Shinichi Kojima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
Abstract: A cartridge adapter includes: a cartridge holder having a space that can accommodate therein a drug cartridge, the drug cartridge including a cylinder having a tubular internal space extending in a longitudinal direction, a gasket supported in the internal space so as to be movable in the longitudinal direction, and a drug held in the internal space; a piston that moves the gasket in the longitudinal direction in the internal space of the cylinder; a piston guide that movably supports the piston and connected to the cartridge holder; and a piston driving mechanism that drives the piston in the longitudinal direction.
Abstract: X-ray photons are counted as to each of energy bands (bins) to which optimum energy ranges are provided, and an image with reduced noise is displayed in a short time. An energy range of at least one of multiple energy bands in an X-ray detector is adjusted, on the basis of a distribution of degrees of X-ray attenuation at respective energy levels, the distribution of degrees of X-ray attenuation being measured in advance with respect to a predetermined direction of a subject. By using the X-ray detector with the energy bands after the adjustment, photon-counting CT imaging is performed.
Abstract: A corneal-reflection-based gaze detection section calculates a time series of a three-dimensional gaze vector in a camera coordinate system from a time series of facial images. A face position-and-orientation estimation section estimates a time series of a three-dimensional position and orientation of a face. An eyeball-center-coordinates transformation section calculates a time series of a three-dimensional position of the eyeball center in a coordinate system of a three-dimensional facial model. A fixed parameter calculation section calculates for use as a fixed parameter a three-dimensional position of the eyeball center in the three-dimensional facial-model coordinate system.
Abstract: An intake passage structure for an engine includes an intake port in a cylinder head of the engine, and connected to a combustion chamber to define an intake passage. The intake passage structure further includes a heat insulating member disposed along an inner surface of the intake port, and including a bulge having an upstream end surface which is a portion of an upstream end surface of the heat insulating member, the bulge has a radially outwardly protruding radially outer surface and has an increased wall thickness. The wall thickness of the bulge increases from downstream to upstream of the intake port. The upstream end surface of the bulge includes an injection machine connecting portion facing an injection gate configured to inject resin for forming the heat insulating member into the intake port.
Abstract: A bearing structure S includes: a bearing hole formed in a housing; a main body portion of a bearing provided in the bearing hole and inserted with a shaft therethrough; damper surface and provided on an outer circumferential surface of the main body portion, the damper surface facing an inner circumferential surface of the bearing hole; thrust surface provided at end portions of the main body portion in an axial direction of the shaft; and thrust back surface portions provided in the main body portion and having an outer diameter larger than those of the damper surface, the thrust back surface portions spaced apart from the damper surface by a distance farther than a distance between each of the damper surface and the inner circumferential surface of the bearing hole and positioned on back sides of the thrust surface.
Abstract: The present invention relates to N-((3S,4R)-1-((8-chloroquinoxalin-6-yl)carbonyl)-3-(4-fluorophenyl)piperidin-4-yl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide, which is a compound that can be useful for the treatment or prevention of SPT-related diseases including congenital diseases associated with the storage of sphingolipids, such as cancer and Niemann-Pick disease, or a salt thereof.
Abstract: An applicator (1) includes a main body (10), a parallel crank (40), and a lever (50). The parallel crank (40) includes a first crank bar (41) and a second crank bar (42). The first crank bar (41) and the second crank bar (42) each have one end portion swingably coupled to the main body (10). To the lever (50), another end portion of the first crank bar (41) and another end portion of the second crank bar (42) are each swingably coupled. The second crank bar (42) covers at least a part of side surfaces on both sides of the first crank bar (41) in an axial direction of a pin (43) as a rotation axis of the first crank bar (41) with respect to the main body (10) in a sandwiching manner.
Abstract: A bearing structure includes: a housing; a bearing hole, which is formed in the housing, and receives a bearing configured to axially support a shaft having one end provided with an impeller; a clearance groove, which is formed in an inner circumferential surface of the bearing hole, and communicates with a passage formed on a lower side of the shaft; and an inclined portion formed on an inner wall surface of the clearance groove, which is positioned at least above the shaft.
Abstract: An optical device unit that can operate very quietly and an image display apparatus having the optical device unit are provided. An optical device unit includes an optical device and a coupler joined to the optical device. The optical device includes an optical portion that is shaped as a plate and has a light incident surface on which light is incident, a movable portion that supports the optical portion, pivot portions that support the movable portion, and a support portion that supports the pivot portions. The support portion includes connection portions to which the pivot portions are connected and the connection portions are located away from the coupler.
Abstract: The present invention is directed to make a photon-counting CT apparatus capable of more accurate data acquisition. Such apparatus is provided with a reference detection unit and a time measuring instrument to measure temporal fluctuations in a rotational direction of an X-ray irradiation unit. The apparatus corrects temporal fluctuations in the rotational direction involved in data measured by the reference detection unit, using time measurement data which is output by the time measuring instrument. Using corrected measurement data measured by the reference detection unit, the apparatus makes corrections of fluctuations pertaining to the X-ray tube of the X-ray irradiation unit and pile-up. Data corrections with high accuracy are thus enabled.
Abstract: A locking member that locks a mixing nozzle to a cartridge that includes two syringes, the mixing nozzle being configured to mix the materials from the two syringes within the nozzle as the materials are discharged. The locking member includes a support rod supported on the mixing nozzle that is displaceable in a direction orthogonal to the direction in which the nozzle extends, and first and second engaging parts that engage with horizontal parts provided on the cartridge. The locking member further includes an inclined part that is inclined toward the opposite side to the nozzle, and that is provided between at least one of the first engaging part and the second engaging part, or between the second engaging part and the other end of the support rod.
Abstract: To provide an X-ray CT apparatus capable of correcting a difference of scattered radiation quantities contained in the projection data even in a case where a plurality of detection elements are disposed between collimator plates. The X-ray CT apparatus includes: an X-ray irradiation section for X-ray radiation; an X-ray detector including a plurality of detection elements for detecting the X-ray; a plurality of collimator plates disposed between the X-ray irradiation section and the X-ray detector so as to reduce scattered radiation; a reconstruction portion for reconstructing a tomographic image by using projection data generated based on an output from the X-ray detector; and a correction portion for correcting the projection data by using different correction functions according to the positions of the plural detection elements disposed between the collimator plates.
Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
Abstract: An information acquisition system includes an inner wall, an outer wall, and an antenna. The inner wall includes a reflective layer which reflects a radio wave. A reading space is located on an inner side of the reflective layer. Reading of tag information from an RF tag attached to an item is performed in the reading space. The outer wall is disposed on an opposite side of the inner wall from the reading space. The antenna is configured to output the radio wave toward the reading space in order to communicate with the RF tag. Between the inner wall and the outer wall, a peripheral space is provided. The reflective layer of the inner wall has a hole. The hole penetrates through the reflective layer in a thickness direction of the reflective layer.
Abstract: A bearing structure includes: a housing; a bearing hole formed in the housing and provided with a bearing for pivotally supporting a shaft; a clearance groove provided in the bearing hole, having an opposing wall portion radially opposed to the shaft, and communicating with an oil drainage passage provided below a shaft center of the shaft; and at least one of a narrow portion or a wide portion in the opposing wall portion of the clearance groove with a boundary right above the shaft center of the shaft, the narrow portion provided in a rear side in a rotation direction of the shaft, the narrow portion having a narrower gap from the shaft than that in a front side in the rotation direction of the shaft, the wide portion provided in the front side in the rotation direction of the shaft, the wide portion having a wider gap from the shaft than that in the rear side in the rotation direction of the shaft.
Abstract: A bearing structure includes a through-hole penetrating through in the axial direction of shaft, a bearing holder accommodated in the through-hole, a semi-floating metal bearing accommodated in the bearing holder and supporting the shaft inserted into the inside, and a positioning member being inserted into a radial direction of the shaft for both the bearing holder and the semi-floating metal bearing and regulating movement of the semi-floating metal bearing in the axial direction and in a rotating direction of the shaft relative to the bearing holder. For the bearing holder, a press-fit portion to be press-fitted into the through-hole is formed. A gap is formed between at least one of outer circumferential surfaces of both end parts of the bearing holder in the axial direction and the inner circumferential surface of the through-hole.
Abstract: A sight line direction estimation device includes: an imaging unit that captures an image of a head portion including an eyeball of a person; an apparent sight line direction derivation unit that derives an apparent sight line direction connecting a center position of the eyeball and an apparent pupil center position on a surface of the eyeball corresponding to a pupil center position based on the image captured by the imaging unit; and a sight line direction estimation unit that estimates an actual sight line direction of the person based on a predetermined corresponding relationship between an actual sight line direction and the apparent sight line direction and the apparent sight line direction derived by the sight line direction derivation unit.
Abstract: A shopping assistance system includes a moving device (bagging device) and an information acquisition device. The moving device includes a support portion and a guide portion. The support portion is provided with a placement surface on which a product with an RF tag is placed. The guide portion includes a shielding space for shielding radio waves therein, and is disposed around the support portion along outer circumferential edges of the placement surface. The information acquisition device reads product information from the RF tag by performing wireless communication with the RF tag using an antenna when a relative positional relationship between a communication area of the antenna and the RF tag changes in the shielding space, the communication area being an area which is set around the antenna and in which wireless communication with the RF tag is performed.