Abstract: Provided are a walking ability improver for improving walking ability, and a health-related QOL improver for improving mental health. The walking ability improver contains a component derived from a lactic acid bacterium belonging to the genus Lactobacillus. The health-related QOL improver contains a component derived from a lactic acid bacterium belonging to the genus Lactobacillus, and improves mental health.

Abstract: A magnetic tape having excellent high recording density characteristics, good durability and good servo-tracking characteristics, which comprises a non-magnetic support, a magnetic layer formed on one surface of the non-magnetic support and containing a magnetic powder, a primer layer provided between the non-magnetic support and the magnetic layer and containing a non-magnetic powder, and a back coat layer formed on the other surface of the non-magnetic support, wherein the non-magnetic powder is goethite particles having an average particle size in a range of from 5 nm to 100 nm and the magnetic tape has an edge weave amount of 1.0 ?m or less.

Abstract: A width of a circuit device isolation region and a width of a device region formed on a semiconductor substrate are determined in such a manner as to satisfy a condition which prevents the occurrence of dislocation due to thermal oxidation for forming the isolation region. A semiconductor device can be fabrication which includes a semiconductor substrate, a plurality of circuit regions formed on a device formation region in the semiconductor substrate and having a width of 0.1 to 125 &mgr;m and device isolation regions so formed on the semiconductor substrate as to isolate a plurality of circuit regions from one another and having a width of 0.05 to 2.5 &mgr;m, and wherein a ratio of the width of the device isolation region to the width of a plurality of circuit regions adjacent to the device isolation region is from 2 to 50.

Abstract: A semiconductor device includes a thermal oxide film for isolation, a semiconductor region that becomes an element forming region with the circumference thereof surrounded by the oxide film and diffused resistance layers in the semiconductor region and provides a structure for controlling resistance value variation of diffused resistors originated in a stress generated at time of forming the oxide film for isolation. A distance between an end portion on a longer side closest to a thermal oxide film of the diffused layer and an end of the thermal oxide film is apart from each other by a predetermined value determined by stress distribution in the semiconductor region or by at least 4 .mu.

Abstract: The present invention provides a novel purine 4'-thioarabinonucleoside represented by the following formula ?1!: ##STR1## wherein B represents a purine base other than adenine. Also disclosed are a method for preparing the purine 4'-thioarabinonucleoside and pharmaceutical compositions containing the purine 4'-thioarabinonucleoside.

Abstract: Novel 2'-methylidenenucleotide compounds of the formula (I) ##STR1## wherein R is a hydrogen or a halogen, R.sup.1 and R.sup.2 are the same or different and each is a fatty acid residue or a hydrocarbon residue, and R.sup.3 and R.sup.4 are the same or different and each is a hydrogen, a halogen or an alkyl; salts thereof; methods for production thereof; and pharmaceutical use thereof. The compounds and salts thereof show an excellent antitumor effect in mammals. More specifically, they show a remarkable activity of inhibiting growth of mouse tumors, cultured human tumor cells, and human tumors transplanted to nude mice, and are useful for the treatment and prevention of recurrence of lung cancer, gastrointestinal cancer, breast cancer, cervical cancer, gynecological cancer, urinological cancer, leukemia, melanoma, lymphogenous metastatic tumor and the like in mammals. They are also useful as antitumor agents since they have an increased bioavailability and low toxicity.

Abstract: A nondestructive inspecting apparatus is arranged to have an exciting magnet for applying an ac magnetic field to a sample and a SQUID for converting change of a magnetic characteristic of the sample occurring when the ac magnetic field is applied to the sample into an electric signal. The exciting magnet is a cancelled coil assembly composed of plural coils having respective polarities.

Abstract: The present invention relates to a novel compound represented by the following formula [I] which is useful as a synthetic intermediate of a 2-alkynyladenosine.The present invention also relates to a process for producing the compound and a process for producing a 2-alkynyladenosine [IV] by way of the compound.Further, the present invention relates to a 2-alkynyladenosine derivative represented by the following formula [V] having excellent storage stability and, to a method of storing the 2-alkynyladenosine in the form of that derivative. ##STR1## [I] A=a leaving group, [II] A=NH.sub.2,[V] A=NHR.sup.4,wherein R.sup.1 through R.sup.4 represent a hydrogen atom or a protective group, and n denotes an integer of 1 to 15, provided that R.sup.1 through R.sup.4 do not represent a hydrogen atom simultaneously.

Abstract: The present invention relates to a novel 1-.beta.-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivative represented by the following formula (I), whose concentration in blood as XVAU can be kept high for many hours when it is administered orally.The present invention also relates to an antiviral agent comprising as an active ingredient the compound of the present invention.Further, the present invention relates to a method for treating viral diseases which comprises administering to a patient with a viral disease a safe and effective amount of the compound of the present invention. ##STR1## wherein X represents a halogen; and R.sup.1, R.sup.2, and R.sup.3, which may be the same or different, each represent a hydrogen atom, a lower alkyl group or an aralkyl group, provided that R.sup.1, R.sup.2 and R.sup.3 are not hydrogen at the same time.

Abstract: Novel stable, non-hygroscopic 2'-deoxy-2'-methylidenecytidine dihydrate and its methods for production, and compositions with improved solubility containing same and saccharide(s).

Abstract: The present invention relates to an anxiolytic drug comprising as an active ingredient a 1-amino-5-halogenouracil represented by formula [I]: ##STR1## wherein X represents a halogen atom, or pharmaceutically acceptable salt thereof.

Abstract: A method of maintaining the housing of a reactor pressure vessel having: a reactor pressure vessel into which cooling water is introduced; a cylindrical housing which penetrates an end bracket of the reactor pressure vessel; and a circumferential weld for securing the intermediate portion of the housing to the reactor pressure vessel by welding, the method of maintaining a housing of a reactor pressure vessel comprising the steps of: remaining the cooling water in the reactor pressure vessel; preventing leakage of the cooling water in the reactor pressure vessel through the housing by sealing the housing; making the inside portion of the housing lower than the seal to be a hollow space of a gas atmosphere; heating a heat affected zone due to welding by using a heating device inserted into the hollow space from a lower portion so as to compressive-yield the inner surface of the housing in the heat affected portion upper than the circumferential weld and tensile-yield the outer surface; and cooling heated porti

Abstract: The present invention is directed to a cap assembly for screwing into an opening of a reservoir for storing a fluid therein. Around the cap, formed is a sealing groove in which a sealing member is disposed. The sealing member has a sealing portion which extends toward the inner periphery of the opening, and a pair of contacting portions which extend axially toward each inner side of the sealing groove in spaced relationship with each inner side of the sealing groove by a predetermined clearance respectively. The sealing member is formed around the periphery thereof with grooves for allowing the sealing portion and contacting portions to be deflected in response to a sliding motion of the sealing member when the cap assembly is screwed into the opening.

Abstract: A reservoir tank includes a tank body storing an amount of operating fluid and having an inlet, a cap detachably mounted on the inlet of the tank body, a deflector secured to the cap so as to be located in the inlet and having a first passage which is in fluid communication with the atmosphere and a second passage which is in fluid communication with an inner space of the tank body, a diaphragm located between the cap and the deflector and having a slit valve which is set to be opened by a pressure difference thereacross, and an interruption body located between the deflector and the diaphragm so as to oppose to the second passage of the deflector and having a passage which enabling the fluid communication between the second passage of the deflector and the slit.

Abstract: A reservoir tank according to the present invention is comprised of a tank body storing an amount of operating fluid, connected to a specific device for supplying thereinto the operating fluid and having a bottom with a hole isolated from the operating fluid; a float movable in the vertical direction according to the variation of the liquid level of the operating fluid; a magnet secured to a lower end of the float; and a reed switch unit assembly having a reed switch with a pair of terminals, a pair of conducting elements connected to the pair of terminals of the reed switch, a connector casing, and a pair of connectors each of which is secured to one end of the connector casing in such a manner that each connector is electrically connected to the respective conducting element.

Abstract: Disclosed are a central nervous system depressant which comprises a 1-amino-5-halogenouracil represented by the formula ##STR1## wherein X represents a halogen atom, or a pharmaceutically acceptable salt thereof as an active ingredient;a 1-amino-5-halogenouracil represented by the formula ##STR2## wherein X' represents chlorine, bromine or iodine, or a salt thereof; and a process for preparing a 1-amino-5-halogenouracil represented by the above shown formula [I] from a pyrimidine derivative represented by the formula ##STR3## wherein X represents a halogen atom and R represents a protective group.

Abstract: Novel stable, non-hygroscopic 2'-deoxy-2'-methylidenecytidine dihydrate and its methods for production, and compositions with improved solubility containing same and saccharide(s).

Abstract: A method and apparatus for inspecting the change in a water quality in terms of the change in a corrosion rate by detecting the capacity change between opposed electrodes due to the corrosion of electrode surfaces. As a result, the water quality can be continuously monitored over a long time while leaving the electrodes in the water to be inspected. Thus, the method and apparatus are suited for controlling the water quality especially in an atomic reactor vessel.

Abstract: Pyrimidine 2'-deoxy-2'-methylidene nucleoside compounds: ##STR1## wherein R.sup.1 represents amino, hydroxy, silylamino, silyloxy, acylamino or acyloxy; R.sup.2 represents hydrogen, halogen, a lower alkyl, a lower alkenyl, a lower alkynyl or haloalkyl; R.sup.3 and R.sup.4 represent the same or different hydrogen, silyl, acyl or aminoacyl, or a pharmaceutically acceptable salt or hydrate thereof, except that R.sup.1 is amino or hydroxy, and both of R.sup.3 and R.sup.4 are hydrogen.Said compounds possess excellent antitumor and antiviral activities, thus providing novel anticancer and antiviral agent.

Abstract: A master cylinder includes a valve that is slidably mounted in a movable piston means for limited axial movement therein between a closed position wherein the valve is sealingly engaged with the piston and an open position wherein a gap is maintained between the valve and the piston. The valve includes a passage for providing fluid communication between the supply chamber and the pressure chamber when the valve is in the open position. An orifice in the piston limits the flow of fluid from the pressure chamber to the supply chamber at least during the limited movement of the valve from the open position to closed position. An overflow arrangement on the piston is responsive to movement of the piston against the bias of a biasing device for establishing fluid communication between the passage and the supply chamber only when the valve is in the closed position.