Patents by Inventor Seiki WAKUI

Seiki WAKUI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220373551
    Abstract: A method for separation and detection of exosomes may include: bringing a biological sample into contact with a capture molecule, the capture molecule including a specific binding substance for an antigen expressed on a cancer cell surface, to form a complex of an exosome and the capture molecule; and a bringing the complex into contact with a detector molecule, the detector molecule including a specific binding substance for an antigen expressed on a cancer cell surface and a labeling substance, to detect the complex by using the detector molecule, in which the antigen expressed on a cancer cell surface for at least one of the capture molecule and the detector molecule is cell-surface vimentin.
    Type: Application
    Filed: October 2, 2020
    Publication date: November 24, 2022
    Applicants: JSR Corporation, KEIO UNIVERSITY
    Inventors: Seiki WAKUI, Yutaka KAWAKAMI, Tomonori YAGUCHI
  • Publication number: 20200376029
    Abstract: A medicament for cancer treatment includes as an active ingredient T cells having a chimeric antigen receptor that binds to glypican 1 (GPC1). The medicament is administered concomitantly with an immune checkpoint inhibitor according to regimens (a) and (b) to maintain the anti-tumor activity of the T cells: The regimens include (a) administering an effective amount of the T cells to a cancer patient and (b) continuously administering 0.01 mg/kg body weight to 100 mg/kg body weight of the immune checkpoint inhibitor per dose to the cancer patient every 1 to 5 weeks.
    Type: Application
    Filed: May 14, 2020
    Publication date: December 3, 2020
    Inventors: Daiki Kato, Tomonori Yaguchi, Yutaka Kawakami, Seiki Wakui, Toru Shoji, Ayuko Matsui
  • Patent number: 10451627
    Abstract: The present invention relates to a method for assaying soluble GPC3 protein in a test sample, comprising using two different antibodies binding to different epitopes present in the N-terminal region of GPC3 protein.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 22, 2019
    Assignees: CHUGAI SEIYAKU KABUSHIKI KAISHA, JSR CORPORATION, JSR LIFE SCIENCES CORPORATION
    Inventors: Toshihiko Ohtomo, Jun Amano, Hideki Adachi, Tsukasa Suzuki, Motoaki Mizuuchi, Tetsuji Yamaguchi, Seiki Wakui
  • Publication number: 20170010270
    Abstract: The present invention relates to a method for assaying soluble GPC3 protein in a test sample, comprising using two different antibodies binding to different epitopes present in the N-terminal region of GPC3 protein.
    Type: Application
    Filed: June 25, 2014
    Publication date: January 12, 2017
    Applicants: CHUGAI SEIYAKU KABUSHIKI KAISHA, JSR CORPORATION, JSR LIFE SCIENCES CORPORATION
    Inventors: Toshihiko OHTOMO, Jun AMANO, Hideki ADACHI, Tsukasa SUZUKI, Motoaki MIZUUCHI, Tetsuji YAMAGUCHI, Seiki WAKUI