Patents by Inventor Shai Lawit

Shai Lawit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210292754
    Abstract: Described herein are nonnaturally occurring nucleic acids that are and/or that provide a guide nucleic acid (e.g., a guide RNA). Further described herein are methods, compositions, systems (e.g., expression systems), and RNA structures (e.g., architectures), which may increase natural guide architecture (NGA) availability for Cas9 interactions.
    Type: Application
    Filed: March 16, 2021
    Publication date: September 23, 2021
    Inventors: Hae Jin Kim, Aaron Hummel, Shai Lawit, Aabid Shariff, Thomas Poorten, Nathaniel Graham
  • Publication number: 20210180079
    Abstract: Provided are compositions comprising polynucleotides encoding glutamine synthetase (GS) polypeptides having improved properties, such as increased enzymatic activity and/or increased thermostability. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides. Additionally, various methods of employing the polynucleotides in plants, such as methods for increasing GS activity in a plant, methods for increase seed protein content in a seed of a plant, and methods for increasing yield of a plant, are also provided herein.
    Type: Application
    Filed: May 20, 2019
    Publication date: June 17, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: STEVEN HENRY BASS, ERICKA BERMUDEZ, ZHENGLIN HOU, SHAI LAWIT, MARIAN BEECHER SANDOVAL, BO SHEN, PETER THELEN, YANG WANG, ROBERT W WILLIAMS, JINGRUI WU, JUN ZHANG
  • Publication number: 20210171971
    Abstract: Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
    Type: Application
    Filed: April 16, 2019
    Publication date: June 10, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: KRISTIN HAUG COLLET, ZHENGLIN HOU, SHAI LAWIT, ROSANA MELO, NICHOLAS MONGAR, JOHN VAN HEMERT, JINGRUI WU, WENGANG ZHOU
  • Publication number: 20210155949
    Abstract: Genome edited plants, plant cells, seeds and plant parts of maize are provided where expression levels and/or activities of MADS-box transcription factors are modulated to improve one or more agronomic characteristics such as grain yield. Also provided are compositions comprising polynucleotides encoding polypeptides and guide RNAs targeted to endogenous maize MADS-box proteins including for example, targeted site-directed mutagenesis using CRISPR-associated nucleases. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a maize plant and methods for increasing yield of a maize plant are also provided herein.
    Type: Application
    Filed: April 16, 2019
    Publication date: May 27, 2021
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: SHANE E ABBITT, MARY J FRANK, SHAI LAWIT, ROSANA MELO, MARY A RUPE, BO SHEN, JINGRUI WU
  • Publication number: 20150361442
    Abstract: This invention provides means for altering the harvest index of crop plants by modulating the expression of transgenic genes using dimerization domain and component stacks, thereby modulating plant architecture. The transgene/dimerization domain stacks are provided in a single transformation vector unit and are used to modulate plant growth, yield, and harvest index in plants.
    Type: Application
    Filed: September 2, 2015
    Publication date: December 17, 2015
    Inventors: Shai Lawit, Dwight Tomes
  • Patent number: 8778672
    Abstract: Compositions and methods for regulating expression of heterologous nucleotide sequences in a plant are provided. Compositions include nucleotide sequences for an Arabidopsis thaliana nucellar 1/inner integument (AT NUC1) promoter. Also provided is a method for expressing a heterologous nucleotide sequence in a plant using a promoter sequence disclosed herein.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: July 15, 2014
    Assignee: Pioneer Hi Bred International Inc
    Inventors: Shai Lawit, Mark Chamberlin
  • Publication number: 20110107458
    Abstract: Compositions and methods for regulating expression of heterologous nucleotide sequences in a plant are provided. Compositions include nucleotide sequences for an Arabidopsis thaliana nucellar 1/inner integument (AT NUC1) promoter. Also provided is a method for expressing a heterologous nucleotide sequence in a plant using a promoter sequence disclosed herein.
    Type: Application
    Filed: October 26, 2010
    Publication date: May 5, 2011
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: SHAI LAWIT, MARK CHAMBERLIN
  • Publication number: 20070266458
    Abstract: The invention provides isolated polynucleotide molecules encoding mutant and wild-type alleles of the maize D9 gene. The invention further provides methods for modifying the growth of plants involving the use of these isolated polynucleotide molecules, isolated polypeptides, and transformed plants, seeds, and cells.
    Type: Application
    Filed: April 18, 2007
    Publication date: November 15, 2007
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Shai Lawit, Suman Kundu, Aragula Rao, Dwight Tomes