Patents by Inventor Sean M. Stucke
Sean M. Stucke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230285641Abstract: Embodiments herein relate to thromboresistant coatings, coated devices, and related methods. In an embodiment, a thromboresistant implantable, partially implantable, or wearable medical device is included having a substrate, a non-fouling basecoat layer, and a lubricious topcoat layer. The non-fouling basecoat layer can include a hydrophilic component and a hydrophobic component. The non-fouling basecoat layer is disposed over the substrate. The lubricious topcoat layer can include a photo-reactive polyvinylpyrrolidone compound and a cross-linking agent. The lubricious topcoat layer can be disposed over the non-fouling basecoat layer. Other embodiments are also included herein.Type: ApplicationFiled: March 9, 2023Publication date: September 14, 2023Inventors: Koren Fitzmorris, Syed Hossainy, Sean M. Stucke, Michael Militello, Toni M. Heyer
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Publication number: 20140200411Abstract: Disclosed herein are activatable conductive compositions and methods of making and using activatable conductive compositions. In particular, activatable conductive monomers polymers are described and electrically conductive coatings that include activatable conductive polymers.Type: ApplicationFiled: January 10, 2014Publication date: July 17, 2014Applicant: SurModics, Inc.Inventors: Bruce M. Jelle, Aleksey V. Kurdyumov, Joseph Schmidt McGonigle, Robert W. Hergenrother, Nathan A. Lockwood, Joseph Ventura, Sean M. Stucke
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Patent number: 8535700Abstract: Pro-fibrotic coatings for medical articles are described that include a pro-fibrotic polymer such as collagen. The pro-fibrotic coatings can also include a thromboresistant polymer. The coatings can be formed by activation of photoreactive groups pendent or independent of the coating materials.Type: GrantFiled: October 28, 2005Date of Patent: September 17, 2013Assignee: Surmodics, Inc.Inventors: Joseph A. Chinn, Stephen J. Chudzik, Sean M. Stucke
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Patent number: 8377461Abstract: The invention provides medical articles that include more than one biocompatibility-promoting function. In one aspect, the invention provides a medical articles that include a polymeric matrix including more than one biocompatible agent, wherein each biocompatible agent is provided at a distinct portion of the medical article surface. Methods of making medical articles, as well as methods of using the same, are also described.Type: GrantFiled: December 6, 2005Date of Patent: February 19, 2013Assignee: Surmodics, Inc.Inventors: Joseph A. Chinn, Sean M. Stucke, Stephen J. Chudzik
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Patent number: 8318263Abstract: Described herein is a method for coating an object with a polymer layer. The method includes contacting the object with a first solution comprising a non-polymeric grafting initiator comprising at least one photoinitiator group capable of generating a free radical active species upon absorption of electromagnetic energy, wherein the photoinitiator group is selected from the group consisting of an initiator that is insoluble in polar solvent; and a negatively charged initiator; irradiating the first solution and the object, resulting in the grafting initiator binding to the object; removing the first solution; contacting the object with a second solution comprising a polymerizable monomer having at least one free-radical polymerizable group; and irradiating the second solution and the object, wherein the non-polymeric grafting initiator acts as a photoinitiator for a free-radical polymerization reaction.Type: GrantFiled: December 29, 2010Date of Patent: November 27, 2012Assignee: SurModics, Inc.Inventors: Mark F. Carlson, Steven J. Porter, Sean M. Stucke, Ralph A. Chappa
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Publication number: 20120004339Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.Type: ApplicationFiled: September 16, 2011Publication date: January 5, 2012Applicant: SURMODICS, INC.Inventors: Ralph A. Chappa, Sean M. Stucke, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Dale G. Swan, Peter H. Duquette
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Patent number: 8039524Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.Type: GrantFiled: May 20, 2010Date of Patent: October 18, 2011Assignee: SurModics, Inc.Inventors: Ralph A. Chappa, Sean M. Stucke, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Pam Read, legal representative, Dale G. Swan, Peter H. Duquette
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Publication number: 20110104392Abstract: This invention provides a coating apparatus and methods for coating a device, such as an industrially or medically applicable device. The apparatus is suitable for providing a coating using a photoactivatable compound and a polymerizable compound. In another aspect, the apparatus and methods are useful for coating a device wherein the surface of the device has small pores or apertures. The apparatus includes of containers suitable for holding the object to be coated and the coating solution, a gas supply source for supplying gas to solution, an irradiation station for providing light used in the coating process, and a conveyor mechanism to direct the containers to and from the irradiation station.Type: ApplicationFiled: December 29, 2010Publication date: May 5, 2011Applicant: SurModics, Inc.Inventors: Mark F. Carlson, Steven J. Porter, Sean M. Stucke, Ralph A. Chappa
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Patent number: 7883749Abstract: A method for coating a device, such as an industrially or medically applicable device, with a polymer layer is provided. The method includes contacting the device with a grafting initiator comprising at least one photoinitiator group, exposing the device to radiation, contacting the device with a polymerizable monomer, and again exposing the device to radiation.Type: GrantFiled: March 14, 2006Date of Patent: February 8, 2011Assignee: Surmodics, Inc.Inventors: Mark F. Carlson, Steven J. Porter, Sean M. Stucke, Ralph A. Chappa
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Publication number: 20100240789Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.Type: ApplicationFiled: May 20, 2010Publication date: September 23, 2010Applicant: SurModics, Inc.Inventors: Ralph A. Chappa, Sean M. Stucke, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Dale G. Swan, Peter H. Duquette
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Patent number: 7736689Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.Type: GrantFiled: August 29, 2007Date of Patent: June 15, 2010Assignee: Surmodics, Inc.Inventors: Ralph A. Chappa, Sean M. Stucke, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Dale G. Swan, Peter H. Duquette
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Publication number: 20090176030Abstract: A method for coating a device, such as an industrially or medically applicable device, with a polymer layer is provided. The method includes contacting the device with a grafting initiator comprising at least one photoinitiator group, exposing the device to radiation, contacting the device with a polymerizable monomer, and again exposing the device to radiation.Type: ApplicationFiled: March 14, 2006Publication date: July 9, 2009Inventors: Mark F. Carlson, Steven J. Porter, Sean M. Stucke, Ralph A. Chappa
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Patent number: 7550444Abstract: The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity. In some aspects, the biocompatible coatings of the invention are able to release a bioactive agent. The coatings can be formed using biostable or biodegradable polymeric material and photoreactive groups. The invention also provides methods for improving the quality of bioactive agent-containing coatings by performing pre-irradiation of biocompatible coating compositions.Type: GrantFiled: March 25, 2005Date of Patent: June 23, 2009Assignee: SurModics, Inc.Inventors: Sean M. Stucke, Ralph A. Chappa, Joseph A. Chinn, Aron B. Anderson
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Patent number: 7550443Abstract: The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity that are able to release a bioactive agent, wherein the coatings are formed using biostable or biodegradable polymeric material and photoreactive groups.Type: GrantFiled: March 25, 2005Date of Patent: June 23, 2009Assignee: SurModics, Inc.Inventors: Sean M. Stucke, Ralph A. Chappa, Joseph A. Chinn
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Patent number: 7348055Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.Type: GrantFiled: December 21, 2001Date of Patent: March 25, 2008Assignee: SurModics, Inc.Inventors: Ralph A. Chappa, Sean M. Stucke, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Dale G. Swan, Peter H. Duquette
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Publication number: 20080063627Abstract: The invention provides implantable tissue graft materials composed of a collagenous tissue scaffold and a biocompatible agent bonded to the tissue scaffold via an activated photoreactive group. The invention further provides methods including steps of obtaining a tissue graft material comprising a collagenous tissue scaffold; contacting the collagenous tissue scaffold with a biocompatible agent composition that includes biocompatible agent and one or more photoreactive groups; and treating the collagenous tissue scaffold and biocompatible agent composition to activate the photoreactive groups and bond the biocompatible agent to the tissue scaffold via one or more activated photoreactive groups. Implantable prostheses formed of the tissue graft material are also contemplated.Type: ApplicationFiled: September 12, 2006Publication date: March 13, 2008Inventors: Sean M. Stucke, Toni Michelle Heyer
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Patent number: 7087658Abstract: A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to the surface, as well as photoreactive groups adapted to remain unattached to the surface, and thus serve as photoinitiators for the activation of polymerizable compounds in order to form a polymer layer thereon. Also provided are coating agents, per se, as well as a method of using such agents and the resultant surfaces and devices fabricated therefrom.Type: GrantFiled: December 23, 2003Date of Patent: August 8, 2006Assignee: SurModics, Inc.Inventors: Dale G. Swan, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Ralph A. Chappa, Sean M. Stucke, Peter H. Duquette
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Patent number: 7041174Abstract: This invention provides a coating apparatus and methods for coating a device, such as an industrially or medically applicable device. The apparatus is suitable for providing a coating using a photoactivatable compound and a polymerizable compound. In another aspect, the apparatus and methods are useful for coating a device wherein the surface of the device has small pores or apertures. The apparatus includes of containers suitable for holding the object to be coated and the coating solution, a gas supply source for supplying gas to solution, an irradiation station for providing light used in the coating process, and a conveyor mechanism to direct the containers to and from the irradiation station.Type: GrantFiled: February 19, 2003Date of Patent: May 9, 2006Assignee: SunModics,Inc.Inventors: Mark F. Carlson, Steven J. Porter, Sean M. Stucke, Ralph A. Chappa
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Publication number: 20040161547Abstract: This invention provides a coating apparatus and methods for coating a device, such as an industrially or medically applicable device. The apparatus is suitable for providing a coating using a photoactivatable compound and a polymerizable compound. In another aspect, the apparatus and methods are useful for coating a device wherein the surface of the device has small pores or apertures. The apparatus includes of containers suitable for holding the object to be coated and the coating solution, a gas supply source for supplying gas to solution, an irradiation station for providing light used in the coating process, and a conveyor mechanism to direct the containers to and from the irradiation station.Type: ApplicationFiled: February 19, 2003Publication date: August 19, 2004Applicant: SurModics, Inc.Inventors: Mark F. Carlson, Steven J. Porter, Sean M. Stucke, Ralph A. Chappa
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Publication number: 20040137164Abstract: A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to the surface, as well as photoreactive groups adapted to remain unattached to the surface, and thus serve as photoinitiators for the activation of polymerizable compounds in order to form a polymer layer thereon. Also provided are coating agents, per se, as well as a method of using such agents and the resultant surfaces and devices fabricated therefrom.Type: ApplicationFiled: December 23, 2003Publication date: July 15, 2004Applicant: SURMODICS, INC.Inventors: Dale G. Swan, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Ralph A. Chappa, Sean M. Stucke, Peter H. Duquette