Patents by Inventor Shigekazu Matsukura

Shigekazu Matsukura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5808032
    Abstract: The L and H chains of the human anti-HBs antibody can be produced by the genetic recombination techniques to provide the desired human anti-HBs antibody easily on a large scale. The invention relates to nucleotide base sequences coding for the respective polypeptides that constitute the L and H chains of the anti-HBs antibody, expression plasmids containing them, and transformants prepared by transformation with the expression plasmids.
    Type: Grant
    Filed: April 5, 1994
    Date of Patent: September 15, 1998
    Assignee: Suntory Limited
    Inventors: Tatsuya Kurihara, Shigekazu Matsukura, Nobuo Tsuruoka, Kenji Arima, Tatsuro Nishihara
  • Patent number: 5059530
    Abstract: The present invention provides a vector plasmid capable of efficient tumor necrosis factor (TNF) production, a process capable of efficient TNF production in a host transformed with said plasmid and a composition containing the TNF produced by said process.The novel plasmid of the present invention is characterized by having inserted therein a DNA fragment that has a phage-derived promoter region upstream of a structural gene for TNF and in which a DNA fragment containing an E. coli gene-derived transcription termination coding base sequence (terminator) is joined immediately downstream of a base sequence coding for the termination of translation of said structural gene.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: October 22, 1991
    Assignee: Suntory Ltd.
    Inventors: Takehiro Oshima, Shoji Tanaka, Shigekazu Matsukura
  • Patent number: 4871663
    Abstract: The present invention provides a vector plasmid capable of efficient tumor necrosis factor (TNF) production, a process capable of efficient TNF production in a host transformed with said plasmid and a composition containing the TNF produced by said process.The novel plasmid of the present invention is characterized by having inserted therein a DNA fragment that has a phage-derived promoter region upstream of a structural gene for TNF and in which a DNA fragment containing an E. coli gene-derived transcription termination coding base sequence (terminator) is joined immediately downstream of a base sequence coding for the termination of translation of said structural gene.
    Type: Grant
    Filed: September 16, 1986
    Date of Patent: October 3, 1989
    Assignee: Suntory Limited
    Inventors: Takehiro Oshima, Shoji Tanaka, Shigekazu Matsukura