Patents by Inventor Shangqin Guo

Shangqin Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8828965
    Abstract: The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor cells respectively.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: September 9, 2014
    Assignees: The General Hospital Corporation, Dana-Farber Cancer Institute, Massachusetts Institute of Technology
    Inventors: Jun Lu, Shangqin Guo, Benjamin Ebert, David Scadden, Todd Golub
  • Publication number: 20140050707
    Abstract: The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor cells respectively.
    Type: Application
    Filed: August 21, 2013
    Publication date: February 20, 2014
    Applicants: THE GENERAL HOSPITAL CORPORATION, DANA-FARBER CANCER INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Jun Lu, Shangqin Guo, Benjamin Ebert, David Scadden, Todd Golub
  • Patent number: 8530443
    Abstract: The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor cells respectively.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: September 10, 2013
    Assignees: The General Hospital Corporation, Massachusetts Institute of Technology, Dana-Farber Cancer Institute, Inc.
    Inventors: Jun Lu, Shangqin Guo, Benjamin Ebert, David Scadden, Todd Golub
  • Publication number: 20130039895
    Abstract: The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor cells respectively.
    Type: Application
    Filed: October 16, 2012
    Publication date: February 14, 2013
    Applicants: THE GENERAL HOSPITAL CORPORATION, DANA-FARBER CANCER INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Jun Lu, Shangqin Guo, Benjamin Ebert, David Scadden, Todd Golub
  • Publication number: 20110280861
    Abstract: Embodiments of the invention relate to methods and compositions for the expansion of hematopoietic stem cell (HSC) self renewal. The microRNA-125a is a master control of HSC self-renewal. Increased expression of mir-125a increased HSC self-renewal by 6-30 folds. Increased expression of mir-125a can be used to expand HSC ex vivo and in vivo.
    Type: Application
    Filed: August 10, 2009
    Publication date: November 17, 2011
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE GENERAL HOSPITAL CORPORATION
    Inventors: David Scadden, Shangqin Guo, Jun Lu
  • Publication number: 20090202493
    Abstract: The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor cells respectively.
    Type: Application
    Filed: January 30, 2009
    Publication date: August 13, 2009
    Applicants: THE GENERAL HOSPITAL CORPORATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGY, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Jun Lu, Shangqin Guo, Benjamin Ebert, David Scadden, Todd Golub