Patents by Inventor Sergio Landau
Sergio Landau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20040074076Abstract: A method of manufacture for a drug cartridge assembly. The method includes providing a drug cartridge, providing a nozzle sub-assembly, and sterilizing the drug cartridge and nozzle sub-assembly. The method further includes assembling the drug cartridge and nozzle sub-assembly together in a configuration that enables ejection of liquid out of the drug cartridge through the nozzle sub-assembly. The method further includes filling the drug cartridge with a liquid, such as an injectable drug. The method may include separate sterilization of the drug cartridge and nozzle sub-assembly, using different sterilization processes. Portions of the method may be performed prior to sterilization within a first cleanroom, with subsequent steps being performed in a second cleanroom having a substantially lower particulate-per-volume rating than the first cleanroom.Type: ApplicationFiled: October 16, 2002Publication date: April 22, 2004Applicant: Bioject Inc.Inventor: Sergio Landau
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Patent number: 6689093Abstract: A gas-powered, single-use, needle-less hypodermic jet injection device (10, 210, 410) includes a hand-held injector (12, 212, 412), and a drug injection cartridge (14, 114, 414) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (82, 182, 482) which remains sealed until the moment of injection and powers the jet injection after opening of this cartridge.Type: GrantFiled: February 5, 2001Date of Patent: February 10, 2004Assignee: Bioject, Inc.Inventor: Sergio Landau
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Patent number: 6676630Abstract: A needle-free injection device. The injection device includes a user-grippable housing and a syringe assembly movably secured to the housing. The syringe assembly is configured to expel injectable fluid out of a nozzle upon application of pressurized gas to the syringe assembly. The injection device also includes a pressurized gas delivery mechanism disposed within the housing and configured to selectively apply pressurized gas to the syringe assembly. The pressurized gas delivery mechanism is at least partly actuated by pressing the nozzle onto an injection site so that the syringe assembly moves relative to the housing.Type: GrantFiled: June 4, 2002Date of Patent: January 13, 2004Assignee: Bioject Medical Technologies, Inc.Inventors: Sergio Landau, Dan Williamson, John R. Marshall
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Publication number: 20030225368Abstract: A needle-free injection device. The injection device includes a user-grippable housing and a syringe assembly movably secured to the housing. The syringe assembly is configured to expel injectable fluid out of a nozzle upon application of pressurized gas to the syringe assembly. The injection device also includes a pressurized gas delivery mechanism disposed within the housing and configured to selectively apply pressurized gas to the syringe assembly. The pressurized gas delivery mechanism is at least partly actuated by pressing the nozzle onto an injection site so that the syringe assembly moves relative to the housing.Type: ApplicationFiled: June 4, 2002Publication date: December 4, 2003Applicant: Bioject Inc.Inventors: Sergio Landau, Dan Williamson, John R. Marshall
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Patent number: 6648850Abstract: A gas-powered, durable, needle-less hypodermic jet injection device (10, 110) includes a hand-held injector (12, 112) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (28) which is opened in preparation to effecting a jet injection, and which powers the jet injection, but from which pressurized gas is not allowed to flow in volume until a user of the device shifts a valving spool (24).Type: GrantFiled: June 8, 2001Date of Patent: November 18, 2003Assignee: Bioject, Inc.Inventor: Sergio Landau
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Patent number: 6645170Abstract: One form of the present invention provides a needle-free injection system including the following components: a cartridge for holding liquid drug prior to injection, the cartridge having a rear end and a front end; a plug mounted to the front end of the cartridge, the plug including a channel; a displaceable valve positioned within the channel prior to injection; and a nozzle portion for receiving liquid drug from the glass cartridge for injection, the nozzle portion including an injection orifice and a drug chamber having a valve seat designed to receive the valve to facilitate injection of liquid drug through the injection orifice.Type: GrantFiled: May 23, 2001Date of Patent: November 11, 2003Assignee: Bioject Medical Technologies, Inc.Inventor: Sergio Landau
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Patent number: 6641554Abstract: One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being aligned with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a portion of dried drug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.Type: GrantFiled: October 29, 2002Date of Patent: November 4, 2003Assignee: Bioject Medical Technologies, Inc.Inventor: Sergio Landau
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Patent number: 6607510Abstract: In accordance with the current invention, a needle-free injection system includes a cap that has a first seal for sealing an injection orifice when the cap is engaged with an injection end of the system. The cap also includes a push-rod for facilitating priming of the system when engaged with a priming end of the system. The system also includes a push-rod engaging mechanism disposed at the priming end of the system for receiving the push-rod for priming the system. The system further includes a gas cylinder for supplying pressurized gas for injecting, via the injection orifice, an injectate initially disposed within a storage chamber, and a sealing system for preventing the pressurized gas from ejecting the injectate from the system prior to actuation of the system. Actuation of the system is achieved via a slidable trigger plate.Type: GrantFiled: November 9, 2001Date of Patent: August 19, 2003Assignee: Bioject Medical Technologies Inc.Inventor: Sergio Landau
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Patent number: 6585685Abstract: A gas-powered, durable, needle-free hypodermic jet injection device includes a hand-held injector which carries a disposable injection cartridge with a volume of liquid medication to be injected in the form of a high velocity jet capable of penetrating the skin without the use of a hypodermic needle. The injection device provides an injection orifice, and an injection piston. Forceful movement of the injection piston caused by high pressure gas causes a high velocity injection jet of liquid medication to be expelled from the injection cylinder via the injection orifice. The injection device includes features which improve its safety, and also which improve its ease of manufacture, its durability, and its cost effectiveness.Type: GrantFiled: May 9, 2002Date of Patent: July 1, 2003Assignee: Bioject Inc.Inventors: John Lawrence Staylor, Sergio Landau, Daniel E. Williamson
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Patent number: 6572581Abstract: A gas-powered, single-use, needle-less jet injection device (10, 210, 410) includes a hand-held injector (12, 212, 412), and a drug injection cartridge (14, 114, 414) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (82, 182, 382) which remains sealed until the moment of injection and powers the jet injection after opening of this cartridge.Type: GrantFiled: June 5, 2000Date of Patent: June 3, 2003Assignee: Bioject Inc.Inventor: Sergio Landau
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Publication number: 20030093030Abstract: In accordance with the current invention, a needle-free injection system includes a cap that has a first seal for sealing an injection orifice when the cap is engaged with an injection end of the system. The cap also includes a push-rod for facilitating priming of the system when engaged with a priming end of the system. The system also includes a push-rod engaging mechanism disposed at the priming end of the system for receiving the push-rod for priming the system. The system further includes a gas cylinder for supplying pressurized gas for injecting, via the injection orifice, an injectate initially disposed within a storage chamber, and a sealing system for preventing the pressurized gas from ejecting the injectate from the system prior to actuation of the system. Actuation of the system is achieved via a slidable trigger plate.Type: ApplicationFiled: November 9, 2001Publication date: May 15, 2003Applicant: Bioject Medical Technologies Inc.Inventor: Sergio Landau
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Publication number: 20030065286Abstract: One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being aligned with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a portion of dried drug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.Type: ApplicationFiled: October 29, 2002Publication date: April 3, 2003Applicant: Bioject Medical Technologies Inc.Inventor: Sergio Landau
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Patent number: 6506177Abstract: A needle-less hypodermic jet injection system includes a hand-held injector, and an energizing or cocking unit for use with the injector to prepare it for administering an injection. The hand-held unit includes a cartridge which provides a cylinder of liquid medication to be injected, an injection orifice, and an injection piston forceful movement of which causes an injection jet of medication to be expelled from the orifice. A power unit of the injector provides for forceful movement of the injection piston when a trigger is actuated. After being used to effect an injection, the injector is interfaced with an energizer unit which cocks the power unit preparatory to the next injection.Type: GrantFiled: October 14, 1998Date of Patent: January 14, 2003Inventor: Sergio Landau
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Publication number: 20020188251Abstract: A gas-powered, durable, needle-free hypodermic jet injection device includes a hand-held injector which carries a disposable injection cartridge with a volume of liquid medication to be injected in the form of a high velocity jet capable of penetrating the skin without the use of a hypodermic needle. The injection device provides an injection orifice, and an injection piston. Forceful movement of the injection piston caused by high pressure gas causes a high velocity injection jet of liquid medication to be expelled from the injection cylinder via the injection orifice. The injection device includes features which improve its safety, and also which improve its ease of manufacture, its durability, and its cost effectiveness.Type: ApplicationFiled: May 9, 2002Publication date: December 12, 2002Applicant: Bioject, Inc.Inventors: John Lawrence Staylor, Sergio Landau, Daniel E. Williamson
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Publication number: 20020188249Abstract: A gas-powered, durable, needle-less hypodermic jet injection device (10, 110) includes a hand-held injector (12, 112) which provides a volume of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure cartridge (28) which is opened in preparation to effecting a jet injection, and which powers the jet injection, but from which pressurized gas is not allowed to flow in volume until a user of the device shifts a valving spool (24).Type: ApplicationFiled: June 8, 2001Publication date: December 12, 2002Inventor: Sergio Landau
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Publication number: 20020188250Abstract: A gas-powered, durable, needle-less hypodermic jet injection device (10, 210) includes a hand-held injector (12, 212) which receives into an injection cylinder a volume of liquid medication to be injected in the form of a high velocity jet capable of penetrating the skin without the use of a hypodermic needle. The injection device provides an injection orifice, and an injection piston. Forceful movement of the injection piston causes a high velocity injection jet of liquid medication to be expelled from the injection cylinder via the injection orifice. The injection device includes features which improve its usability, particularly for users with hands that are possibly weak, feeble, or arthritic, for example; and also includes additional features which improve manufacturability, durability, and cost effectiveness of the device.Type: ApplicationFiled: January 25, 2002Publication date: December 12, 2002Inventors: Sergio Landau, Daniel Williamson
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Patent number: 6471669Abstract: One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being coaxial with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a drug plug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.Type: GrantFiled: March 5, 2001Date of Patent: October 29, 2002Assignee: Bioject Medical Technologies Inc.Inventor: Sergio Landau
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Publication number: 20020151839Abstract: A needle-less hypodermic jet injection system includes a hand-held injector, and an energizing or cocking unit for use with the injector to prepare it for administering an injection. The hand-held unit includes a cartridge which provides a cylinder of liquid medication to be injected, an injection orifice, and an injection piston forceful movement of which causes an injection jet of medication to be expelled from the orifice. A power unit of the injector provides for forceful movement of the injection piston when a trigger is actuated. After being used to effect an injection, the injector is interfaced with an energizer unit which cocks the power unit preparatory to the next injection.Type: ApplicationFiled: October 14, 1998Publication date: October 17, 2002Inventor: SERGIO LANDAU
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Publication number: 20020123717Abstract: One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being coaxial with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a drug plug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.Type: ApplicationFiled: March 5, 2001Publication date: September 5, 2002Applicant: Bioject Medical Technologies Inc.Inventor: Sergio Landau
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Publication number: 20020123718Abstract: One form of the present invention provides a needle-free injection system including the following components: a cartridge for holding liquid drug prior to injection, the cartridge having a rear end and a front end; a plug mounted to the front end of the cartridge, the plug including a channel; a displaceable valve positioned within the channel prior to injection; and a nozzle portion for receiving liquid drug from the glass cartridge for injection, the nozzle portion including an injection orifice and a drug chamber having a valve seat designed to receive the valve to facilitate injection of liquid drug through the injection orifice.Type: ApplicationFiled: May 23, 2001Publication date: September 5, 2002Inventor: Sergio Landau