Patents by Inventor Shalom Avraham

Shalom Avraham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neural cell protein marker RR/B and DNA encoding the same
    Patent number: 6066451
    Abstract: The invention contemplates the novel neural cell protein marker RR/B, cDNA encoding RR/B, nucleic acid probes for detection of mRNA encoding RR/B, synthetic polypeptides whose sequences correspond to a portion of RR/B and have a molecular weight equal to less than that of RR/B antibodies specific for RR/B, and methods for detection of RR/B.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: May 23, 2000
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Shalom Avraham, Hava Avraham, Jerome E. Groopman
  • Neural cell protein marker RR/B and DNA encoding same
    Patent number: 5863744
    Abstract: The invention contemplates the novel neural cell protein marker RR/B, cDNA encoding RR/B, nucleic acid probes for detection of mRNA encoding RR/B, synthetic polypeptides whose sequences correspond to a portion of RR/B and have a molecular weight equal to less than that of RR/B, and methods for detection of RR/B.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: January 26, 1999
    Assignee: New England Deaconess Hospital Corporation
    Inventors: Shalom Avraham, Hava Avraham, Jerome E. Groopman
  • Hematopoietic cell specific transcriptional regulatory elements of serglycin and uses thereof
    Patent number: 5340739
    Abstract: A negative transcription regulatory element (a constitutive suppressor) between residues -250 and -190 of the 5' flanking region of the mouse serglycin gene, a positive (hematopoietic cell enhancer) regulatory element located between residues -118 and -81, an equivalent of the TATA- box and a novel eukaryotic promoter that utilizes such equivalent, vectors containing such elements and hosts transformed therewith, are described. These regulatory elements, vectors and hosts are useful in gene transcription of heterologous genes in eukaryotic cells, and especially in hematopoietic cells. In addition, transcriptional factors that bind to these elements are described.
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: August 23, 1994
    Assignee: Brigham & Women's Hospital
    Inventors: Richard L. Stevens, Shalom Avraham