Patents by Inventor Seang H. Yiv

Seang H. Yiv has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020111360
    Abstract: Pharmaceutical compositions for parenteral administration of poorly soluble quinazoline compounds in the form of microemulsions or micellar solutions are described. The compositions are useful in treating patients suffering from cancer or having allergic reactions.
    Type: Application
    Filed: September 19, 2001
    Publication date: August 15, 2002
    Applicant: PARKER HUGHES INSTITUTE
    Inventors: Seang H. Yiv, Mingshu Li, Fatih M. Uckun
  • Patent number: 6245349
    Abstract: The present invention provides drug delivery compositions in both concentrated and diluted forms for use as vehicles in the administration of various active agents. The drug delivery compositions are primarily designed for use with lipophilic, amphipathic, and sparingly water soluble active agents, preferably drugs. The drug delivery compositions are to be administered to an animal to effect uptake of the active agent. The primary mode of administration is by intravenous, intra-arterial, intrathecal, intraperitoneal, intraocular, intra-articular, intramuscular or subcutaneous injection. The concentrated drug delivery compositions are formulated with a phospholipid component, a component selected from propylene glycol or certain polyethylene glycol compounds, a high HLB surfactant, and the drug component, with water and/or an oil component optional. The concentrated drug delivery compositions can be diluted with an aqueous fluid to form an oil-in-water microemulsion composition.
    Type: Grant
    Filed: February 23, 1996
    Date of Patent: June 12, 2001
    Assignee: √Član Corporation plc
    Inventors: Seang H. Yiv, Alex K. Tustian
  • Patent number: 5707648
    Abstract: There is provided a stable transparent multi-component composition useful for the delivery of water soluble active agents to animals. The compositions are formulated with a mixture of an oil phase, an aqueous phase, and a surfactant system, along with the active agent to be delivered to the animal. The compositions are specially formulated to be compatible with capsules such as gelatin and starch capsules. The aqueous phase of the compositions contains a substantial amount of polyethylene glycol and can optionally also contain a plasticizer. Preferred active agents are proteinaceous materials.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: January 13, 1998
    Assignee: LDS Technologies, Inc.
    Inventor: Seang H. Yiv
  • Patent number: 5688761
    Abstract: There is provided a water-in-oil (w/o) micro emulsion which readily converts to an oil-in-water (o/w) emulsion by the addition of aqueous fluid to the w/o microemulsion, whereby an water-soluble biologically-active material in the aqueous phase is released for absorption by the body. The w/o microemulsion contains a preferred high purity short chain monoglyceride surfactant. The w/o microemulsion is particularly useful for storing proteins and the like for ling periods of time at room temperature and above until they are ready for use, at which time the addition of aqueous fluid converts the microemulsion to an o/w emulsion and release the protein.
    Type: Grant
    Filed: June 8, 1995
    Date of Patent: November 18, 1997
    Assignee: LDS Technologies, Inc.
    Inventors: Albert J. Owen, Seang H. Yiv, Ani B. Sarkahian
  • Patent number: 5646109
    Abstract: There is provided a water-in-oil (w/o) microemulsion which readily converts to an oil-in-water (o/w) emulsion by the addition of aqueous fluid to the w/o microemulsion, whereby any water-soluble biologically-active material in the aqueous phase is released for absorption by the body. The w/o microemulsion is particularly useful for storing proteins and the like for long periods of time at room temperature and above until they are ready for use, at which time the addition of aqueous fluid converts the microemulsion to an o/w emulsion and releases the protein.
    Type: Grant
    Filed: April 20, 1995
    Date of Patent: July 8, 1997
    Assignee: LDS Technologies, Inc.
    Inventors: Albert J. Owen, Seang H. Yiv
  • Patent number: 5633226
    Abstract: There is provided a water-in-oil (w/o) microemulsion which readily converts to an oil-in-water (o/w) emulsion by the addition of aqueous fluid to the w/o microemulsion, whereby any water-soluble biologically-active material in the aqueous phase is released for absorption by the body. The w/o microemulsion is particularly useful for storing proteins and the like for long periods of time at room temperature and above until they are ready for use, at which time the addition of aqueous fluid converts the microemulsion to an o/w emulsion and releases the protein.
    Type: Grant
    Filed: April 20, 1995
    Date of Patent: May 27, 1997
    Assignee: LDS Technologies, Inc.
    Inventors: Albert J. Owen, Seang H. Yiv
  • Patent number: 5444041
    Abstract: There is provided a water-in-oil (w/o) microemulsion which readily converts to an oil-in-water (o/w) emulsion by the addition of aqueous fluid to the w/o microemulsion, whereby any water-soluble biologically-active material in the aqueous phase is released for absorption by the body. The w/o microemulsion is particularly useful for storing proteins and the like for long periods of time at room temperature and above until they are ready for use, at which time the addition of aqueous fluid converts the microemulsion to an o/w emulsion and releases the protein.
    Type: Grant
    Filed: May 20, 1992
    Date of Patent: August 22, 1995
    Assignee: Ibah, Inc.
    Inventors: Albert J. Owen, Seang H. Yiv, Ani B. Sarkahian
  • Patent number: 4975468
    Abstract: A fluorocarbon microemulsion is provided which contains an ethoxylated alcohol as surfactant, the alcohol containing a tertiary carbon atom.
    Type: Grant
    Filed: April 3, 1989
    Date of Patent: December 4, 1990
    Assignee: Affinity Biotech, Inc.
    Inventor: Seang H. Yiv