Patents by Inventor Sergio Roman-Roman

Sergio Roman-Roman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide sequence coding for variable regions of ? chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Patent number: 8709426
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of ? chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: April 29, 2014
    Assignee: Aventis Pharma S.A.
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • NUCLEOTIDE SEQUENCE CODING FOR VARIABLE REGIONS OF BETA CHAINS OF HUMAN T LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDE SEGMENTS AND THE DIAGNOSTIC AND THERAPEUTIC USES
    Publication number: 20080069770
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of ? chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Application
    Filed: October 5, 2007
    Publication date: March 20, 2008
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Thierry HERCEND, Frederic TRIEBEL, Sergio ROMAN-ROMAN, Laurent FERRADINI
  • Nucleotide sequences coding for variable regions of ? chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Patent number: 7294712
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of ? chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Grant
    Filed: March 12, 2002
    Date of Patent: November 13, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Genes involved in osteogenesis, and methods of use
    Publication number: 20060030541
    Abstract: The present invention relates to methods of diagnosis, therapy, and screening of new therapeutic compounds in the field of osteogenesis, based on the differential expression observed for the genes of the invention, represented by SEQ ID No 2, 7, 22, 25, 33, 35, 37, 38, 42, 47, 64, 69 or 77, 82, 97, 100, 108, 110, 112, 113, 117, 122, 139, 151, 158, 160, 172, 182, 184, 187, 188, 194.
    Type: Application
    Filed: October 7, 2005
    Publication date: February 9, 2006
    Applicant: Proskelia
    Inventors: Teresa Garcia, Sergio Roman Roman, Roland Baron, Katherine Call, Joachim Theilhaber, Timothy Connolly, Amanda Jackson, Steven Bushnell, Georges Rawadi
  • Genes involved in osteogenesis, and methods of use
    Publication number: 20040265808
    Abstract: The present invention relates to methods of diagnosis, therapy, and screening of new therapeutic compounds in the field of osteogenesis, based on the differential expression observed for the genes of the invention, represented by SEQ ID No 1 to SEQ ID No 150, or SEQ ID No 151, 152 or 153, or SEQ ID No 154 to SEQ ID No 196, or SEQ ID No 197 to SEQ ID No 210, or SEQ ID No 211 to SEQ ID No 229, or SEQ ID No 230 to SEQ ID No 234, or SEQ ID No 235 to SEQ ID No 245.
    Type: Application
    Filed: May 3, 2004
    Publication date: December 30, 2004
    Inventors: Teresa Garcia, Sergio Roman Roman, Roland Baron, Katherine Call, Joachim Theilhaber, Timothy Connolly, Amanda Jackson, Steven E Bushnell, Georges Rawadi
  • Nucleotide sequences coding for variable regions of the alpha chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Patent number: 6596536
    Abstract: An isolated antibody that specifically binds a peptide coded by a nucleotide sequence coding for a variable region of &agr; chain of an human T lymphocyte receptor, said nucleotide sequence having a nucleotide sequence chosen from any of: V&agr; segments having any one of the sequences SEQ ID Nos. 1 to 11 or J&agr; segments having one of the sequence SEQ ID Nos. 13 or 15 to 19 and hybridomas producing said antibodies.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: July 22, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Nucleotide sequences coding for variable regions of beta chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Publication number: 20030068628
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of &bgr; chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Application
    Filed: March 12, 2002
    Publication date: April 10, 2003
    Applicant: Aventis Pharma S.A.
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Regulator gene and system useful for the diagnosis and therapy of osteoporosis
    Publication number: 20030027151
    Abstract: A bone strength and mineralization regulatory (“BSMR”) protein is provided that can exist in multiple forms and that affects bone density. Polymorphic gene sequences of the protein are provided that are diagnostic of predipostion to osteoporosis. Other detection tools, compositions and methods of their use also are provided for predicting, evaluating and altering bone strength and mineralization status. The invention provides new natural and synthetic pharmaceuticals that effect the BSMR regulatory pathway and improve bone status. Tools also are provided for finding new pharmaceuticals that operate by binding to BSMR and that activate and/or deactivate this protein's biological function related to osteoporosis and blood vessel formation.
    Type: Application
    Filed: August 17, 2001
    Publication date: February 6, 2003
    Inventors: Matthew L. Warman, Yaoqin Gong, Bjorn R. Olsen, Georges Rawadi, Sergio Roman-Roman
  • Nucleotide sequences coding for variable regions of the .alpha.chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic muses
    Patent number: 6114516
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of the .alpha. chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: September 5, 2000
    Assignee: Hoechst Marion Roussel
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Isolated V.beta. TCR antibodies
    Patent number: 5830758
    Abstract: An isolated antibody that specifically binds a peptide coded by a nucleotide sequence coding for a variable region of .beta.-chain of an human T lymphocyte receptor, said nucleotide sequence having a nucleotide sequence selected from any of:the nucleotide sequences of SEQ ID Nos. 2 to 19.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: November 3, 1998
    Assignee: Roussel Uclaf
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Nucleotide sequence coding for variable regions of the .alpha. chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Patent number: 5817511
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of the .alpha. chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: October 6, 1998
    Assignee: Roussel Uclaf
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Nucleotide sequences for .alpha. chain variable regions in human lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Patent number: 5798231
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of the .alpha. chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: August 25, 1998
    Assignee: Roussel Uclaf
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
  • Nucleotide sequences coding for variable regions of .beta. chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
    Patent number: 5700907
    Abstract: The present invention relates to new nucleotide sequences coding for variable regions of .beta. chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: December 23, 1997
    Assignee: Roussel Uclaf
    Inventors: Thierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini