Abstract: Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response, a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

Abstract: Methods and devices for classifying a cardiac response to pacing involve establishing a retriggerable cardiac response classification window. A first cardiac response classification window is established subsequent to delivery of a pacing pulse. A cardiac signal following the pacing stimulation is sensed in the first classification window. A second cardiac response classification may be triggered if a trigger characteristic is detected in the first classification window. The cardiac signal is sensed in the second classification window if the second classification window is established. The cardiac response to the pacing stimulation is determined based on characteristics of the cardiac signal. The cardiac response may be determined to be one of a captured response, a non-captured response, a non-captured response added to an intrinsic beat, and a fusion/pseudofusion beat, for example.

Abstract: An illuminated grab handle assembly is configured to connect to and illuminate a mounting surface. The assembly includes a housing having a body and a top cover. The body has a generally hollow shape and an open top portion that is covered and sealed by the top cover. A translucent window is positioned in the surface of the body and configured to allow light to pass from within the body to the mounting surface. A lighting element is positioned within the interior of the body and positioned to direct light out of the window and to the mounting surface.

Abstract: The present disclosure relates, according to some embodiments, to systems and methods for processing organic compounds, such as manure or other organic waste. Embodiments may comprise a first containment or mixing chamber, a first anaerobic chamber, and a second anaerobic chamber. A first anaerobic chamber may receive organic compounds from a first containment or mixing chamber, and may provide a fluid stream to a second anaerobic chamber. The second anaerobic chamber may comprise a substrate, such as lava rock, with bacteria growing thereon. Further, biogas generated in one or both of the first anaerobic chamber and the second anaerobic chamber may be purified in a first stage using a water scrubber to remove a majority of the carbon dioxide and other contaminants from the biogas, and in a second stage using a pressure swing adsorption unit to reduce carbon dioxide and other contaminants to pipeline acceptable levels.

Abstract: Systems and methods for improving ophthalmic imaging by correlating the location of a measurement on the pupil of the eye with a quality of the measurement and further controlling subsequent measurements based on the quality are presented. Aspects of the invention include obtaining optical coherence tomography (OCT) measurements through cataracts or other media opacities, obtaining B-scans with minimized tilt, and automated OCT data acquisition of select structures in the eye. Embodiments of the invention directed towards imaging tissues with angle dependent layer contrast and mapping the size and location of cataracts in the eye are also described.

Abstract: A method for calculating the power of an intraocular lens including measuring an axial separation between the front surface of the cornea and the plane of the iris root; and determining the power of the intraocular lens using the measured axial separation together with other measured parameters and empirically determined lens constants.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of identifying an activation time in a cardiac electrical signal. The method may include sensing a cardiac electrical signal, generating an approximation signal based at least in part on one or more parameters of the cardiac electrical signal, identifying a fiducial point on the approximation signal and determining, based at least in part on a timing of the fiducial point in the approximation signal, an activation time in the cardiac electrical signal.

Abstract: Medical devices and methods for making and using medical devices are disclosed. A method of mapping electrical activity of a heart may comprise sensing a plurality of signals with a plurality of electrodes positioned within the heart. The method may further comprise separating the plurality of signals into a first group of signals and a second group of signals, and generating a data set that includes at least one known data point and one or more unknown data points. In some examples, the at least one known data point is generated based on the first group of signals.

Abstract: Systems and method for creating crystalline parts having a desired primary and secondary crystallographic orientations are provided. One embodiment may take the form of a method of manufacturing a part having a crystalline structure. The method includes melting aluminum oxide and drawing the melted aluminum oxide up a slit. Additionally, the method includes orienting the seed crystal relative to a growth apparatus such that a crystalline structure grows having a desired primary plane and a desired secondary plane orientation. Moreover, the method includes pulling the crystal as it forms to create a ribbon shaped crystalline structure and cutting a part from the crystalline structure.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of mapping the electrical activity of a heart. The method may include sensing a plurality of signals with a plurality of electrodes positioned within the heart, determining a dominant frequency of the plurality of signals and generating an alternate signal for each of the plurality of signals corresponding to the dominant frequency. The alternate signals may have a phase-shift corresponding to one of the plurality of signals. The method may also include displaying a characteristic of the alternate signal over time.

Abstract: Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The catheter shaft may be coupled to a processor. The processor may be capable of collecting a first set of signals from a first location, collecting a second set of signals from a second location, characterizing the first set of signals over a first time period, characterizing the second set of signals over a second time period, comparing the first set of signals to the second set of signals and matching a first signal from the first set of signals with a second signal from the second set of signals.

Abstract: A cell culture device comprising a microscale chamber dimensioned to maintain a cell under conditions that give rise to a value for at least one pharmacokinetic parameter in vitro that is comparable to a value for the same at least one pharmacokinetic parameter obtained with respect to the same type of cell in vivo, wherein the microscale chamber is configured for flow of culture medium, and wherein the at least one pharmacokinetic parameter is selected from tissue size ratio, tissue to blood volume ratio, drug residence time, flow rate, circulatory transit time, liquid residence time, and liquid to cell ratio.

Abstract: Methods for displaying physiological mapping data are disclosed. An example method may include storing a set of three-dimensional positional data on a memory, storing a set of metric data on the memory, and storing a set of electrogram data on the memory. The method may also include outputting the set of three-dimensional positional data, the set of two-dimensional metric data, and the set of electrogram data from the memory to a display unit and displaying the set of three-dimensional positional data, the set of two-dimensional metric data, and the set of electrogram data on the display unit as a dynamic display.

Abstract: A supercharger outlet resonator comprises a housing, a first surface comprising a first opening and a housing axis bisecting the first opening, and a second surface comprising a second opening, the second surface located parallel to the first surface. A channel is perpendicular to the housing axis and connects the first opening to the second opening. The channel comprises at least one sidewall. An envelope is fluidly separated from the channel by the at least one sidewall, the envelope at least partially surrounds the channel, and the envelope extends from the first surface to the second surface. The envelope comprises a third opening and at least one second sidewall. A noise-reducing material located on the housing.

Abstract: Medical devices and methods for making and using medical devices are disclosed. A method of mapping electrical activity of a heart may comprise sensing a plurality of signals with a plurality of electrodes positioned within the heart. The method may further comprise separating the plurality of signals into a first group of signals and a second group of signals, and generating a data set that includes at least one known data point and one or more unknown data points. In some examples, the at least one known data point is generated based on the first group of signals.

Abstract: Spinal pedicle screws are placed into vertebrae from the same approach and the same anterior, anterolateral or anterior/lateral exposure that is used for an anterior/lateral spine operation, during the same surgical procedure as the spine operation. Once the anterior spine operation is complete, pedicle screws are placed into the vertebrae with a front-to-back trajectory, in a generally anterior, lateral, anterolateral, or contralateral trajectory, avoiding the need for a second operation exposing the posterior spine.