Patents by Inventor Seiji Ishizeki

Seiji Ishizeki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4849512
    Abstract: Derivatives of 3-acylamino-3-deoxyallose represented by the following formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 may be hydrogen atoms, or R.sup.1 and R.sup.2, and R.sup.3 and R.sup.4 may be in combination an isopropylidene group, R.sup.5 represents a hydrogen atom or alkyl group, and R.sup.6 represents a hydrogen atom or acyl group, are disclosed. One of the typical compound 3-deoxy-3-(3-tetradecanoyloxytetradecanoylamino)-1,2:5,6-di-O-isopropylide ne- .alpha.-D-allofuranose is prepared by reacting 3-tetradecanoyloxytetradecanoic acid and 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-.alpha.-D-allofuranose in the presence of N,N'-dicyclohexylcarbodiimide, as a dehydrating agent. The compound has an excellent carcinostatic activity.
    Type: Grant
    Filed: April 1, 1988
    Date of Patent: July 18, 1989
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Minoru Tokizawa, Mari Otsuka, Kazuhiko Irinoda, Seiji Ishizeki, Fumio Ishii, Kenichi Kukita, Hideaki Matsuda, Tatsuhiko Katori
  • Patent number: 4584377
    Abstract: Disclosed herein are Fredericamycin A derivatives, each, represented by the following general formula (I): ##STR1## wherein R means a hydrogen atom or acyl group, A denotes ##STR2## and dotted bonds are optional, with a proviso that when A is ##STR3## or the dotted bonds are contained, R is other than hydrogen atom. They have excellent antibacterial and antitumor activities and at the same time, are extremely stable compared with Fredericamycin A.
    Type: Grant
    Filed: August 9, 1984
    Date of Patent: April 22, 1986
    Assignee: SS Pharmaceutical Co., Ltd.
    Inventors: Koichi Yokoi, Hiroshi Hasegawa, Tadashi Narita, Takemitsu Asaoka, Kenichi Kukita, Seiji Ishizeki, Toshiaki Nakashima