Patents by Inventor Sheng Zhou

Sheng Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240121870
    Abstract: A self-adaptive constant-current driving circuit for a three-channel multi-color LED, including a decoder, a two-phase non-overlapping circuit, and a LED constant-current driving circuit, where the decoder determines the number of lighted channels according to a first input signal, and generates a first switch control signal and a second switch control signal; the two-phase non-overlapping circuit modulates the first switch control signal into a first two-phase non-overlapping signal and a second two-phase non-overlapping signal, and modulates the second switch control signal into a third two-phase non-overlapping signal and a fourth two-phase non-overlapping signal; the LED constant-current driving circuit controls an on/off state of the respective channel of LED according to a second input signal, and outputs a current for controlling a brightness of the respective channel of LED according to the first two-phase non-overlapping signal, the second two-phase non-overlapping signal, the third two-phase non-ove
    Type: Application
    Filed: December 15, 2021
    Publication date: April 11, 2024
    Applicant: CRM ICBG(WUXI)CO., LTD.
    Inventors: ZHENLI LIU, SHENG ZHOU, DONGMIN DING, PENGFEI CAI
  • Publication number: 20240117043
    Abstract: The present disclosure provides a bispecific antibody including a binding domain that binds to CD112R and a binding domain that binds to TIGIT, and the binding domain that binds to CD112R includes: HCDR1, HCDR2 and HCDR3 of the amino acid sequence set forth in SEQ ID NO: 1, and/or LCDR1, LCDR2 and LCDR3 of the amino acid sequence set forth in SEQ ID NO: 2; and the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are defined according to the Kabat, IMGT, Chothia, AbM or Contact numbering system. The present disclosure further provides a polynucleotide encoding the antibody, an expression vector, a host cell and a method for expressing and purifying the antibody, a pharmaceutical composition including the antibody of the present disclosure, and use of the bispecific antibody for treating cancer.
    Type: Application
    Filed: August 4, 2023
    Publication date: April 11, 2024
    Applicants: SHANGHAI JUNSHI BIOSCIENCES CO., LTD., SUZHOU JUNMENG BIOSCIENCES CO., LTD.
    Inventors: Dandan LIU, Jinwei ZHOU, Yuehua ZHOU, Jing ZHANG, Sheng YAO, Hui FENG, Hui LIU, Hongchuan LIU, Li LI, Qiang ZHAO
  • Publication number: 20240118498
    Abstract: The present disclosure relates to a distribution cable assembly that has various features to enable flexible configurations to accommodate various data center configurations.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 11, 2024
    Inventors: Lan Bo, Songhua Cao, Ke Jiang, Xu Li, Wei Liu, Peiyou Xiong, Wei Zhang, Shun Sheng Zhou
  • Patent number: 11954530
    Abstract: The present disclosure provides a method of processing data based on QUIC protocol stack, the method including: obtaining a connection identifier of a data packet; determining a server program used for processing the data packet, wherein the server program comprises a plurality of worker threads, wherein QUIC protocol stacks run in the plurality of worker threads; determining a corresponding worker thread from the multiple worker threads based on the connection identifier; and distributing the data packet to the corresponding worker thread to make the QUIC protocol stack on the corresponding worker thread process the data packet. The disclosure further provides a system, a computing device and a computer-readable storage medium of processing data based on QUIC protocol stack.
    Type: Grant
    Filed: December 25, 2019
    Date of Patent: April 9, 2024
    Assignee: SHANGHAI BILIBILI TECHNOLOGY CO., LTD.
    Inventors: Sheng Wang, Quan Zhou, Shangzhi Cai
  • Publication number: 20240091569
    Abstract: Methods, apparatuses, systems, and/or the like are provided. An example method may include installing one or more filter cartridges in a blower device. An example blower device may include a housing defining at least one air inlet. An example filter cartridge may include a first filter cartridge defining a first outlet opening. The first filter cartridge may be configured to slidably engage the blower device to align the first outlet opening with at least a first portion of the at least one air inlet of the blower device in a first installed position. The one or more filter cartridges my include a second filter cartridge. The second filter cartridge may include a second outlet opening. The example method may include aligning the first outlet opening of the first filter cartridge with at least the first portion of the at least one air inlet of the blower device.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 21, 2024
    Inventors: Siwei WANG, Xiaojin HAN, Hongbing XIANG, Sheng ZHOU, Anker CHEN
  • Publication number: 20240079091
    Abstract: Various examples are provided related to phosphosite prediction. In one example, a system includes a computing device and an application for phosphosite prediction stored in memory. When executed, the application can cause the computing device to transform a protein sequence to a context-aware protein sequence by a Phosformer based transformer. The transformation can include predicting phosphorylation associations from the protein sequence based upon a trained Phosformer model and generating the context-aware protein sequence based upon the predicted phosphorylation associations, the context-aware protein sequence including a predicted phosphosite. The predicted phosphosite can be rendered for presentation to a user.
    Type: Application
    Filed: September 6, 2023
    Publication date: March 7, 2024
    Inventors: Natarajan Kannan, Zhongliang Zhou, Sheng Li, Wayland Yeung
  • Patent number: 11880082
    Abstract: The present disclosure relates to a distribution cable assembly that has various features to enable flexible configurations to accommodate various data center configurations.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: January 23, 2024
    Assignee: Corning Research & Development Corporation
    Inventors: Songhua Cao, Xu Li, Wei Liu, Peiyou Xiong, Shun Sheng Zhou
  • Publication number: 20230398382
    Abstract: Various embodiments described herein are directed to a face mask assembly configured with a drop-down feature and methods of using the same. In various embodiments, a face mask assembly comprises a face mask configured for dynamic engagement with a first strap of a strap assembly such that the face mask is configured for selective movement along a strap length of the first strap between a donned position and a drop-down position, the face mask comprising: a first strap pathway configured to receive at least a portion of the first strap and a strap engagement tongue positioned along the first strap pathway and comprising a plurality of strap engagement teeth protruding from of the interior tongue surface; wherein the face mask is configured to be selectively adjustable between a dynamic configuration and a locked configuration based on the arrangement of the first strap relative to the strap engagement tongue.
    Type: Application
    Filed: June 5, 2023
    Publication date: December 14, 2023
    Inventors: Chuang MA, Sheng ZHOU, Hongbing XIANG, Xiaojin HAN, Siwei WANG
  • Publication number: 20230181762
    Abstract: A construct including a genomic insulator element that exhibits strong enhancer blocking activities in T lymphocytes is provided as are host cells, pharmaceutical compositions and methods of using the construct in the treatment of disease, in particular a disease to be treated with a retroviral vector-modified T lymphocyte.
    Type: Application
    Filed: May 7, 2021
    Publication date: June 15, 2023
    Inventors: Sheng ZHOU, Brian SORRENTINO, Yong CHENG
  • Publication number: 20230159875
    Abstract: A conjugation device includes at least one flow reactor having an inlet and an outlet, the flow reactor(s) being completely filled with a support such as a matrix including 1) chromatography beads, fibers or membranes, and 2) a biologic catalyzer, namely the enzyme ligase, which is immobilized onto this support; a fluid delivery unit in fluid communication with the inlet of the flow reactor(s) and configured to continuously provide the flow reactor(s) with at least one kind of reaction fluid such as antibody and linker-payload according to stages of the conjugation process, the at least one kind of process fluid including a first moiety and a second moiety of a conjugate to be produced; and a fluid collection unit in fluid communication with the outlet of the flow reactor(s) and configured to control collection of fluid flowing out of the outlet of the flow reactor(s) according to the stages of the conjugation process.
    Type: Application
    Filed: January 5, 2023
    Publication date: May 25, 2023
    Inventors: Gang QIN, Sheng ZHOU, Cao LV, Joachim WALTER
  • Patent number: 11578297
    Abstract: A conjugation device includes at least one flow reactor having an inlet and an outlet, the flow reactor(s) being completely filled with a support such as a matrix including 1) chromatography beads, fibers or membranes, and 2) a biologic catalyzer, namely the enzyme ligase, which is immobilized onto this support; a fluid delivery unit in fluid communication with the inlet of the flow reactor(s) and configured to continuously provide the flow reactor(s) with at least one kind of reaction fluid such as antibody and linker-payload according to stages of the conjugation process, the at least one kind of process fluid including a first moiety and a second moiety of a conjugate to be produced; and a fluid collection unit in fluid communication with the outlet of the flow reactor(s) and configured to control collection of fluid flowing out of the outlet of the flow reactor(s) according to the stages of the conjugation process.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: February 14, 2023
    Assignees: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD., LISURE SCIENCE (SUZHOU) CO., LTD
    Inventors: Gang Qin, Sheng Zhou, Cao Lv, Joachim Walter
  • Patent number: 11537622
    Abstract: K-NN spatial queries may be performed, and the results of one K-NN query are re-used to perform a plurality of K-NN queries on a set of query points. More specifically, a K-NN query is performed on a pre-defined location, for example, an object point, to find the nearest K data objects for this pre-defined location, the results of this K-NN query being used to perform further K-NN queries on the query points near the pre-defined location. In doing so, the efficiency of large scale K-NN spatial queries is improved by limiting the spatial search range of the K-NN queries to be performed and re-using pre-computed K-NN data.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: December 27, 2022
    Assignee: Ordnance Survey Limited
    Inventor: Sheng Zhou
  • Patent number: 11449566
    Abstract: A computer-implemented method and system for generating partition polygons across a geographic area, wherein a concave hull of the reference network, usually a network of linear features such as roads, and the spatial data objects to be processed is first generated, the resulting concave hull thereby providing the boundary geometry for the final partition scheme. By generating a concave hull from the reference network and the spatial data objects, it is possible to derive a boundary that is based on the spatial position of the reference network and the spatial data objects at the periphery of the geographic area that they cover, that is, the boundary itself connects at least a portion of the end points of the reference network and the spatial data objects.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: September 20, 2022
    Assignee: Ordnance Survey Limited
    Inventor: Sheng Zhou
  • Publication number: 20220257052
    Abstract: A method for controlling a cooking apparatus includes counting a number of times that an operation temperature of the cooking apparatus exceeds a set temperature within a previous set duration, updating a control parameter corresponding to a current set duration based on the number of times, and controlling a heating device of the cooking apparatus to heat within the current set duration based on the updated control parameter.
    Type: Application
    Filed: November 8, 2019
    Publication date: August 18, 2022
    Inventors: Maoqiao TIAN, Yongdong AI, Xiang WU, Longjian XUAN, Jie LI, Wei CHEN, Xiaohui LI, Biao WANG, Sheng ZHOU, Xianxin MENG, Yanxia ZENG, Fuxing YANG, Wenqi TIAN, Weijie LU
  • Patent number: 11418023
    Abstract: A current protection circuit for a high voltage system includes: a power supply module to supply power to a load through a high voltage bus and a low voltage bus; a detection module connected to the high voltage bus and used to detect a value of current flowing through the high voltage bus; a signal processing module electrically connected to the detection module and used to amplify the current flowing through the high voltage bus; and a control module electrically connected to the signal processing module, the power supply module, and the load, and used to disconnect the load from the power supply module or perform current limiting for the load when the value of the amplified current exceeds a preset threshold.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: August 16, 2022
    Assignee: UBTECH ROBOTICS CORP LTD
    Inventors: Youjun Xiong, Sheng Zhou, Malin Wang, Wenhua Fan, Jianxin Pang
  • Publication number: 20220251494
    Abstract: A conjugation device includes at least one flow reactor having an inlet and an outlet, the flow reactor(s) being completely filled with a support such as a matrix including 1) chromatography beads, fibers or membranes, and 2) a biologic catalyzer, namely the enzyme ligase, which is immobilized onto this support; a fluid delivery unit in fluid communication with the inlet of the flow reactor(s) and configured to continuously provide the flow reactor(s) with at least one kind of reaction fluid such as antibody and linker-payload according to stages of the conjugation process, the at least one kind of process fluid including a first moiety and a second moiety of a conjugate to be produced; and a fluid collection unit in fluid communication with the outlet of the flow reactor(s) and configured to control collection of fluid flowing out of the outlet of the flow reactor(s) according to the stages of the conjugation process.
    Type: Application
    Filed: February 9, 2022
    Publication date: August 11, 2022
    Inventors: Gang QIN, Sheng ZHOU, Cao LV, Joachim WALTER
  • Patent number: 11293623
    Abstract: The present invention provides a light projection structure, in which an auxiliary lamp device is disposed on one side of a main lamp device. The main lamp device projects a first light pattern and the auxiliary lamp device projects a second light pattern. The second light pattern includes a gap. The first light pattern projected by the main lamp device is projected onto the gap, so that the main lamp device and the auxiliary lamp device combined can broaden the light projection range, and hence producing more uniform light patterns as well as increasing the light illumination area.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: April 5, 2022
    Assignee: T.Q. Optoelectronics Co., Ltd.
    Inventors: Hung-Chieh Chen, Zhan-Sheng Zhou, Ji-Pin Wang, Huan-Ping Chiu
  • Patent number: 11268158
    Abstract: The invention is directed to methods of assessing the safety of therapeutic compounds and therapeutic genetic manipulations, including integrating gene therapy vectors and genome editing. In particular, the invention provides a method, wherein the oncogenic potential of therapeutic compounds and therapeutic genetic manipulations, including integrating gene therapy vectors and genome editing, is determined by determining the percentage of differentiation blocked hematopoietic progenitor cells.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: March 8, 2022
    Assignee: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
    Inventors: Brian P. Sorrentino, Sheng Zhou
  • Patent number: D963242
    Type: Grant
    Filed: February 2, 2021
    Date of Patent: September 6, 2022
    Inventors: Wen-Sheng Zhou, Bin Chen, Liang Peng
  • Patent number: D971618
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: December 6, 2022
    Inventor: Sheng Zhou