Patents by Inventor Sheau-Farn Yeh

Sheau-Farn Yeh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-substituted 1,2,3,4-tetrahydro-&bgr;-carboline and 3,4-dihydro-&bgr;-carboline and analogs as antitumor agents
    Patent number: 6720331
    Abstract: A composition includes a substituted dihydro- or tetrahydro-&bgr;-carboline of formula (II) or (III), wherein the aromatic ring of the carboline may include one or more substituents selected from the group consisting of hydroxy, C1-6 alkoxy, benzyloxy, C1-6 acyloxy, amino, C1-6 alkyl, C1-6 dialkylamino, halogen, and carboxy, and the C-1 position of the carboline may include a substitutent selected from the group consisting of a carbocyclic group and a heterocyclic group. The composition may include a salt or a prodrug of the substituted dihydro- or tetrahydro-&bgr;-carboline. The composition may further includes a pharmaceutically acceptable carrier, diluent, or excipient.
    Type: Grant
    Filed: April 3, 2002
    Date of Patent: April 13, 2004
    Assignees: National Sun Yat-sen University, National Yang-Ming University
    Inventors: Sheau Farn Yeh, Ya-Ching Shen
  • 1-substituted 1,2,3,4-tetrahydro-beta-carboline and 3,4-dihydro-beta-carboline and analogs as antitumor agents
    Publication number: 20030040527
    Abstract: A composition includes a substituted dihydro- or tetrahydro-&bgr;-carboline of formula (II) or (III), wherein the aromatic ring of the carboline may include one or more substituents selected from the group consisting of hydroxy, C1-6 alkoxy, benzyloxy, C1-6 acyloxy, amino, C1-6 alkyl, C1-6 dialkylamino, halogen, and carboxy, and the C-1 position of the carboline may include a substitutent selected from the group consisting of a carbocyclic group and a heterocyclic group. The composition may include a salt or a prodrug of the substituted dihydro- or tetrahydro-&bgr;-carboline. The composition may further includes a pharmaceutically acceptable carrier, diluent, or excipient.
    Type: Application
    Filed: April 3, 2002
    Publication date: February 27, 2003
    Inventors: Sheau Farn Yeh, Ya-Ching Shen
  • Inhibition and treatment of Hepatitis B virus and Flavivirus by Helioxanthin and its analogs
    Patent number: 6306899
    Abstract: This invention relates to anti-viral drugs such as Helioxanthin and its analogs. The present compounds may be used alone or in combination with other drugs for the treatment of Hepatitis B virus (HBV), Hepatitis C virus (HCV), Yellow Fever, Dengue Virus, Japanese Encephalitis, West Nile virus and related flaviviruses. In addition, compounds according to the present invention can be used to prevent hepatoma secondary to virus infection as well as other infections or disease states which are secondary to the virus infection.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: October 23, 2001
    Assignees: Yale University, N. Y. Mu, N.T.U., V.G.H
    Inventors: Yung-Chi Cheng, Chen-Kung Chou, Lei Fu, Yueh-Hsiung Kuo, Sheau-Farn Yeh, Juliang Zhu, Yonglian Zhu
  • Method of protecting cells and tissues by a triacylglycerol preparation
    Patent number: 5585399
    Abstract: The present invention relates to a method of using a preparation of triacylglycerol which contains unsaturated fatty acids having no more than two double bonds to preserve normal erythrocyte deformability, to improve microcirculation, to protect myocardium against ischemic damage and to suppress arrhythmia in ischemic heart, i.e. to protect cells and tissues of a mammalian body against various forms of mechanical and chemical injuries.
    Type: Grant
    Filed: January 18, 1994
    Date of Patent: December 17, 1996
    Inventors: Chuang-Ye Hong, Li-Ju Lai, Sheau-Farn Yeh