Patents by Inventor Shanta Boddapati

Shanta Boddapati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONTROLLED FUCOSYLATION OF ANTIBODIES
    Publication number: 20220081477
    Abstract: The invention provides methods for preparing antibodies and antibody derivatives with controlled levels of core fucosylation. In one aspect, provided herein is a method of controlling the level of afucosylation of an antibody or antibody derivative. In some embodiments, the invention provides a composition of antibodies or antibody derivatives produced by the instant methods. The antibodies and derivatives can be formulated as pharmaceutical compositions comprising a therapeutically or prophylactically effective amount of the antibody or derivative and one or more pharmaceutically acceptable ingredients.
    Type: Application
    Filed: December 18, 2019
    Publication date: March 17, 2022
    Inventors: Shanta BODDAPATI, Aaron CHEN, Swapnil BHARGAVA
  • Bispecific nanobodies as a therapeutic for alzheimer's disease
    Patent number: 8617549
    Abstract: The present invention provides for the treatment of Alzheimer's disease. More specifically, a recombinant bispecific antibody fragment that simultaneously blocks beta-secretase activity while also promoting alpha-secretase activity, comprising a first portion and a second portion, wherein the first portion blocks beta secretase activity and the second portion promotes alpha-secretase activity.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: December 31, 2013
    Assignee: Arizona Board of Regents, A Body Corporate of the State of Arizona, Acting for and on behalf of Arizona State University
    Inventors: Michael Sierks, Shanta Boddapati, Srinath Kasturirangan
  • BISPECIFIC NANOBODIES AS A THERAPEUTIC FOR ALZHEIMER'S DISEASE
    Publication number: 20120230999
    Abstract: The present invention provides for the treatment of Alzheimer's disease. More specifically, a recombinant bispecific antibody fragment that simultaneously blocks beta-secretase activity while also promoting alpha-secretase activity, comprising a first portion and a second portion, wherein the first portion blocks beta secretase activity and the second portion promotes alpha-secretase activity.
    Type: Application
    Filed: September 8, 2010
    Publication date: September 13, 2012
    Applicant: Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Ariz
    Inventors: Michael Sierks, Shanta Boddapati, Srinath Kasturirangan