Patents by Inventor Shanger Wang

Shanger Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160338733
    Abstract: The present disclosure relates to a needle including a wall structure, a cutting edge and a blunt contour. The needle advantageously can be used to deliver a sensor (such as a glucose or other analyte sensor) through an outer skin layer and into a sensor depth in a less invasive way than prior art needles. The size of the cutting edge is balanced against a portion of the distal wall structure that has blunt contours. Thus, the needle is capable of cutting the more durable outer skin layer (first phase) and then progressively stretching open the cut for further advancement into the subcutaneous layer (second phase). When the needle is sufficiently advanced, it is retracted leaving the sensor in a desired position. Early testing has shown a reduction of “dip and recover” from glucose sensors delivered using the needle.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Inventors: Neel Shah, Jennifer Blackwell, Jonathan Hughes, Ted Tang Lee, Peter C. Simpson, Shanger Wang
  • Patent number: 9393311
    Abstract: The invention is directed to an intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): The invention is further directed to administering one or more pharmaceutically active substances to a patient in need thereof.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: July 19, 2016
    Assignees: DSM IP ASSETS B.V., DSM BIOMEDICAL INC.
    Inventors: Robert S. Ward, Shanger Wang, Li Li, Durgaprasad Chalasani, Patrick Kiser, Meredith Roberts Clark
  • Publication number: 20160120800
    Abstract: Intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): Also, method comprising administering one or more pharmaceutically active substances to a patient in need thereof.
    Type: Application
    Filed: January 12, 2016
    Publication date: May 5, 2016
    Applicant: DSM IP ASSETS B.V.
    Inventors: Robert S. WARD, Shanger WANG, Li Li, Durgaprasad CHALASANI, Patrick KISER, Meredith Roberts CLARK
  • Publication number: 20160113556
    Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.
    Type: Application
    Filed: December 9, 2015
    Publication date: April 28, 2016
    Inventors: Peter C. Simpson, Jennifer Blackwell, Sebastian Bohm, Michael J. Estes, Jeff Jackson, Jason Mitchell, Jack Pryor, Daiting Rong, Sean T. Saint, Disha B. Sheth, Shanger Wang
  • Patent number: 9255176
    Abstract: Polymer surface modification method comprising the steps of first forming a surface of primary reactive end groups tethered to the polymer chain ends during fabrication of an article, and then modifying the reactive surface with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, or polymers to attain specific surface properties. Alternatively, a multifunctional coupling agent can be used to couple the primary reactive group to a second reactive group capable of reacting with a functional group associated with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, and polymers to attain specific surface properties. The invention involves bringing reactive endgroups to the surface with surface active spacer attached to the polymer chain end. The surface active spacer allows the migration and enrichment of reactive end groups to the surface during fabrication.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: February 9, 2016
    Assignee: DSM IP ASSETS B.V.
    Inventors: Shanger Wang, Robert S. Ward, Yuan Tian, Xuwei Jiang, Keith McCrea, Scott Curtin
  • Publication number: 20150289788
    Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.
    Type: Application
    Filed: April 10, 2014
    Publication date: October 15, 2015
    Inventors: Peter C. Simpson, Jennifer Blackwell, Sebastian Bohm, Michael J. Estes, Jeff Jackson, Jason Mitchell, Jack Pryor, Daiting Rong, Sean T. Saint, Disha B. Sheth, Shanger Wang
  • Publication number: 20140350184
    Abstract: Polymer surface modification method comprising the steps of first forming a surface of primary reactive end groups tethered to the polymer chain ends during fabrication of an article, and then modifying the reactive surface with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, or polymers to attain specific surface properties. Alternatively, a multifunctional coupling agent can be used to couple the primary reactive group to a second reactive group capable of reacting with a functional group associated with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, and polymers to attain specific surface properties. The invention involves bringing reactive endgroups to the surface with surface active spacer attached to the polymer chain end. The surface active spacer allows the migration and enrichment of reactive end groups to the surface during fabrication.
    Type: Application
    Filed: August 8, 2014
    Publication date: November 27, 2014
    Inventors: Shanger WANG, Robert S. WARD, Yuan TIAN, Xuwei JIANG, Keith MCCREA, Scott CURTIN
  • Publication number: 20140213866
    Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.
    Type: Application
    Filed: April 10, 2014
    Publication date: July 31, 2014
    Inventors: Peter C. Simpson, Jennifer Blackwell, Sebastian Bohm, Michael J. Estes, Jeff Jackson, Jason Mitchell, Jack Pryor, Daiting Rong, Sean T. Saint, Disha B. Sheth, Shanger Wang
  • Publication number: 20140135408
    Abstract: Silicone containing reactive monomers with hydrophilic end-groups of formula I useful in the manufacture of biocompatible medical devices are disclosed, wherein R1 is H or CH3, a is 0 or 1, p is an integer from 1 to 6, q is an integer from 1 to 3 and for each q, the end groups R51, R52, R53 are independently an alkyl, alkyl ether, trimethylsiloxy group, or a substituted or non-substituted aromatic group and at least one of them has a hydrophilic group attached, preferably to the terminal end of R51, R52, R53, X is O or NR54, where R54 is H or a monovalent alkyl group with 1 to 4 carbons, n is an integer from 1 to 100, R2 and R3 are independently an alkyl, alkyl ether, or a substituted or non-substituted aromatic group, preferred R2 and R3 include methyl, ethyl, and phenyl, L is a divalent linker comprising substituted and unsubstituted alkylene groups having 1-14 carbon atoms, which may be straight or branched, substituted and unsubstituted alkoxy groups having 2-12 carbons, polyethers, oxazolines, and substi
    Type: Application
    Filed: February 1, 2012
    Publication date: May 15, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Shanger Wang, Xuwei Jiang, Yuan Tian
  • Publication number: 20140045792
    Abstract: The invention is directed to an intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): The invention is further directed to administering one or more pharmaceutically active substances to a patient in need thereof.
    Type: Application
    Filed: November 15, 2011
    Publication date: February 13, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Robert S. Ward, Shanger Wang, Li Li, Durgaprasad Chalasani, Patrick Kiser, Meredith Roberts Clark
  • Publication number: 20120095166
    Abstract: Polymers having the formula R(LE)X wherein R is a polymeric core having a number average molecular weight of from 5000 to 7,000,000 daltons and x endgroups, E is an endgroup that is covalently linked to polymeric core R by linkage L, L is a divalent oligomeric chain having at least 5 identical repeat units that is capable of self-assembly with L chains on adjacent molecules of the polymer, and the moieties (LE)X in the polymer may be the same as or different from one another. Monomers, oligomers, or other reactive structures otherwise analogous to known Self Assembled Monolayers but with at least one reactive chemical group capable of binding them to the terminus of a polymer, so that the thiol-free SAM analogue becomes the self-assembling surface modifying endgroup of that polymer, may be designed. Use of the polymer to fabricate a configured article from the surface-modified polymer or to fabricate a coating or topical treatment on an article made from another material.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 19, 2012
    Inventors: Robert S. WARD, Keith R. McCREA, Yuan TIAN, James P. PARAKKA, Shanger WANG
  • Publication number: 20110293522
    Abstract: Polymer surface modification method comprising the steps of first forming a surface of primary reactive end groups tethered to the polymer chain ends during fabrication of an article, and then modifying the reactive surface with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, or polymers to attain specific surface properties. Alternatively, a multifunctional coupling agent can be used to couple the primary reactive group to a second reactive group capable of reacting with a functional group associated with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, and polymers to attain specific surface properties. The invention involves bringing reactive endgroups to the surface with surface active spacer attached to the polymer chain end. The surface active spacer allows the migration and enrichment of reactive end groups to the surface during fabrication.
    Type: Application
    Filed: November 16, 2009
    Publication date: December 1, 2011
    Applicant: DSM IP ASSETS B.V.
    Inventors: Shanger Wang, Robert S. Ward, Yuan Tian, Xuwei Jiang, Keith Mccrea, Scott Curtin
  • Publication number: 20110124772
    Abstract: Polymers with non-leaching antimicrobial activity and their use as surface coatings or bulk resins for medical devices. The antimicrobial polymers are prepared with antimicrobial moieties covalently bonded to a polymer chain end or to a polymer backbone at a side chain end. The antimicrobial moiety-containing endgroups include surface active (or surface assembling) moieties which promote enrichment of antimicrobial endgroups at the polymer surface and thus formation of an antimicrobially active surface. Polymers with built-in antimicrobial endgroups can be used as bulk resins, as antimicrobial additives, or as infection preventative coatings in the manufacture of medical devices (e.g., catheters, vascular access devices, peripheral lines, IV sites, drains, gastric feeding and tubes, and other implantable devices).
    Type: Application
    Filed: May 26, 2009
    Publication date: May 26, 2011
    Applicant: DSM IP Assets B.V.
    Inventors: Shanger Wang, Robert S. Ward, Yuan Tian, Li Li, Keith Mccrea, James Parakka, Robert L. Jones, JR.
  • Patent number: 7902299
    Abstract: Single ion conductors comprising polymer electrolytes prepared by grafting a salt compound onto a comb-branch polymer or dendrimer are disclosed having superior properties.
    Type: Grant
    Filed: September 19, 2005
    Date of Patent: March 8, 2011
    Assignee: The Regents of the University of California
    Inventors: John Borland Kerr, Shanger Wang, Jun Hou, Steven Edward Sloop, Yong Bong Han, Gao Liu
  • Publication number: 20100179284
    Abstract: Medical device, prosthesis, or packaging assembly made up of polymer body comprising at least one polymer having the formula R(LE)x wherein R is a polymeric core having a number average molecular weight of from 5000 to 7,000,000 daltons, and having x endgroups, x is an integer?1, E is an endgroup which is covalently linked to polymeric core R by linkage L, L is a divalent oligomeric chain which has at least 5 repeat units and which can self-assembly with L chains on adjacent molecules of the polymer, and moieties L and/or E in the polymer(s) may be the same as or different from one another in composition and/or molecular weight. The polymer body includes plural polymer molecules located internally within the body, at least some of which internal polymer molecules have endgroups that form a surface of the body. The surface endgroups include at least one self-assembling moiety.
    Type: Application
    Filed: May 28, 2008
    Publication date: July 15, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Robert S. Ward, Keith McCrea, Yuan Tian, Shanger Wang, Larry Jones, Anfeng Wang, James P. Parakka
  • Publication number: 20090258048
    Abstract: Polymers having the formula R(LE)x wherein R is a polymeric core having a number average molecular weight of from 5000 to 7,000,000 daltons and having x endgroups, E is an endgroup covalently linked to polymeric core R by linkage L, L is a divalent oligomeric chain, having at least 5 identical repeat units, capable of self-assembly with L chains on adjacent molecules of the polymer, and the moieties (LE)x in the polymer may be the same as or different from one another. Design of monomers, oligomers, or other reactive structures otherwise analogous to known Self Assembled Monolayers but with at least one reactive chemical group capable of binding them to the terminus of a polymer, so that the thiol-free SAM analogue becomes the self-assembling surface modifying endgroup of that polymer. Use of the polymer to fabricate a configured article from the surface-modified polymer or a coating or topical treatment on an article made from another material.
    Type: Application
    Filed: December 7, 2006
    Publication date: October 15, 2009
    Applicant: The Polymer Technology Group, Inc.
    Inventors: Robert S. Ward, Keith R. McCrea, Yuan Tian, James P. Parakka, Shanger Wang
  • Patent number: 7368589
    Abstract: The present invention relates to a process for the purification of silicone containing compounds via supercritical fluid extraction. Specifically, the present invention relates to a process comprising the steps of contacting at least one silicone containing compound with a supercritical fluid having a density of between about 0.2 and about 0.8 g/ml, decreasing said density so that two phases are formed a first phase comprising said at least one silicone containing compound and a second phase comprising at least one impurity and separating said second phase from said first phase.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: May 6, 2008
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Shivkumar Mahadevan, Frank Molock, Robert S. Ward, Yuan Tian, Shanger Wang, James M. Serpilio, Jr.
  • Publication number: 20070265460
    Abstract: The present invention relates to a process comprising the steps of reacting in the presence of a hydrosilylation catalyst, a first reaction mixture comprising a free radical reactive compound and a silicon containing compound to form a silicon substituted glyceryl (meth)acrylate.
    Type: Application
    Filed: July 25, 2007
    Publication date: November 15, 2007
    Inventors: Shivkumar Mahadevan, Robert Ward, Shanger Wang, James Parakka, Yuan Tian, Frank Molock
  • Patent number: 7101643
    Abstract: New polymer electrolytes were prepared by in situ cross-linking of allyl functional polymers based on hydrosilation reaction using a multifunctional silane cross-linker and an organoplatinum catalyst. The new cross-linked electrolytes are insoluble in organic solvent and show much better mechanical strength. In addition, the processability of the polymer electrolyte is maintained since the casting is finished well before the gel formation.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: September 5, 2006
    Assignee: The Regents of the University of California
    Inventors: John Borland Kerr, Shanger Wang, Jun Hou, Steven Edward Sloop, Yong Bong Han, Gao Liu
  • Publication number: 20060047134
    Abstract: The present invention relates to a process comprising the steps of reacting in the presence of a hydrosilylation catalyst, a first reaction mixture comprising a free radical reactive compound and a silicon containing compound to form a silicon substituted glyceryl (meth)acrylate.
    Type: Application
    Filed: August 25, 2004
    Publication date: March 2, 2006
    Inventors: Frank Molock, Shivkumar Mahadevan, Robert Ward, Shanger Wang, James Parakka, Yuan Tian