Patents by Inventor Sergiu M. Gorun

Sergiu M. Gorun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210277279
    Abstract: Photoactive polymer coatings and methods of making the same are disclosed herein. In some embodiments, a polymer coating having a porous structure extending throughout the polymer coating, wherein the porous structure is present at an exposed surface of the polymer coating creating a roughened surface, wherein the polymer of the polymer coating is a siloxane based polymer; and a modified support particle disposed within the polymer coating, wherein the modified support particle includes a substituted phthalocyanine and a support particle. In some embodiments, the substituted phthalocyanine is a halogenated phthalocyanine.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 9, 2021
    Applicant: Seton Hall University
    Inventors: James E. Hanson, Abdul Azeez, Sergiu M. Gorun
  • Patent number: 11015032
    Abstract: Photoactive polymer coatings and methods of making the same are disclosed herein. In some embodiments, a polymer coating comprises a polymer matrix having a porous structure extending throughout the polymer matrix, wherein the porous structure is present at an exposed surface of the polymer coating creating a roughened surface, and a modified support particle disposed within the polymer matrix, wherein the modified support particle includes a substituted phthalocyanine and a support particle. In some embodiments, the substituted phthalocyanine is a halogenated phthalocyanine.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: May 25, 2021
    Assignee: Seton Hall University
    Inventors: James E. Hanson, Abdul Azeez, Sergiu M. Gorun
  • Patent number: 10942142
    Abstract: Methods and apparatus for detecting an analyte using fluorinated phthalocyanines is disclosed herein. A method for detecting an analyte includes illuminating an analyte solution which contacts an electrode comprising a conductive material having a photosensitizer coupled thereto to generate a reactive oxygen species, wherein the photosensitizer is a fluorinated pthalocyanine having a metal or a non-metal center, oxidizing an analyte present in the analyte solution with the reactive oxygen species to form an oxidized analyte, and detecting a current resulting from the reduction of the oxidized analyte at the electrode.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: March 9, 2021
    Assignees: Seton Hall University
    Inventors: Karolien De Wael, Sergiu M. Gorun, Stanislav Trashin, Erik N. Carrión
  • Publication number: 20190270858
    Abstract: Photoactive polymer coatings and methods of making the same are disclosed herein. In some embodiments, a polymer coating comprises a polymer matrix having a porous structure extending throughout the polymer matrix, wherein the porous structure is present at an exposed surface of the polymer coating creating a roughened surface, and a modified support particle disposed within the polymer matrix, wherein the modified support particle includes a substituted phthalocyanine and a support particle. In some embodiments, the substituted phthalocyanine is a halogenated phthalocyanine.
    Type: Application
    Filed: February 28, 2019
    Publication date: September 5, 2019
    Applicant: Seton Hall University
    Inventors: James E. Hanson, Abdul Azeez, Sergiu M. Gorun
  • Publication number: 20190017955
    Abstract: Methods and apparatus for detecting an analyte using fluorinated phthalocyanines is disclosed herein. A method for detecting an analyte includes illuminating an analyte solution which contacts an electrode comprising a conductive material having a photosensitizer coupled thereto to generate a reactive oxygen species, wherein the photosensitizer is a fluorinated pthalocyanine having a metal or a non-metal center, oxidizing an analyte present in the analyte solution with the reactive oxygen species to form an oxidized analyte, and detecting a current resulting from the reduction of the oxidized analyte at the electrode.
    Type: Application
    Filed: July 13, 2018
    Publication date: January 17, 2019
    Applicants: Seton Hall University, AXES Research Group, Department of Chemistry, University of Antwerp,
    Inventors: Karolien De Wael, Sergiu M. Gorun, Stanislav Trashin, Erik N. Carrión
  • Patent number: 9956549
    Abstract: A new class of organic-inorganic hybrid composite materials, composites of a fluoroalkyl fluorophthalocyanine and a solid-state support containing an imidazole group. The new class of composite materials can be used as a heterogeneous catalyst for the heterogeneous oxidation organic molecules in aqueous and some organic solvents systems is claimed.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: May 1, 2018
    Assignee: Seton Hall University
    Inventors: Hemantbhai Patel, Sergiu M. Gorun
  • Patent number: 9731284
    Abstract: A process for use of composite catalysts for oxidation of amines during synthesis of energetic compounds. This method overcomes the safety concerns associated with dangerous reaction conditions for these energetic materials. The process requires exposing phthalocyanine conjugated to an inorganic substrate to the precursor reactant and activating the composite material to light and oxygen to covert amine groups into oxidized nitrogen species.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: August 15, 2017
    Assignees: The United States of America as Represented by the Secretary of the Army, Seton Hall University
    Inventors: Peggy A. Sanchez, Kimberly Griswold, Sergiu M. Gorun, Hemantbhai H. Patel
  • Patent number: 9572898
    Abstract: Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: February 21, 2017
    Assignee: Seton Hall University
    Inventors: David Sabatino, Sergiu M. Gorun, Emily Borland, Hemantbhai Patel, Pradeepkumar Patel, Erik Nathaniel Carrión
  • Patent number: 9260630
    Abstract: Coating compositions that include a halopigment dispersed within a silicon-containing polymeric matrix (e.g., a polysiloxane polymer) are provided. The halopigment comprises a halogenated phthalocyanine (e.g., a fluorinated phthalocyanine) attached to a support particle (e.g., a metal oxide, a non-metal oxide, and/or an inert material). The halogenated phthalocyanine can have the formula: (16R-Pc)nMLo, where each R is, independently, a halogen or a perhaloalkyl group, with each R group being independent from the other groups; Pc is a phthalocyanine compound; 1?n?2; L is a ligand or ligands and M is a cation; and 0?o?8. Methods are also provided for forming such a coating composition and for coating a substrate with the coating composition.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: February 16, 2016
    Inventors: Sergiu M. Gorun, James Sullivan, Karpagavalli Ramji
  • Publication number: 20150368194
    Abstract: Organo-metallic materials with reduced steric hindrance and the ability to aggregate are disclosed. The metal remains capable of binding additional molecules. As an example, Zn complexes that prove aggregation are provided. Such aggregation may help improve or trigger new surface properties of the materials, alone or in combination with others. In a further implementation of the present disclosure, a robust molecule that resists degradation via nucleophilic, electrophilic and radical attacks is provided. Coordinated O2 is reduced catalytically, producing efficiently thyil radicals in spite of the extreme electronic deficiency of the catalyst.
    Type: Application
    Filed: August 31, 2015
    Publication date: December 24, 2015
    Inventors: Sergiu M. Gorun, Andrei Ioan Loas, Kimberly Griswold, Lukasz Lapok, Hemantbhai Hasmukhbhai Patel, Robert Gerdes
  • Publication number: 20150315137
    Abstract: Organo-metallic materials with reduced steric hindrance and the ability to aggregate are disclosed. The metal remains capable of binding additional molecules. As an example, Zn complexes that prove aggregation are provided. Such aggregation may help improve or trigger new surface properties of the materials, alone or in combination with others. In a further implementation of the present disclosure, a robust molecule that resists degradation via nucleophilic, electrophilic and radical attacks is provided. Coordinated O2 is reduced catalytically, producing efficiently thyil radicals in spite of the extreme electronic deficiency of the catalyst.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 5, 2015
    Applicant: NEW JERSEY INSTITUTE OF TECHNOLOGY
    Inventors: Sergiu M. Gorun, Andrei Ioan Loas, Kimberly Griswold, Lukasz Lapok, Hemantbhai Hasmukhbhai Patel, Robert Gerdes
  • Publication number: 20150284592
    Abstract: Coating compositions that include a halopigment dispersed within a silicon-containing polymeric matrix (e.g., a polysiloxane polymer) are provided. The halopigment comprises a halogenated phthalocyanine (e.g., a fluorinated phthalocyanine) attached to a support particle (e.g., a metal oxide, a non-metal oxide, and/or an inert material). The halogenated phthalocyanine can have the formula: (16R-Pc)nMLo, where each R is, independently, a halogen or a perhaloalkyl group, with each R group being independent from the other groups; Pc is a phthalocyanine compound; 1?n?2; L is a ligand or ligands and M is a cation; and 0?o?8. Methods are also provided for forming such a coating composition and for coating a substrate with the coating composition.
    Type: Application
    Filed: April 2, 2015
    Publication date: October 8, 2015
    Inventors: Sergiu M. Gorun, James Sullivan, Karpagavalli Ramji
  • Patent number: 9150431
    Abstract: A method of purifying or sanitizing contaminated water to be potable, by exposing the water in the presence of light, to an electrically neutral metal complex of a perfluoroalkylated fluorinated phthalocyanine photosensitizer, having only external R groups with C—F bonds, preferably F64PcZn; whereby, a sufficient quantity of singlet oxygen is provided by the chemical reaction of the light and the photosensitizer to destroy the pollutants or pathogens present in the contaminated water.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: October 6, 2015
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Sergiu M. Gorun, Kimberly Ann Griswold
  • Publication number: 20150266011
    Abstract: A new class of hybrid composite materials, composites of a perfluoroalkyl fluoro phthalocyanine and a solid-state support—useful as heterogeneous catalysts for the degradation of organic molecules in aqueous systems via the photocatalytic generation of reactive oxygen species.
    Type: Application
    Filed: March 24, 2014
    Publication date: September 24, 2015
    Inventors: Kimberly A. Griswold, Sergiu M. Gorun
  • Publication number: 20150071862
    Abstract: Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.
    Type: Application
    Filed: September 9, 2014
    Publication date: March 12, 2015
    Inventors: David Sabatino, Sergiu M. Gorun, Emily Borland, Hemantbhai Patel, Pradeepkumar Patel
  • Publication number: 20130064712
    Abstract: The present invention relates to a composite comprising at least one type of perfluoroalkyl-perfluoro-phthalocyanine, and to a method of producing such composite. The present invention also relates to a method of generating singlet oxygen, a method of killing eukaryotic or prokaryotic cells and a method of sterilization, cleaning and/or decontamination. Moreover, the present invention relates to a composite or a device for use in a method of sterilization, cleaning and/or decontamination.
    Type: Application
    Filed: October 12, 2010
    Publication date: March 14, 2013
    Inventors: Beate Roder, Sergiu M. Gorun, Robert Gerdes, Christian Litwinski
  • Patent number: 8349457
    Abstract: Perfluoroisopropyl-substituted perfluorophtalocyanines, including zinc (II), copper (II) and oxo-vanadium (IV) complexes of 29H,31H,1,4,8,11,15,18,22,25-octakis-fluoro-2,3,9,10,16,17,23,24-octakis-perfluoro(isopropyl)phthalocyanine (F64Pc), may be sublimed under high vacuum conditions. The compounds/molecules produce advantageous thin films (20-100 nm) on glass substrates by physical vapor deposition. Many potential applications of the disclosed compounds/molecules are disclosed, e.g., as semiconductor materials. In situ electrical conduction and optical transmission measurements during the deposition process reveal the formation of conducting pathways and potential microscopic intermolecular electronic couplings.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: January 8, 2013
    Assignee: New Jersey Institute of Technology
    Inventors: Sergiu M. Gorun, Olga Tsaryova, Lukasz Lapok
  • Publication number: 20120283430
    Abstract: Organo-metallic materials with reduced steric hindrance and the ability to aggregate ar disclosed. The metal remains capable of binding additional molecules. As an example, Zn complexes that prove aggregation are provided. Such aggregation may help improve or trigger new surface properties of the materials, alone or in combination with others. In a further implementation of the present disclosure, a robust molecule that resists degradation via nucleophilic, electrophilic and radical attacks is provided. Coordinated O2 is reduced catalytically, producing efficiently thyil radicals in spite of the extreme electronic deficiency of the catalyst.
    Type: Application
    Filed: November 1, 2011
    Publication date: November 8, 2012
    Applicant: NEW JERSEY INSTITUTE OF TECHNOLOGY
    Inventors: Sergiu M. Gorun, Andrei Ioan Loas, Kimberly Griswold, Lukasz Lapok, Hemantbhai Hasmukhbhai Patel, Robert Gerdes
  • Publication number: 20110172437
    Abstract: Advantageous methods for synthesis of fluorinated phthalocyanines are provided. Typical implementation involves a reaction mixture that includes perfluoro compound that is reacted for a reaction period sufficient to yield a fluorinated phthalocyanine of formula F64PcM, wherein “Pc” is any phthalocyanine macrocycle and “M” is hydrogen. Novel fluorinated phthalocyanine molecules/compounds are also provided herein, including specifically compounds that include fluorinated phthalocyanines wherein “M” is Cu or V?O. The fluorinated phthalocyanines have wide ranging applications, e.g., corrosion-related applications, coating-related applications, catalysis, and the production of optical and electronic materials.
    Type: Application
    Filed: April 1, 2009
    Publication date: July 14, 2011
    Applicant: NEW JERSEY INSTITUTE OF TECHNOLOGY
    Inventors: Sergiu M. Gorun, Robert Gerdes, Olga Gerdes, Lukasz Lapok
  • Publication number: 20110168543
    Abstract: Advantageous microwave-assisted methods for synthesis of fluorinated phthalocyanines are provided. The microwave-assisted methods offer enhanced yields, substantially eliminate reaction solvents, and facilitate purification relative to conventional synthesis techniques. Typical implementation involve a reaction mixture that includes perfluoro-phthalonitrile that is reacted in a vessel with application of microwave energy for a reaction period sufficient to yield a fluorinated phthalocyanine. The fluorinated phthalocyanines synthesized according to the disclosed microwave-assisted methods have wide ranging applications, e.g., corrosion-related applications, coating-related applications, catalysis, and the production of optical and electronic materials.
    Type: Application
    Filed: April 1, 2009
    Publication date: July 14, 2011
    Applicants: NEW JERSEY INSTITUTE OF TECHNOLOGY, FRAUNHOFER-GESELLSCHAFT
    Inventors: Sergiu M. Gorun, Guenter Schnurpfeil, Olaf Hild, Dieter Woehrle, Olga Gerdes, Robert Gerdes