Patents by Inventor Sharad Magar

Sharad Magar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazine derivatives and methods of use
    Patent number: 8946227
    Abstract: The invention provides 2-carboxamide piperazine compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: February 3, 2015
    Assignee: Merck Serono SA
    Inventors: Sharad Magar, Andreas Goutopoulos, Yihua Liao, Matthias Schwarz, Russell J. Thomas
  • PIPERAZINE DERIVATIVES AND METHODS OF USE
    Publication number: 20130143893
    Abstract: The invention provides 2-carboxamide piperazine compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility.
    Type: Application
    Filed: January 30, 2013
    Publication date: June 6, 2013
    Applicant: MERCK SERONO SA
    Inventors: Sharad Magar, Andreas Goutopoulos, Yihua Liao, Matthias Schwarz, Russell J. Thomas
  • PIPERAZINE DERIVATIVES AND METHODS OF USE
    Publication number: 20100305137
    Abstract: The invention provides 2-carboxamide piperazine compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility.
    Type: Application
    Filed: June 2, 2010
    Publication date: December 2, 2010
    Applicant: MERCK SERONO SA
    Inventors: Sharad Magar, Andreas Goutopulos, Yihua Liao, Matthias Schwarz, Russel J. Thomas
  • Piperazine derivatives and methods of use
    Patent number: 7754722
    Abstract: The invention provides 2-carboxamide piperazine compounds of formula I, R3.IN\?N˜?R2I(0)z-oR4I wherein R?, R2, R3 and R4 are as defined in the claims and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: July 13, 2010
    Assignee: Merck Serono SA
    Inventors: Sharad Magar, Andreas Goutopoulos, Yihua Liao, Matthias Schwarz, Russell J. Thomas
  • Azole derivatives and pharmaceutical compositions containing them
    Patent number: 7541375
    Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
    Type: Grant
    Filed: July 24, 2007
    Date of Patent: June 2, 2009
    Assignee: Laboratoires Serono SA
    Inventors: Stephen J. Arkinstall, Antonio Arulanandam, Xuliang Jiang, Sharad Magar, Roustem Nabioullin, John Yingsheng Zhang, Peter Blume-Jensen
  • Therapeutic guanidines
    Patent number: 7351743
    Abstract: The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: April 1, 2008
    Assignee: Wyeth
    Inventors: Stanley M. Goldin, James B. Fischer, Andrew Gannett Knapp, N. Laxma Reddy, David Berlove, Graham J. Durant, Subbarao Katragadda, Lain-Yen Hu, Sharad Magar, Wenhong Fan, Elizabeth Yost, Juo Qing Guo
  • AZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20070293555
    Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
    Type: Application
    Filed: July 24, 2007
    Publication date: December 20, 2007
    Applicant: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
    Inventors: Stephen ARKINSTALL, Antonio Arulanandam, Xuliang Jiang, Sharad Magar, Roustem Nabioullin, John Zhang, Peter Blume-Jensen
  • Therapeutic guanidines
    Publication number: 20070265348
    Abstract: The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.
    Type: Application
    Filed: July 19, 2007
    Publication date: November 15, 2007
    Inventors: Stanley Goldin, James Fischer, Andrew Knapp, N. Laxma Reddy, David Berlove, Graham Durant, Subbarao Katragadda, Lain-Yen Hu, Sharad Magar, Wenhong Fan, Elizabeth Yost, Jun Qing Guo
  • Azole derivatives and pharmaceutical compositions containing them
    Patent number: 7253199
    Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: August 7, 2007
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Stephen J. Arkinstall, Antonio Arulanandam, Xuliang Jiang, Sharad Magar, Roustem Nabioullin, John Yingsheng Zhang, Peter Blume-Jensen
  • Piperazine Derivatives and Methods of Use
    Publication number: 20060223813
    Abstract: The invention provides 2-carboxamide piperazine compounds of formula I, R3. I N\? N˜? R2I(0)z- o R4 I wherein R?, R2, R3 and R4 are as defined in the claims and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility.
    Type: Application
    Filed: September 19, 2003
    Publication date: October 5, 2006
    Inventors: Sharad Magar, Andreas Goutopoulos, Matthias Schwarz, Russell Thomas
  • Pharmaceutically active compounds and methods of use
    Publication number: 20050054706
    Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
    Type: Application
    Filed: October 23, 2002
    Publication date: March 10, 2005
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Stephen Arkinstall, Antonio Arulanandam, Xuliang Jiang, Sharad Magar, Roustem Nabioullin, John Zhang, Peter Blume-Jensen
  • Therapeutic guanidines
    Patent number: 6787569
    Abstract: The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: September 7, 2004
    Assignee: Cambridge NeuroScience, Inc.
    Inventors: Stanley M. Goldin, James B. Fischer, Andrew Gannett Knapp, N. Laxma Reddy, David Berlove, Graham J. Durant, Subbarao Katragadda, Lain-Yen Hu, Sharad Magar, Wenhong Fan, Elizabeth Yost, Jun Qing Guo
  • Pharmaceutically active compounds and methods of use
    Patent number: 6770668
    Abstract: The present invention relates to pharmaceutically acceptable compounds, including certain substituted indolinyl and derivatives thereof, 1,2,3,4-tetrahydroquinolinyl and derivatives thereof, 1,2,3,4-tetrahydroisoquinolinyl, benz[cd]indolinyl and 5,6-dihydrophenanthridinyl compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: August 3, 2004
    Inventors: N. Laxma Reddy, Michael Maillard, David Berlove, Sharad Magar, Graham J. Durant
  • FSH mimetics for the treatment of infertility
    Patent number: 6653338
    Abstract: “The present invention provides non-peptidic amino derivatives, their therapeutic use as well as pharmaceutical compositions that possess activity as Follicle Stimulating Hormone (FSH) agonists and are useful in the treatment of infertility. In particular, the invention provides derivatives.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: November 25, 2003
    Assignee: Applied Research Systems ARS Holding N.A.
    Inventors: Nabil El Tayer, Adulla Reddy, David Buckler, Sharad Magar
  • Pharmaceutically active compounds and methods of use
    Publication number: 20030153763
    Abstract: The present invention relates to pharmaceutically acceptable compounds, including certain substituted indolinyl and derivatives thereof, 1,2,3,4-tetrahydroquinolinyl and derivatives thereof, 1,2,3,4-tetrahydroisoquinolinyl, benz[cd]indolinyl and 5,6-dihydrophenanthridinyl compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
    Type: Application
    Filed: December 17, 2002
    Publication date: August 14, 2003
    Inventors: N. Laxma Reddy, Michael Maillard, David Berlove, Sharad Magar, Graham J. Durant
  • Pharmaceutically active compounds and methods of use
    Patent number: 6514990
    Abstract: The present invention relates to pharmaceutically acceptable compounds, including certain substituted indolinyl and derivatives thereof, 1,2,3,4-tetrahydroquinolinyl and derivatives thereof, 1,2,3,4-tetrahydroisoquinolinyl, benz[cd]indolinyl and 5,6-dihydrophenanthridinyl compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: February 4, 2003
    Assignee: Scion Pharmaceuticals, Inc.
    Inventors: N. Laxma Reddy, Michael Maillard, David Berlove, Sharad Magar, Graham J. Durant
  • FSH mimetics for the treatment of infertility
    Publication number: 20020147345
    Abstract: The present invention provides non-peptidic amino derivatives, their therapeutic use as well as pharmaceutical compositions that possess activity as Follicle Stimulating Hormone (FSH) agonists and are useful in the for treatment of infertility. In particular, the invention provides cyclic and acyclic alpha- and beta-aminocarboxamides, more particularly tetrahydroisoquinolinecarboxamides, piperidinecarboxamides, pyrrolidinecarboxamides, and 2-amino-3-carboxamidopyridine derivatives.
    Type: Application
    Filed: May 28, 2002
    Publication date: October 10, 2002
    Inventors: Nabil El Tayer, Adulla Reddy, David Buckler, Sharad Magar
  • Pharmaceutically active compounds and methods of use
    Publication number: 20020099084
    Abstract: The present invention relates to pharmaceutically acceptable compounds, including certain substituted indolinyl and derivatives thereof, 1,2,3,4-tetrahydroquinolinyl and derivatives thereof, 1,2,3,4-tetrahydroisoquinolinyl, benz[cd]indolinyl and 5,6-dihydrophenanthridinyl compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
    Type: Application
    Filed: November 9, 2001
    Publication date: July 25, 2002
    Inventors: N. Laxma Reddy, Michael Maillard, David Berlove, Sharad Magar, Graham J. Durant
  • FSH mimetics for the treatment of infertility
    Patent number: 6423723
    Abstract: The present invention provides non-peptidic amino derivatives, their therapeutic use as well as pharmaceutical compositions that possess activity as Follicle Stimulating Hormone (FSH) agonists and are useful in the for treatment of infertility. In particular, the invention provides cyclic and acyclic alpha- and beta-aminocarboxamides, more particularly tetrahydroisoquinolinecarboxamides, piperidinecarboxamides, pyrrolidinecarboxamides, and 2-amino-3-carboxamidopyridine derivatives.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: July 23, 2002
    Assignee: Applied Research Systems ARS Holding N. A.
    Inventors: Nabil El Tayer, Adulla Reddy, David Buckler, Sharad Magar
  • Pharmaceutically active nitrogen ring compounds and methods of use thereof
    Patent number: 6358993
    Abstract: The present invention relates to pharmaceutically acceptable compounds, including certain substituted indolinyl and derivatives thereof, 1,2,3,4-tetrahydroquinolinyl and derivatives thereof, 1,2,3,4-tetrahydroisoquinolinyl, benz[cd]indolinyl and 5,6-dihydrophenanthridinyl compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: March 19, 2002
    Assignee: CeNes Pharmaceuticals, Inc.
    Inventors: N. Laxma Reddy, Michael Maillard, David Berlove, Sharad Magar, Graham J. Durant