Patents by Inventor Shibao Yang

Shibao Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10206905
    Abstract: The present invention relates to the use of a composition for preparing a medicament for the treatment of amyotrophic lateral sclerosis and associated disorders. The composition comprises 3-methyl-1-phenyl-2-pyrazoline-5-one or pharmaceutically acceptable salts thereof and borneol. The medicament is a drug used for delaying the occurrence time of amyotrophic lateral sclerosis and extending the survival time, and for improving memory function defect of amyotrophic lateral sclerosis.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: February 19, 2019
    Assignee: JIANGSU SIMCERE PHARMACEUTICAL CO., LTD
    Inventors: Shibao Yang, Yao Hua, Zhengping Zhang, Rong Chen, Zhaolong Gong
  • Publication number: 20180318261
    Abstract: The present invention relates to the use of a composition for preparing a medicament for the treatment of amyotrophic lateral sclerosis and associated disorders. The composition comprises 3-methyl-1-phenyl-2-pyrazoline-5-one or pharmaceutically acceptable salts thereof and borneol. The medicament is a drug used for delaying the occurrence time of amyotrophic lateral sclerosis and extending the survival time, and for improving memory function defect of amyotrophic lateral sclerosis.
    Type: Application
    Filed: June 8, 2016
    Publication date: November 8, 2018
    Inventors: Shibao Yang, Yao Hua, Zhengping Zhang, Rong Chen, Zhaolong Gong
  • Patent number: 9624315
    Abstract: The present invention relates to a process of a chemically synthetic drug, and in particular, to a new intermediate of a heparin pentasaccharide and a preparation method thereof. The process has high reaction efficiency, and an easy reaction operation. The reaction intermediate is easy to be purified, and is appropriate for an industrialization production.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: April 18, 2017
    Assignee: Zhejiang Hisum Pharmaceutical Co., Ltd.
    Inventors: Yanghui Guo, Hegeng Wei, Hua Bai, Yingqiu Wu, Yue Zhang, Junhui Zhou, Yili Ding, Lingwei Bai, Shibao Yang
  • Patent number: 9284330
    Abstract: Disclosed are 1,4-dihydro-naphthyridine derivatives and pharmaceutical composition and uses thereof. The 1,4-dihydro-naphthyridine derivatives are a compound capable of inhibiting acetylcholinesterase activity and preventing extracellular calcium from flowing into a cell via a calcium channel, i.e., having a dual-activity, which are of potential importance as a pharmaceutical and can be used to prepare the drugs for treating cardiovascular diseases, cerebrovascular diseases and dementia.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: March 15, 2016
    Assignee: Jiangsu Simovay Pharmaceutical Co., Ltd.
    Inventors: Rong Chen, Lin Feng, Zhengping Zhang, Fang Fang, Qingli Dong, Fulong Li, Lei Wang, Yao Hua, Shibao Yang, Peng Wang
  • Publication number: 20150299340
    Abstract: The present invention relates to a process of a chemically synthetic drug, and in particular, to a new intermediate of a heparin pentasaccharide and a preparation method thereof. The process has high reaction efficiency, and an easy reaction operation. The reaction intermediate is easy to be purified, and is appropriate for an industrialization production.
    Type: Application
    Filed: April 2, 2013
    Publication date: October 22, 2015
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Yanghui Guo, Hegeng Wei, Hua Bai, Yingqiu Wu, Yue Zhang, Junhui Zhou, Yili Ding, Lingwei Bai, Shibao Yang
  • Publication number: 20140364443
    Abstract: Disclosed are 1,4-dihydro-naphthyridine derivatives and pharmaceutical composition and uses thereof. The 1,4-dihydro-naphthyridine derivatives are a compound capable of inhibiting acetylcholinesterase activity and preventing extracellular calcium from flowing into a cell via a calcium channel, i.e., having a dual-activity, which are of potential importance as a pharmaceutical and can be used to prepare the drugs for treating cardiovascular diseases, cerebrovascular diseases and dementia.
    Type: Application
    Filed: December 7, 2012
    Publication date: December 11, 2014
    Applicant: Jiangsu Simovay Pharmaceutical Co., Ltd.
    Inventors: Rong Chen, Lin Feng, Zhengping Zhang, Fang Fang, Qingli Dong, Fulong Li, Lei Wang, Yao Hua, Shibao Yang, Peng Wang
  • Patent number: 8658684
    Abstract: A pharmaceutical composition comprises 3-methyl-1-phenyl-2-pyrazolin-5-one and borneol, and can be used to prepare the medicine for treating cerebrovascular diseases.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: February 25, 2014
    Assignee: Jiangsu Simcere Pharmaceutical R & D Co., Ltd.
    Inventors: Xiaojin Yin, Shibao Yang, Xiaoqiang Li, Zheng Jiang, Jian He, Anyuan Zhang, Xin Huang
  • Publication number: 20110003873
    Abstract: A pharmaceutical composition comprises 3-methyl-1-phenyl-2-pyrazolin-5-one and borneol, and can be used to prepare the medicine for treating cerebrovascular diseases.
    Type: Application
    Filed: March 3, 2009
    Publication date: January 6, 2011
    Applicant: Jiangsu Simcere Pharmaceutical R&D Co., Ltd.
    Inventors: Xiaojin Yin, Shibao Yang, Xiaoqiang Li, Zheng Jiang, Jian He, Anyuan Zhang, Xin Huang