Patents by Inventor Shigehisa Kawata

Shigehisa Kawata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230092306
    Abstract: According to one embodiment, a substance delivery carrier and a composition are used for delivering an intended substance to a myeloid tumor cell. The substance delivery carrier has a lipid particle, and an intended substance encapsulated in the lipid particle. The lipid particle contains, as a constituent thereof, at least a first lipid represented by formula (I).
    Type: Application
    Filed: April 1, 2022
    Publication date: March 23, 2023
    Applicants: KABUSHIKI KAISHA TOSHIBA, The University of Tokyo
    Inventors: Mitsuko ISHIHARA, Shigehisa KAWATA, Susumu GOYAMA
  • Publication number: 20230092732
    Abstract: According to one embodiment, a set of nucleic acid constructs which detects a DNA homologous recombination deficiency includes a first nucleic acid construct and a second nucleic acid construct. The first nucleic acid construct includes a first promoter sequence and a cleaved Cre gene ligated to downstream of the first promoter sequence. The second nucleic acid construct includes a second promoter sequence, a first loxP sequence ligated to downstream of the second promoter sequence, a reporter gene ligated to downstream of the first loxP sequence, and a second loxP sequence ligated to downstream of the reporter gene.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 23, 2023
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Shigehisa KAWATA, Mitsuko ISHIHARA
  • Publication number: 20220220568
    Abstract: According to one embodiment, a nucleic acid construct is used for detecting an estrogen-sensitive cell. The nucleic acid construct includes an enhancer sequence, a promoter sequence and a reporter gene. The enhancer sequence includes at least an ERE sequence and at least a XRE sequence. The promoter sequence is ligated to downstream of the enhancer sequence. The reporter gene is ligated to downstream of the promoter sequence.
    Type: Application
    Filed: December 16, 2021
    Publication date: July 14, 2022
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Shigehisa KAWATA, Mitsuko ISHIHARA
  • Publication number: 20210404021
    Abstract: According to one embodiment, a method for determining a characteristic of a tumor cell group, the method includes bringing a lipid particle including a lipid membrane and a first nucleic acid included in the lipid membrane into contact with the tumor cell group (the first nucleic acid including a promoter sequence of a marker gene for determining the characteristic and a reporter gene linked to a downstream of the promoter sequence to be functionable), culturing the tumor cell group, detecting the presence or absence or an amount of a signal from a reporter protein that is expressed from the reporter gene, in each tumor cell included in the tumor cell group, and counting the number of tumor cells having the characteristic that is measured from a result of the detecting.
    Type: Application
    Filed: September 9, 2021
    Publication date: December 30, 2021
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Shigehisa KAWATA, Mitsuko ISHIHARA, Saeko SARUWATARI
  • Publication number: 20210332129
    Abstract: A chicken B cell that expresses a variety of human antibodies.
    Type: Application
    Filed: May 7, 2021
    Publication date: October 28, 2021
    Inventors: Shuichi Hashimoto, Tomoaki Uchiki, Shigehisa Kawata, Kenjiro Asagoshi, Takashi Yabuki, Hitomi Sano, Shunsuke Miyai, Naoki Takahashi, Aki Takesue, Atsushi Sawada
  • Publication number: 20210102159
    Abstract: According to one embodiment, an examination device includes a reagent, a sheet and a detection unit. The reagent reacts with a measurement target and thereby causes light emission. The sheet is capable of adsorbing the reagent and gradually releasing the adsorbed reagent. The detection unit detects optical characteristics of the light emission caused by the reaction between the measurement target and the reagent.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Saeko SARUWATARI, Yoko TOKUNO, Ikuo UEMATSU, Mitsuko ISHIHARA, Shigehisa KAWATA, Eiichi AKAHOSHI, Takaaki WADA
  • Patent number: 8247643
    Abstract: A genetically modified animal that includes an introduced DNA including a functionally linked aryl hydrocarbon receptor-binding enhancer located 5?-upstream of a tyrosine hydroxylase gene, promoter of any type, reporter gene, and poly(A) addition signal.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: August 21, 2012
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Eiichi Akahoshi, Mitsuko Ishihara, Tomoyuki Shishido, Shigehisa Kawata
  • Publication number: 20100132057
    Abstract: A genetically modified animal that includes an introduced DNA including a functionally linked aryl hydrocarbon receptor-binding enhancer located 5?-upstream of a tyrosine hydroxylase gene, promoter of any type, reporter gene, and poly(A) addition signal.
    Type: Application
    Filed: September 14, 2009
    Publication date: May 27, 2010
    Inventors: Eiichi AKAHOSHI, Mitsuko Ishihara, Tomoyuki Shishido, Shigehisa Kawata