract: A controlled volume injection/aspiration device includes a syringe having a body for containing a medicament, a needle and a piston slidably disposed within the body. A shell is provided for receiving the syringe body and a plunger rack is disposed within the shell. A manually operated control is disposed in an operative relationship with the plunger rack for moving the plunger rack in a stepwise forward direction causing the piston to eject discrete doses of medication from the syringe body through the needle. The manual operated control is also operative for moving the piston in a stepwise reverse direction causing the piston to aspirate fluid into the syringe body through the needle.

Abstract: The present invention relates to packaging materials for ophthalmic solutions. Difficulties with water loss in standard ophthalmic bottles are overcome in the controlled drop dispensing container of the present invention. This controlled drop dispensing container comprises a dispensing tip, a laminate tube 15, and a shoulder connecting the laminate tube 15 to the dispensing tip 7. The dispensing tip 7 comprises an inner orifice having a diameter sufficiently small to restrict flow of liquid contents of the tube to the desired level, an outer orifice 9 having a diameter sufficiently large to form a drop of the desired size from the liquid contents of the tube, a means of enabling the liquid contents of the tube to move from the inner orifice to the outer orifice 9. The laminate tube 15 comprises an outer polymeric layer 10, an optional first tie layer 11, a middle barrier layer 12, an optional second tie layer 13, an inner polymeric layer 14.